UT Southwestern NCI National Clinical Trials Network Lead Academic Site - U10

UT 西南 NCI 国家临床试验网络主要学术网站 - U10

• 批准号: 9206742
• 负责人: JOAN H SCHILLER
• 金额: $ 5万
• 依托单位: UT SOUTHWESTERN MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-04-09 至 2019-02-28
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9206742
• 关键词: Academic Medical Centers; Adult; African American; American Cancer Society; American College of Radiology Imaging Network; American College of Surgeons Oncology Group; American Society of Clinical Oncology; Area; Basic Science; Breast; Cancer Center; Chest; Clinic; Clinical; Clinical Research; Clinical Trials; Collaborations; Country; Department chair; Discipline; Disease; Eastern Cooperative Oncology Group; Enrollment; Ethics; Ethnic Origin; Faculty; Funding; Grant; Gynecologic Oncology Group; Head and neck structure; Health; Hematology; Heme; Hispanics; Image; Institution; Lead; Leadership; Lung; Magnetic Resonance Imaging; Malignant neoplasm of lung; Medical center; Mentors; NCI-Designated Cancer Center; National Clinical Trials Network; National Surgical Adjuvant Breast and Bowel Project; Oncology Group; Patients; Physician Executives; Population; Positioning Attribute; Positron-Emission Tomography; Principal Investigator; Publications; Radiation Oncology; Radiation Therapy Oncology Group; Recording of previous events; Recruitment Activity; Research; Research Personnel; Role; Services; Site; Southwest Oncology Group; Texas; Therapeutic Trials; Translating; Translational Research; Universities; abstracting; cancer diagnosis; career development; drug discovery; ethnic minority population; innovation; medical schools; member; metropolitan; multidisciplinary; neuro-oncology; oncology; patient population; programs; quantitative imaging; racial and ethnic; racial minority

DESCRIPTION (provided by applicant): The University of Texas Southwestern Medical Center (UTSW) has a history of leadership, translational research, and accrual to cooperative group trials. The PI of this grant is Dr. Joan Schiller, chief of the Division of Heme/Oncology and Deputy Director of the Simmons Cancer Center (SCC), former Chair of ECOG's Thoracic Committee and currently PI of UTSW's main institution ECOG grant. Co-investigators include Dr. Hak Choy, Chair of UTSW's Department of Radiation Oncology, Vice Chair for Disease Sites in RTOG, and former Chair of RTOG's Thoracic Committee; Dr. David Miller, member of the GOG Board of Directors and Chair of the Uterine Corpus Committee; Dr. Marilyn Leitch, member of the Executive Committee of ACOSOG, and Dr. Phil Evans, immediate past president of the American Cancer Society, who was one of the founding members of the ACRIN Breast committee, and served as the principal investigator at UTSW for ACRIN sponsored trials. In 2012, UTSW enrolled 105 patients on adult co-operative group trials. Since 2006, UTSW faculty have investigated or co-investigated 96 co-operative group publications and 85 abstracts, and have chaired, co-chaired, or served as cooperative committee chair on 34 cooperative group trials. UTSW is also a site for the NCI Centers Quantitative imaging Excellence. UTSW is the only academic medical center and medical school in the Dallas/Ft. Worth (DFW) Metroplex, the fourth largest metropolitan area in the country, and is the only NCI designated Cancer Center in north Texas. UTSW also has a strong clinical and transitional research program and drug discovery program; a SPORE in lung cancer; an Advanced Imaging Research Center; and has access to a diverse ethnic and racial population. In the DFW Metroplex, roughly 10.3% of the populations with a cancer diagnosis are Hispanic, and 14.1% are African American; in 2012, 29.6% of SCC patients going on co-operative group clinical studies were of Hispanic ethnicity, and 13.6% were of African American ancestry. The specific aims of the UTSW UIO are to contribute to and promote: (1) The NCTN by enrolling patients with diverse ethnic and racial background on therapeutic and non-therapeutic trials; (2) The scientific direction of the NCTN by bringing the basic, translational, and imaging research conducted at UTSW into hypothesis driven clinical trials. (3) Multidisciplinary efforts and collaboration across multiple disciplinesand multiple cooperative groups; (4) Service in leadership roles by chairing and co-chairing clinical trials and committees, and by participating in NCI activities and initiatives; and (5) The career development of junior faculty.

描述（由申请人提供）：德克萨斯大学西南医学中心（UTSW）具有领导力，转化研究的历史，并应对合作小组试验。该赠款的PI是血红素/肿瘤学系负责人Joan Schiller博士和 ECOG胸部委员会的前主席，目前是UTSW主要机构ECOG Grant的PI。共同研究人员包括UTSW辐射肿瘤学系主任，RTOG疾病现场副主席Hak Choy博士，以及RTOG胸部委员会的前主席； GOG董事会成员兼子宫语料库委员会主席David Miller博士； Acosog执行委员会委员Marilyn Leitch博士和美国癌症协会的前任主席Phil Evans博士是Acrin乳房委员会的创始成员之一，并在UTSW担任ACRIN赞助试验的UTSW的首席研究员。 2012年，UTSW招募了105名成人合作组试验患者。自2006年以来，UTSW教职员工已经调查或共同研究了96个合作小组出版物和85个摘要，并担任了34个合作小组审判的合作主席或担任合作委员会主席。 UTSW还是NCI中心卓越定量成像的网站。 UTSW是达拉斯/英尺唯一的学术医学中心和医学院。价值（DFW）Metroplex是该国第四大都市地区，也是北德克萨斯州唯一的NCI指定癌症中心。 UTSW还具有强大的临床和过渡研究计划和药物发现计划；肺癌的孢子；先进的成像研究中心；并可以使用多样化的种族和种族人口。在DFW Metroplex中，大约10.3％的癌症诊断人群是西班牙裔，14.1％是非裔美国人。 2012年，参加合作组临床研究的SCC患者中有29.6％是西班牙裔种族，而13.6％的患者为非裔美国人的血统。 UTSW UIO的具体目的是为：（1）NCTN通过在治疗和非治疗试验的种族和种族背景的患者中注册； （2）NCTN的科学方向通过将在UTSW进行的基本，转化和成像研究带入假设驱动的临床试验。 （3）跨多个学科和多个合作团体的多学科努力和合作； （4）主持和共同主持临床试验和委员会以及参与NCI活动和计划，担任领导职务； （5）初级教师的职业发展。