CORE--BIOMETRY

核心--生物测定学

• 批准号: 6235862
• 负责人: EDWARD H GIANNINI
• 金额: $ 10.8万
• 依托单位: CINCINNATI CHILDRENS HOSP MED CTR
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-06-01 至 1998-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6235862
• 关键词: biomedical facility; human tissue; information systems; juvenile rheumatoid arthritis; statistical service /center; statistics /biometry; tissue resource /registry

A Biometry Core is proposed as a resource that will be available to investigators of all Center projects and to other investigators who contribute to the research base, both BIOMED and EEHSR, pursuing projects related to arthritis and musculoskeletal conditions. The principal functions of this core are; 1) to assist investigators ina the design, conduct, analysis, and reporting of their studies; 2) to maintain national registry and clinical databanks needed as special resources for investigators both internal and external to the Center; 3) train investigators, graduate students, and other staff in the proper methods of study design, conduct, analysis, and reporting of studies; 4) manage the tissue repository. Edward H. Giannini, MSc, DrPH, is the proposed Director of this core, and Shumei Guo, PhD, will serve as the senior biostatistician. The operation of the Exploratory Research Center for Juvenile Rheumatic Diseases, which began in September of 1993, as well as numerous external collaborations, has allowed Dr. Giannini to develop and mature the Biometry core during the last 2 years. The tissue repository, which presently contains 1377 tissues, is an important special resource located within this core. Robert A. Colbert, MD, PhD, is the proposed manager of the repository. During the operation of this project, the repository will log aliquot tissues including serum, DNA,a nd synovium from children with pediatric rheumatic disease. Investigators, both from within the Center and external to it, will have access to this important resource. Specifically, tissue repository personnel will: 1) collect and store samples from well characterized patients with pediatric rheumatic illness; 2) provide and maintain a log and monitor the use of these samples; 3) continuously replenish samples as required to maintain the viability of the repository.

提出了一个生物特征核心作为一种资源 所有中心项目的调查人员以及其他调查人员 为Biomed和EEHSR的研究基础做出贡献，从事项目 与关节炎和肌肉骨骼疾病有关。 校长 该核心的功能是； 1）协助研究人员INA设计，进行，分析和 报告他们的研究； 2）维护需要特殊的国家注册表和临床数据库 内部和外部调查人员的资源； 3）适当的培训调查员，研究生和其他员工 研究设计，进行，分析和报告的方法； 4）管理组织存储库。 Edward H. Giannini，MSC，DRPH是该核心的拟议主任， Shumei Guo博士将担任高级生物统计学家。 操作 少年风湿病探索性研究中心 始于1993年9月，以及许多外部合作， 允许Giannini博士开发并成熟生物特征核心核心 最近两年。 目前包含1377个组织的组织存储库是 重要的特殊资源位于此核心内。 罗伯特·A·科尔伯特（Robert A. Colbert）， MD博士是存储库的拟议经理。 在操作过程中 在这个项目中，存储库将记录包括血清在内的等分试样， DNA，以及儿童风湿病儿童的滑膜。 来自中心内部和外部的调查人员将有 访问此重要资源。 具体而言，组织存储库 人员将： 1）收集和存储来自特征良好的患者的样品 小儿风湿病； 2）提供并维护日志并监视这些样品的使用； 3）不断补充样品，以维持的生存能力 存储库。