BROOKLYN COMMUNITY CLINICAL ONCOLOGY PROGRAM

布鲁克林社区临床肿瘤学计划

• 批准号: 3559014
• 负责人: SAMEER S RAFLA
• 金额: $ 12.29万
• 依托单位: NEW YORK METHODIST HOSPITAL
• 依托单位国家: 美国
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-09-30 至 1994-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3559014
• 关键词: 13 cis retinoate; Hodgkin's disease; acute leukemia; adenocarcinoma; androgen inhibitor; antineoplastics; autologous transplantation; bladder neoplasm; bleomycin; bone marrow transplantation; breast neoplasm /cancer diagnosis; breast neoplasms; breast surgery; cancer information system; cancer prevention; cancer registry /resource; cancer rehabilitation /care; cancer risk; carcinogenesis inhibitor; central nervous system neoplasms; chlorambucil; cis platinum compound; clinical trials; colorectal neoplasms; combination chemotherapy; community health services; cooperative study; cyclophosphamide; cytosine arabinoside; dacarbazine; deoxycoformycin; doxorubicin; esophagus neoplasm; etoposide; fluorouracil; head /neck neoplasm; health science research analysis /evaluation; homologous transplantation; human subject; human therapy evaluation; leucovorin; levamisole; lomustine; lymphoma; mechlorethamine; methotrexate; neoplasm /cancer chemotherapy; neoplasm /cancer education; neoplasm /cancer nutrition therapy; neoplasm /cancer radionuclide therapy; neoplasm /cancer surgery; neoplasm /cancer therapy; prednisone; procarbazine; prostate neoplasms; radiosensitizer; sarcoma; small cell lung cancer; smoking cessation; tamoxifen; therapy compliance; vincristine

This application from the Cancer Institute of Brooklyn (CIB) is submitted in response to RFA 90-CA-13. The applicant organization, the CIB, is a free-standing entity supported by two of the consortium institutions, and affiliated with the other two. The CIB will serve as the "umbrella" and central focus of this research effort. All four hospitals are located in the southern half of the borough of Brooklyn with a catchment area of more than 1 million people. Fifty board-certified physicians have committeed their support to this project, which anticipates contributing 120 patients to clinical treatment trials and 92 to cancer control studies. This will be accomplished through agreements with three research bases: NSABP, ECOG, and RTOG. The specific aims developed for the Brooklyn CCOP are: 1) Coordination and expansion of existing research resources; 2) development and support of the investigators' research; 3) provision of comprehensive data management support; 4) collaboration with the research bases to optimize accrual; 5) expansion of the data management system; 6) development of a patient identification process; 7) implementation of a quality control program; 8) execution of a protocol selection process; 9) enforcement of investigator standards; 10) expansion of existing cancer control protocol activities; 11) increasing the involvement and awareness of primary care physicians; 12) expansion of this research effort to include other physicians and/or institutions in the catchment area; and 15) dissemination of research information to the Brooklyn medical community. Experienced physician leadership and support staff in addition to well- equipped facilities will enhance the development and implementation of this community research effort.

这份来自布鲁克林癌症研究所 (CIB) 的申请是 响应 RFA 90-CA-13 提交。 申请组织、 CIB，是一个独立的实体，由两个财团支持 机构，并隶属于另外两个机构。 CIB 将作为 这项研究工作的“保护伞”和中心焦点。 所有四个 医院位于布鲁克林区的南半部 服务人口超过100万。 五十 委员会认证的医生已承诺对此表示支持 项目预计将有 120 名患者参与临床 治疗试验和 92 项癌症控制研究。 这将是 通过与三个研究基地达成协议来完成：NSABP、ECOG、 和 RTOG。 布鲁克林 CCOP 制定的具体目标是： 1) 协调 以及扩大现有的研究资源； 2）开发与支持 研究人员的研究； 3）提供全面的数据 管理支持； 4）与研究基地的协作优化 应计费用； 5）数据管理系统的扩展； 6) 开发一个 患者身份识别过程； 7) 实施质量控制 程序; 8) 执行协议选择过程； 9) 执行 研究者标准； 10) 扩大现有的癌症控制 礼宾活动； 11) 提高参与度和意识 初级保健医生； 12）将这项研究工作扩展到 包括服务范围内的其他医生和/或机构；和 15) 向布鲁克林医学中心传播研究信息 社区。 经验丰富的医生领导和支持人员以及良好的 配备齐全的设施将促进开发和实施 这项社区研究工作。