NEW ENGLAND PEDIATRIC ONCOLOGY CONSORTIUM

新英格兰儿科肿瘤学联盟

• 批准号: 3557063
• 负责人: EDWIN N FORMAN
• 金额: $ 8.48万
• 依托单位: RHODE ISLAND HOSPITAL
• 依托单位国家: 美国
• 财政年份: 1981
• 资助国家: 美国
• 起止时间: 1981-01-01 至 1990-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3557063
• 关键词: Hodgkin's disease; asparaginase; cancer rehabilitation mental health service; child (0-11); cis platinum compound; combination cancer therapy; combination chemotherapy; cooperative study; dexamethasone; drug adverse effect; human subject; human therapy evaluation; lymphocytic leukemia; lymphoma; methotrexate; neoplasm /cancer chemotherapy; neoplasm /cancer radiation therapy; pediatric neoplasm /cancer; pediatric pharmacology; prednisone; retinoblastoma; vincristine

The objective of this project is the continued development and enhanced productivity of an efficiently functioning consortium of four New England pediatric cancer centers (Brown University/Rhode Island Hospital; Dartmouth-Hitchcock Medical Center-Norris Cotton Cancer Center; Harvard University/Massachusetts General Hospital; University of Vermont/Medical Center Hospital-Vermont Regional Cancer Center) for the purpose of: A. Contributing to the understanding and treatment of childhood malignancies through: 1. Input into national cooperative studies through active membership in the Pediatric Oncology Group (POG): a. Patient Accrual: Achieve significant number and quality of patient entries on protocols. b. Study Development and Evaluation: Assist in the development of new protocols through committee membership, institution review of proposed protocol designs, critical analysis of study results, and proposal of new protocols for POG implementation based on NEPOC studies (including identification of occult CNS leukemia through new laboratory methodology). 2. Stimulation and facilitation of cooperative efforts within NEPOC in studies of joint interest in the area of childhood malignancies, in particular toward developing potential pilot studies for POG. B. Enhancement of the care of children with cancer in the geographical areas served by the NEPOC member institutions through: 1. Assuring comprehensive and modern management of childhood malignancies as a benefit of membership in a national cooperative pediatric oncology study group; 2. Sharing the staff expertise and investigative facilities at each of the NEPOC centers; 3. Joint efforts in the promotion of education of the local community in the area of cancer in children. Through a centralized administration, this Consortium will integrate the activities and resources (staff, investigative facilities, patients) at each of the four member institutions into a single program aimed at achieving these goals.

该项目的目的是持续开发和增强 有效运作的四个新英格兰联盟的生产力 小儿癌症中心（布朗大学/罗德岛医院； 达特茅斯 - 希区柯克医疗中心 - 诺里斯棉花癌中心；哈佛大学 大学/马萨诸塞州综合医院；佛蒙特大学/医学 中心医院范围区域癌症中心）的目的： A.为童年的理解和治疗做出贡献 通过： 1。通过积极的成员资格对国家合作研究的投入 小儿肿瘤学组（POG）： 一个。应计患者：获得大量患者的数量和质量 协议上的条目。 b。研究开发和评估：协助开发新的 通过委员会会员资格，拟议的机构审查 协议设计，研究结果的批判性分析以及新的建议 基于NEPOC研究的POG实施方案（包括 通过新的实验室方法论鉴定神秘中枢神经系统白血病）。 2。刺激和促进NEPOC中合作努力 研究儿童恶性肿瘤领域的共同兴趣， 特别是为POG开发潜在的试点研究。 B.在地理学中增强癌症儿童的护理 NEPOC会员机构为以下区域服务的地区： 1。确保对儿童恶性肿瘤的全面和现代管理 作为国家合作儿科肿瘤学成员的好处 研究小组； 2。分享每个人的员工专业知识和调查设施 NEPOC中心； 3。促进当地社区教育的共同努力 儿童癌症区域。 通过集中管理，该财团将整合 活动和资源（工作人员，调查设施，患者） 四个成员机构中的每一个都涉及一个针对的计划 实现这些目标。