MID CAREER INVESTIGATOR AWARD

职业中期研究员奖

• 批准号: 6038503
• 负责人: JOAN H SCHILLER
• 金额: $ 10.82万
• 依托单位: UNIVERSITY OF WISCONSIN-MADISON
• 依托单位国家: 美国
• 财政年份: 2000
• 资助国家: 美国
• 起止时间: 2000-09-11 至 2005-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6038503
• 关键词: angiogenesis inhibitors; carboplatin; cis platinum compound; clinical research; clinical trial phase I; combination cancer therapy; combination chemotherapy; cyclophosphamide; doxorubicin; etoposide; gemcitabine; guanine nucleotide binding protein; human subject; mesothelioma; neoplasm /cancer chemotherapy; neoplasm /cancer radiation therapy; nonsmall cell lung cancer; p53 gene /protein; paclitaxel; role model; small cell lung cancer; topotecan; vinblastine; vincristine

DESCRIPTION: (Applicant's Description) This application proposes Joan H. Schiller, M.D., for a K24 Mid-Career Investigator Award in Patient Oriented Research. Dr. Schiller is currently one of only two tenured women physicians in the University of Wisconsin Department of Medicine, and an accomplished medical oncologist with an active clinical and translational research program in lung cancer. Dr. Schiller is active in drug development in lung cancer, participating at all levels of clinical research, including Phase I, II, and III trials. In addition to running an active Phase II program at the UW and participating in the UWCCC Phase I program, she is co-chair of the Eastern Co- Operative Group (ECOG) Thoracic Committee, and chair of two ECOG multi- institutional Phase III studies. Dr. Schiller intends to use the release time from her heavy clinical and administrative responsibilities to expand her scope of clinical research in lung cancer, develop a mentoring program for young investigators, and to further develop her own mentoring and leadership skills. Her specific aims within this award are (1) to draw upon the considerable campus-wide resources in basic and translational research at the UW, so as to facilitate interdisciplinary collaborations and development of a UW clinical lung cancer research program that engages the participation of researchers from multiple disciplines; (2) to develop a mentoring program for residents and fellows for tobacco-related neoplasms and associated clinical research, (3) to support her activities in clinical research in lung cancer, and enhance her own development as an academic leader in the field of lung cancer, and (4) to foster the career development of women clinical scientists and leaders in academic medicine. In this application, Dr. Schiller demonstrates (a) her strong clinical research interest in lung cancer, and accomplishments in the field; (b) an outstanding basic science and clinical environment within the UW in which to conduct patient-oriented, translational research; (c) her unique position within the institution to nurture the careers of women junior investigators, and (d) the need for protected research time to continue these efforts.

描述：（申请人的描述）本申请提出 Joan H. Schiller 医学博士荣获 K24 以患者为导向的职业生涯中期研究员奖 研究。 席勒博士是目前仅有的两名终身女医生之一 在威斯康星大学医学系，并取得了成就 拥有活跃的临床和转化研究项目的肿瘤内科医生 在肺癌中。 Schiller 博士积极致力于肺癌药物开发， 参与各个级别的临床研究，包括 I 期、II 期和 三、试验。 除了在华盛顿大学运行一个活跃的第二阶段项目之外 参加UWCCC第一阶段项目，她是东部联合委员会的联合主席 手术组 (ECOG) 胸科委员会，以及两个 ECOG 多学科委员会主席 机构第三阶段研究。 席勒博士打算利用释放时间 从繁重的临床和行政职责中解脱出来，扩大她的 肺癌临床研究的范围，制定指导计划 年轻的研究人员，并进一步发展她自己的指导和领导能力 技能。 她在该奖项中的具体目标是（1）利用 在基础和转化研究方面拥有大量的全校资源 华盛顿大学，以促进跨学科合作和发展 华盛顿大学临床肺癌研究计划，涉及 来自多个学科的研究人员； (2)制定辅导计划 烟草相关肿瘤及相关临床的住院医师和研究员 研究，(3) 支持她在肺癌临床研究方面的活动， 并促进她作为肺领域学术带头人的自身发展 癌症，(4) 促进女性临床科学家的职业发展 和学术医学领域的领导者。 在此应用程序中，席勒博士 展示了 (a) 她对肺癌的强烈临床研究兴趣，以及 领域内的成就； (b) 杰出的基础科学和临床 华盛顿大学内的环境，在其中进行以患者为中心的转化 研究; (c) 她在机构内的独特地位，以培养 女性初级研究员的职业生涯，以及 (d) 受保护研究的需要 是时候继续这些努力了。