PEDIATRIC ONCOLOGY GROUP - OPERATIONS OFFICE

儿科肿瘤组 - 运营办公室

• 批准号: 3557135
• 负责人: TERESA J. VIETTI
• 金额: $ 98.59万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1981
• 资助国家: 美国
• 起止时间: 1981-01-01 至 1990-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3557135
• 关键词: catecholamines; child (0-11); cooperative study; cytogenetics; histopathology; human subject; human therapy evaluation; immunogenetics; neoplasm /cancer chemotherapy; neoplasm /cancer epidemiology; neoplasm /cancer immunotherapy; neoplasm /cancer radiation therapy; neoplasm /cancer surgery; neuroblastoma; pediatric neoplasm /cancer

The Pediatric Oncology Group (POG) is composed of 37 institutions and 21 affiliate institutions who have pooled their patient resources and scientific expertise to study the natural history of childhood cancer, to develop effective therapeutic regimens and to develop clinical trials of new therapeutic agents in children with cancer. There are 637 member investigators which includes pediatric oncologists, pathologists, surgeons, radiation therapists, radiologists, epidemiologists, neurologists, cytogeneticists, immunologists, pharmacologists, psychiatrists and statisticians. Reference laboratories for immunology, steroid receptors, cytogenetics, bone marrow culture, HLA typing, immunophenotyping, pharmacology studies and catacholamine levels are established at various member institutions to further investigate the natural history of childhood cancer and to investigate factors which may be of importance in prognosis. The Group Chairman provides executive and scientific guidance and is responsible for creating an environment which will encourage the development of research protocols of the highest scientific merit. The specific objective of the POG Operations Office is to provide the facilities and staff that serve as the central office for collection, processing, classification and distribution of essential and vital data and information that is necessary for member investigators to participate in the research activities of the Group. This office will prepare, edit, process and distribute POG protocols from the initial concept to activation and will monitor the progress of studies during their active phase as well as preparation of manuscripts for publication. It will be responsible for arranging, conducting and supervising POG meetings and generating and distribution minutes of these meetings. This office will arrange and coordinate quality control institutional audits. All of the activity of the Operations Office will be coordinated with that of the Statistical Office. This application is requesting continued funding for the POG Operations Office and includes budgets for standing committees and reference laboratories.

小儿肿瘤学组（POG）由37个机构和21个组成 汇集了患者资源的会员机构 研究儿童癌症的自然历史的科学专业知识， 制定有效的治疗方案并开发 癌症儿童的新治疗剂。 有637名成员 研究人员包括儿科肿瘤学家，病理学家，外科医生， 放射治疗师，放射学家，流行病学家，神经病学家， 细胞遗传学家，免疫学家，药理学家，精神科医生和 统计学家。 免疫学，类固醇受体的参考实验室， 细胞遗传学，骨髓培养，HLA打字，免疫表型， 在各种 会员机构进一步研究童年的自然历史 癌症和研究可能在预后可能很重要的因素。 小组主席提供了执行和科学指导，是 负责创造一个将鼓励的环境 制定最高科学功绩的研究方案。 POG运营办公室的具体目标是提供 担任中央办公室的设施和员工， 基本和重要数据的处理，分类和分布以及 成员调查人员参与必要的信息 小组的研究活动。 该办公室将从 激活的最初概念，并将监测研究的进度 在他们的主动阶段以及准备手稿 发布。 它将负责安排，进行和 监督POG会议，并生成和分发这些 会议。 该办公室将安排和协调质量控制 机构审核。 运营办公室的所有活动将是 与统计办公室的协调。 该申请要求继续为POG操作提供资金 办公室，包括常设委员会的预算和参考 实验室。