PEDIATRIC ONCOLOGY GROUP--OPERATIONS OFFICE

儿科肿瘤组--运营办公室

• 批准号: 3557145
• 负责人: TERESA J. VIETTI
• 金额: $ 122.81万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1981
• 资助国家: 美国
• 起止时间: 1981-01-01 至 1991-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3557145
• 关键词: catecholamines; child (0-11); cooperative study; cytogenetics; histopathology; human subject; human therapy evaluation; immunogenetics; neoplasm /cancer chemotherapy; neoplasm /cancer epidemiology; neoplasm /cancer immunotherapy; neoplasm /cancer radiation therapy; neoplasm /cancer surgery; neuroblastoma; pediatric neoplasm /cancer

The Pediatric Oncology Group (POG) is composed of 37 institutions and 21 affiliate institutions who have pooled their patient resources and scientific expertise to study the natural history of childhood cancer, to develop effective therapeutic regimens and to develop clinical trials of new therapeutic agents in children with cancer. There are 637 member investigators which includes pediatric oncologists, pathologists, surgeons, radiation therapists, radiologists, epidemiologists, neurologists, cytogeneticists, immunologists, pharmacologists, psychiatrists and statisticians. Reference laboratories for immunology, steroid receptors, cytogenetics, bone marrow culture, HLA typing, immunophenotyping, pharmacology studies and catacholamine levels are established at various member institutions to further investigate the natural history of childhood cancer and to investigate factors which may be of importance in prognosis. The Group Chairman provides executive and scientific guidance and is responsible for creating an environment which will encourage the development of research protocols of the highest scientific merit. The specific objective of the POG Operations Office is to provide the facilities and staff that serve as the central office for collection, processing, classification and distribution of essential and vital data and information that is necessary for member investigators to participate in the research activities of the Group. This office will prepare, edit, process and distribute POG protocols from the initial concept to activation and will monitor the progress of studies during their active phase as well as preparation of manuscripts for publication. It will be responsible for arranging, conducting and supervising POG meetings and generating and distribution minutes of these meetings. This office will arrange and coordinate quality control institutional audits. All of the activity of the Operations Office will be coordinated with that of the Statistical Office. This application is requesting continued funding for the POG Operations Office and includes budgets for standing committees and reference laboratories.

儿科肿瘤学组 (POG) 由 37 个机构和 21 个 汇集患者资源的附属机构 研究儿童癌症自然史的科学专业知识 制定有效的治疗方案并开展临床试验 儿童癌症的新治疗药物。 现有会员637人 研究人员包括儿科肿瘤学家、病理学家、外科医生、 放射治疗师、放射科医生、流行病学家、神经科医生、 细胞遗传学家、免疫学家、药理学家、精神病学家和 统计学家。 免疫学、类固醇受体参考实验室、 细胞遗传学、骨髓培养、HLA 分型、免疫表型分析、 药理学研究和儿茶酚胺水平是在不同的 成员机构进一步研究儿童自然史 癌症并研究对预后可能重要的因素。 集团主席提供行政和科学指导， 负责创造一个鼓励的环境 制定具有最高科学价值的研究方案。 POG 运营办公室的具体目标是提供 作为收集中心办公室的设施和工作人员， 基本和重要数据的处理、分类和分发以及 成员调查员参与所需的信息 集团的研究活动。 该办公室将准备、编辑、处理和分发 POG 协议 激活的初步概念并将监测研究进展 在他们的活跃阶段以及准备手稿的阶段 发布。 它将负责安排、进行和 监督 POG 会议并生成和分发这些会议记录 会议。 该办公室将安排和协调质量控制 机构审计。 运营办公室的所有活动都将 与统计局协调。 此申请请求为 POG 运营持续提供资金 办公室并包括常设委员会的预算和参考 实验室。