STRUCTURE OF NATURAL PRODUCTS USING INSTRUMENTAL METHODS

使用仪器方法研究天然产物的结构

• 批准号: 3779520
• 负责人: H M FALES
• 金额: --
• 依托单位: NATIONAL HEART, LUNG, AND BLOOD INSTITUTE
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/3779520
• 关键词: RNA; biological products; chemical structure function; chemical synthesis; gas chromatography mass spectrometry; lactones; liquid chromatography; maltose; sugar phosphates

The structure of a new maltose phosphate arising from the action of oral bacteria has been elucidated and partially synthesized. A substance present in the bedding of hamsters used in supplying blood to malaria mosquitos has been found to be fatal to the mosquitos. Investigations using solvent partition and GC-MS are underway to determine its nature and the nature of the compound responsible for exflagellation in Anopheles species. A possible novel function for RNA has been found: the polymerization of macrocyclic lactones used by Colletes thoracicus.

由口服作用引起的新麦芽糖磷酸盐的结构 细菌已被阐明并部分合成。 一种物质 存在于用于向疟疾提供血液的仓鼠的床上用品中 已经发现蚊子对蚊子致命。 调查 使用溶剂分区和GC-MS来确定其性质 以及造成超氟化物的化合物的性质 肛门物种。 发现了RNA的新功能： Colletes Thoracicus使用的大环内酯的聚合。