STUDY OF FUNCTIONAL OUTCOME AFTER TRAUMA IN ADOLESCENTS

青少年创伤后功能结果的研究

• 批准号: 6078088
• 负责人: TROY L HOLBROOK
• 金额: $ 22.42万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-09-30 至 2003-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6078088
• 关键词: adolescence (12-20); child mental disorders; clinical research; depression; functional ability; human subject; medical rehabilitation related tag; outcomes research; posttraumatic stress disorder; questionnaires; rehabilitation; social support network; socioeconomics; trauma

Little is known about the degree of disability, quality of life, and psychological well-being after major trauma in adolescents aged 12 to 17 years. This is a proposal to determine by prospective epidemiologic study the incidence and determinants of functional limitation after major trauma in adolescent children aged 12 to 17 years. Using the computerized San Diego County Regional Trauma System Registry (TREG) trauma patient data base (Appendix I), we propose to determine the incidence and predictors of functional limitation after major trauma in approximately 525 male and female adolescents aged 12 to 17 years admitted prospectively to six trauma centers in San Diego County. Functional limitation after major trauma will be measured using the Quality of Well-being (QWB) scale at six time points; at discharge, and 3, 6, 12, 18, and 24 months after discharge. Multiple possible predictors of functional limitation after major trauma that will be determined include: (1) injury severity and body area(s) injured, injury event-related factors including mechanism, (2) clinical course and treatment of the trauma, (3) sociodemographic characteristics, (4) social support and (5) post-injury psychological sequelae including depression and post-traumatic stress disorder. The proposed project is designed to provide an ideal opportunity to itegrate with the existing enrollment protocol of the TRP study, which successfully recruited adult research subjects from four of the six Trauma Center hospitals targeted for enrollment of adolescents. Significantly, this proposal will provide a large outcome database on approximately 525 male and female adolescents aged 12 to 17 years that will allow us to determine not only the incidence of functional limitation after major trauma but also the strength and independence of predictors of functional limitation. Understanding the factors which lead to functional limitation in adolescents will allow physicians and health care personnel to target high risk patients for appropriate intervention and therapy. It will also provide necessary data for the effective delivery of rehabilitative and support services to adolescent trauma victims. The true efficacy of trauma care systems in this country can only be demonstrated by addressing whether these systems return trauma victims to active functional roles in society.

关于残疾，生活质量和 在12岁至12岁的青少年重大创伤之后的心理健康 17年。 这是通过潜在流行病学来确定的建议 研究功能限制的发生率和决定因素 12至17岁的青少年儿童的重大创伤。 使用 计算机化的圣地亚哥县区域创伤系统登记处（TREG） 创伤患者数据库（附录I），我们建议确定 重大创伤后功能限制的发生率和预测指标 大约525名12至17岁的男性和女性青少年 前瞻性地进入了圣地亚哥县的六个创伤中心。 重大创伤后的功能限制将使用 幸福质量（QWB）在六个时间点上；出院时 出院后的3、6、12、18和24个月。多个可能 重大创伤后功能限制的预测指标 确定包括：（1）受伤严重性和身体区域受伤，伤害 事件相关的因素，包括机制，（2）临床过程和 创伤的治疗，（3）社会人口统计学特征，（4） 社会支持和（5）伤害后的心理后遗症，包括 抑郁和创伤后应激障碍。 拟议的项目旨在提供理想的机会 通过TRP研究的现有入学方案进行迭代，该方案 从六个中的四个中成功招募了成人研究对象 创伤中心医院的目标是入学。 值得注意的是，该建议将在 大约有525名12至17岁的男性和女性青少年 将使我们不仅确定功能的发生率 重大创伤之后的限制，但也有实力和独立性 功能限制的预测指标。 了解哪些因素 导致青少年的功能限制将允许医生和 医疗保健人员以适当的态度针对高风险患者 干预和治疗。 它还将为 有效地向青少年提供康复和支持服务 创伤受害者。 创伤护理系统的真正功效 只能通过解决这些系统是否可以证明国家 将创伤受害者归还在社会上的积极职能角色。