PROSPECTIVE STUDY OF FUNCTIONAL LIMITATION AFTER TRAUMA

创伤后功能限制的前瞻性研究

• 批准号: 2236142
• 负责人: TROY L HOLBROOK
• 金额: $ 42.06万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 1993
• 资助国家: 美国
• 起止时间: 1993-08-01 至 1998-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2236142
• 关键词: data collection methodology /evaluation; depression; functional ability; health education; human data; human population study; human subject; injury /disease stressor; interview; longitudinal human study; patient /disease registry; posttraumatic stress disorder; prognosis; psychological adaptation; psychological stressor; psychosocial rehabilitation; rehabilitation; social support network; socioeconomics; trauma

Little is known about the degree of disability, quality of life, and psychological well-being after major trauma. This prospective cohort study will determine the incidence and determinants of functional limitation after major trauma. Using the computerized San Diego County Regional Trauma System Registry (TREG) trauma patient data base (Appendix I), we propose to determine the incidence and predictors of functional limitation after major trauma in approximately 1200 men and women admitted prospectively to the University of California San Diego (UCSD) Trauma Center. Functional limitation after major trauma will be measured using the Quality of Well-being (QWB) scale at four time points; at discharge, and 6, 12, and 18 months after discharge. Multiple putative predictors of functional limitation after major trauma that will be determined include: (1) injury severity and body area(s) injured, (2) clinical course and treatment of the trauma, (3) sociodemographic characteristics, (4) social support and (5) post-injury psychological sequelae including depression and post-traumatic stress disorder. The prospective epidemiologic study will allow us to determine not only the incidence of functional limitation after major trauma but also the strength and independence of individual predictors of functional limitation. In addition we will be able to determine whether any combination(s) of patient attributes identifies those ag greatest risk so that these patients can be targeted for appropriate intervention. This information will help facilitate appropriate interventions for trauma patients dependent on their predictors of functional limitation.

关于残疾，生活质量和 重大创伤后的心理健康。 这个前瞻性队列 研究将确定功能的发生率和决定因素 重大创伤后的限制。 使用计算机化的圣地亚哥县 区域创伤系统注册中心（TREG）创伤患者数据库（附录 i），我们建议确定功能的发病率和预测因子 大约1200名男性和女人的重大创伤后的限制 前景进入加利福尼亚大学圣地亚哥分校（UCSD） 创伤中心。 重大创伤后的功能限制将使用 福祉质量（QWB）在四个时间点上；出院时 出院后的6、12和18个月。 重大创伤后功能限制的多重推定预测指标 这将确定包括：（1）伤害严重程度和身体区域 受伤，（2）创伤的临床和治疗，（3） 社会人口统计学特征，（4）社会支持和（5）伤害后 心理后遗症，包括抑郁和创伤后压力 紊乱。 前瞻性流行病学研究将使我们不仅确定 重大创伤后功能限制的发生率，但也 功能个体预测指标的力量和独立性 局限性。 另外，我们将能够确定是否有 患者属性的组合确定了那些最大的风险 这样这些患者可以针对适当的干预。 此信息将有助于促进适当的干预措施 创伤患者取决于其功能限制的预测因素。