INEXPENSIVE MODULAR FLOW CYTOMETERS: A NEW GENERATION

廉价的模块化流式细胞仪：新一代

• 批准号: 6015024
• 负责人: HOWARD M. SHAPIRO
• 金额: $ 37.85万
• 依托单位: HOWARD M. SHAPIRO, MD, P.C.
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-03-15 至 2001-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6015024
• 关键词: bioengineering /biomedical engineering; biomedical equipment development; computer program /software; computer system design /evaluation; computer system hardware; flow cytometry

Although flow cytometers have become indispensable to researchers in many areas of biology and medicine who study the normal and abnormal behavior of cells, acquisition costs of apparatus remain high. Recent advances in laser, reagent and electronic technology now make it possible to build multiparameter flow cytometers using inexpensive diode and solid-state laser sources, with digital signal processing electronics, which can match, and in some cases, surpass the performance of existing instruments for a fraction of the price. This project will develop and test a low-cost flow cytometer, and evaluate optical and electronic approaches to improving performance of such instruments. PROPOSED COMMERCIAL APPLICATION The apparatus to be developed should make an important technology available to hundreds of laboratories not now able to afford it.

尽管流式细胞仪已成为许多生物学和医学领域研究细胞正常和异常行为的研究人员不可或缺的工具，但设备的购置成本仍然很高。 激光、试剂和电子技术的最新进展现在使得使用廉价的二极管和固态激光源以及数字信号处理电子设备构建多参数流式细胞仪成为可能，这些流式细胞仪可以匹配甚至在某些情况下超越现有仪器的性能价格的一小部分。 该项目将开发和测试低成本流式细胞仪，并评估光学和电子方法以提高此类仪器的性能。拟议的商业应用 待开发的设备应为数百个现在无力承担的实验室提供一项重要技术。