SECONDARY PREVENTION WITH HIV+ YOUTHS IN SF LA AND NYC

旧金山洛杉矶和纽约市艾滋病毒青少年的二级预防

• 批准号: 3567079
• 负责人: Mary Jane Rotheram-Borus
• 金额: $ 27.78万
• 依托单位: NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC
• 依托单位国家: 美国
• 财政年份: 1991
• 资助国家: 美国
• 起止时间: 1991-09-30 至 1995-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3567079
• 关键词: AIDS education /prevention; HIV infections; adolescence (12-20); behavior modification; behavior test; communicable disease control; communicable disease transmission; cooperative study; culture; disease /disorder proneness /risk; drug abuse; geographic site; health behavior; health care model; human subject; pediatric AIDS; psychological adaptation; psychological values; role model; sex behavior; social adjustment; social support network; substance abuse related disorder; urban area

The goal of this project is to evaluate the effectiveness of an intensive AIDS prevention program to eliminate and/or reduce risk acts that will transmit the HIV virus from 540 HIV+ youths aged 14-20 from three AIDS epicenters (Los Angeles [LA], New York [NY], and San Francisco [SF]). Changes in sexual and substance abuse risk acts will be monitored over 18 months (assessed at intake, 2, 4, 6, 12, and 18 months) as youths are randomly assigned within each site to one of the two intervention conditions designed on the AIDS Risk Reduction Model (ARRM): 1) a core module of 15-20 hours of AIDS prevention reflecting the current best intervention practice; or 2) three modules (the core module, a specialized HIV+ module, and a booster module) of 15-20 hours each, tailored specifically for HIV+ youths. There are few guidelines on how to adopt the ARRM for HIV+ youths, as the data are very limited. Therefore, prior to initiating the prevention trial, an ethnographic study will document the physical, social, and interpersonal contexts that characterize the lives of HIV+ youths and the impact of seropositivity on HIV+ youths as we observe how youths learn to adapt to their serostatus over one year. Differential effectiveness will be examined as a function of three sets of mediating factors: background characteristics (e.g., gender, sexual orientation), acquisition of the skills and norms taught in the intervention, and site. Finally, we will examine whether reductions in HIV risk acts are associated with changes in physical health and other problem behaviors (e.g., school and conduct problems, suicidality).

该项目的目的是评估密集型的有效性 艾滋病预防计划，以消除和/或减少将 从三个艾滋病的14-20岁的540名HIV+青年中传播HIV病毒 中心（洛杉矶[LA]，纽约[纽约]和旧金山[SF]）。 性和滥用药物滥用风险行为的变化将在18岁以上监控 年轻人是年轻人的月份（在摄入量，2、4、6、12和18个月） 在每个站点中随机分配给两个干预措施之一 在艾滋病风险降低模型（ARRM）上设计的条件：1）核心 预防艾滋病的15-20小时的模块反映了当前最佳 干预实践；或2）三个模块（核心模块，一个专业的模块 HIV+模块和助推器模块）每个15-20小时，量身定制 专门针对艾滋病毒+青年。 关于如何采用的指南很少 艾滋病毒+年轻人的ARRM，因为数据非常有限。 因此，之前 发起预防试验，民族志研究将记录 身体，社会和人际背景的特征 当我们观察到的HIV+青年以及血清阳性对艾滋病毒+青年的影响 年轻人如何在一年内学会适应自己的血清。 微分 有效性将作为三组中介的函数检查 因素：背景特征（例如性别，性取向）， 在干预和现场教授的技能和规范的获取。 最后，我们将检查艾滋病毒风险行为的减少是否与 随着身体健康和其他问题行为的变化（例如，学校 并进行问题，自杀）。