INTERNATIONAL PROGRAM ON CHEMICAL SAFETY

国际化学品安全计划

• 批准号: 3551177
• 负责人: THRESSA DAMSTRA
• 金额: $ 72.7万
• 依托单位: WORLD HEALTH ORGANIZATION
• 依托单位国家: 美国
• 财政年份: 1980
• 资助国家: 美国
• 起止时间: 1980-09-26 至 1992-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3551177
• 关键词: World Health Organization; air pollution control; carcinogen testing; chemical carcinogen; chemical hypersensitivity; disease /disorder proneness /risk; education evaluation /planning; environmental health; environmental toxicology; epidemiology; food additives; human ecology; industrial waste; international cooperation; international health /scientific organization; monograph; mutagen testing; neurotoxins; occupational hazard; pesticide biological effect; poison control; renal toxin; teratogens; toxicant screening; toxicology information system; training; water pollution control; water quality

As a cooperative venture of the United Nations Environment Programme (UNEP), the International Labour Organization (ILO) and the World Health Organization (WHO), the International Programme on Chemical Safety (IPCS) continues to be managed by WHO through a Central Unit located in the WHO Division of Environmental Health. The Food and Agricultural Organization (FAO) collaborates with IPCS in the Joint Expert Committee on Food Additives (JECFA) and the Joint Meeting on Pesticide Residues (JMPR). The goal of IPCS is to assist Member States in developing scientifically based chemical safety programmes to protect human health and the environment. Objectives in summary are: (1) carry out and disseminate scientific evaluations on the effects of chemicals on human health and the environment, (2) promote development, improvement, validation, and use of methods suitable for evaluation of risks and hazards from chemicals, (3) promote technical cooperation between Member States, (4) promote effective international cooperation regarding chemical emergencies and accidents, (5) support national programmes for prevention and treatment of chemical poisonings, and (6) promote training and development of manpower. Work will be carried out by a network of participating national and international institutions (IRPTC/UNEP, IARC), non-governmental organizations and consultants. Work is reviewed and coordinated by technical secretariat within IPCS/Central Unit. Over the next 3 years, IPCS plans to: complete the evaluation for health and environmental effects of approximately 90-100 new chemicals and complete updating of 4 previously published documents; international chemical safety cards on about 700 chemicals will be prepared and approximately 120 chemicals will be evaluated by JECFA and JMPR. Three updates will be prepared on the computerized register of chemicals under test and chemical reviews. In methodology, complete monographs on Effects of Chemicals on Aged Populations, Assessment of Risk from Chemical Exposure and Nephrotoxicity. Preparation of an updated monograph on methods of toxicity testing to be initiated as well as preparation of reports on biomarkers in risk assessment, immunotoxicity, chemicals and aging, ecosystem risk assessment procedures and in vitro toxicity tests. Complete initial phases of collaborative study on plant assays and the study of short-term genotoxicity test on mixtures. Neurotoxicity and immunotoxicity collaborative studies will be in final stages of completion. Using material available from US agencies; training materials to be developed for use internationally in chemical safety courses.

作为联合国环境规划署的合作企业 （环境署）、国际劳工组织（ILO）和世界卫生组织 组织（WHO）、国际化学品安全规划（IPCS） 继续由世卫组织通过设在世卫组织内的中央单位进行管理 环境卫生司。 粮食及农业组织 （粮农组织）与国际化学品安全方案在食品联合专家委员会中合作 添加剂 (JECFA) 和农药残留联席会议 (JMPR)。 这 IPCS 的目标是协助成员国制定基于科学的 保护人类健康和环境的化学品安全计划。 总体目标是： (1) 开展和传播科学 化学品对人类健康影响的评估 环境，(2) 促进开发、改进、验证和使用 适用于评估化学品风险和危害的方法，(3) 促进成员国之间的技术合作，（4）促进有效 关于化学紧急情况和事故的国际合作，(5) 支持国家化学品预防和处理计划 (6) 促进人力资源的培训和发展。 工作 将由参与的国家和地区网络进行 国际机构（IRPTC/UNEP、IARC）、非政府组织 组织和顾问。 工作由以下人员审查和协调 IPCS/中央单位内的技术秘书处。 未来3年， IPCS 计划： 完成健康和环境评估 约 90-100 种新化学品的影响，并完成 4 种化学品的更新 先前发表的文件；国际化学品安全卡 将准备约700种化学品，并将约120种化学品 由 JECFA 和 JMPR 进行评估。 将准备三项更新 受试化学品和化学品审查的计算机化登记。 在 方法论，关于化学品对老年人的影响的完整专着 人群，化学品暴露和肾毒性风险评估。 编写关于毒性测试方法的更新专着 启动并准备有关风险生物标志物的报告 评估、免疫毒性、化学品和老化、生态系统风险评估 程序和体外毒性试验。 完成初始阶段 植物分析和短期研究的合作研究 混合物的遗传毒性测试。 神经毒性和免疫毒性 合作研究将进入最后完成阶段。 使用 可从美国机构获得的材料；拟开发的培训材料 在国际化学品安全课程中使用。