Yeast-based solutions for sustainable Aviation Fuels (YAF)

基于酵母的可持续航空燃料解决方案 (YAF)

• 批准号: EP/Y031881/1
• 负责人: Rodrigo Ledesma Amaro
• 金额: $ 66.43万
• 依托单位: Imperial College London
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2023
• 资助国家: 英国
• 起止时间: 2023 至 无数据
• 项目状态: 未结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FY031881%2F1
• 关键词: Yeast; based; solutions; sustainable; Aviation

Sustainable aviation fuels (SAF) are the only short-term alternative to fossil fuels in aviation. Considering the increased number of passengers forecasted in the near future, a massive increased in SAF production has been estimated in the years to come. To fulfill this increase in demand, the combination of existing and new renewable production chains is needed. Current SAF-producing pathways are at different levels of maturity, implementation or even commercialization. However, lowering the cost and supply chain development are key challenges for commercial-scale SAF deployment. Using biowastes as feedstock for SAF is challenging but necessary to make SAF competitive with fossil fuels. In this context, yeasts may be key players to generate economically-viable SAF intermediates (terpenes or fatty acids (FA)) in an environmentally-friendly way from biowaste. This SAF production by biological means is very new and presents a lot of remaining challenges and training gaps that have to be addressed. YAF research programme aims at; i) producing carbon sources from biowastes, ii) developing new yeast cell factories to produce SAF, iii) designing new bifunctional catalysts, iv) achieving efficient strategies for FA/terpenes extraction, and v) creating robust framework tailored to the scaling-up methodologies and life-cycle sustainability assessment of different SAF producing routes, which will support decisionmaking. To achieve this, the right integration of biology, biotechnology, chemical engineering and environmental sciences will be required. Thus, the prime training/networking aim of YAF is to train the next generation of researchers in a highly interdisciplinary and intersectorial research environment such that they can soundly address upcoming challenges concerning production yeast based SAF. YAF has been designed to strengthen European research and innovation, enhancing research visibility and generating a critical mass to address European (and global) challenges

可持续航空燃料（SAF）是航空领域化石燃料的唯一短期替代品。考虑到预计不久的将来乘客数量会增加，预计未来几年 SAF 产量将大幅增加。为了满足需求的增长，需要将现有的和新的可再生生产链结合起来。目前的 SAF 生产途径处于不同的成熟度、实施甚至商业化水平。然而，降低成本和供应链发展是商业规模SAF部署的关键挑战。使用生物废物作为 SAF 的原料具有挑战性，但对于使 SAF 与化石燃料竞争是必要的。在这种情况下，酵母可能是以环保方式从生物废物中生产经济可行的 SAF 中间体（萜烯或脂肪酸 (FA)）的关键参与者。这种通过生物手段生产 SAF 的方法是非常新颖的，并且存在许多必须解决的挑战和培训差距。 YAF 研究计划旨在： i) 从生物废物中生产碳源，ii) 开发新的酵母细胞工厂来生产 SAF，iii) 设计新的双功能催化剂，iv) 实现 FA/萜烯提取的有效策略，v) 创建适合放大方法的稳健框架以及不同 SAF 生产路线的生命周期可持续性评估，这将为决策提供支持。为了实现这一目标，需要正确整合生物学、生物技术、化学工程和环境科学。因此，YAF 的主要培训/网络目标是在高度跨学科和跨部门的研究环境中培训下一代研究人员，以便他们能够妥善应对基于酵母的 SAF 生产即将面临的挑战。 YAF 旨在加强欧洲的研究和创新，提高研究的知名度并产生足够的力量来应对欧洲（和全球）的挑战