Multi-User Equipment to Refresh Underpinning Analytical Capabilities at the University of Warwick

多用户设备刷新华威大学的基础分析能力

• 批准号: EP/P030572/1
• 负责人: Pamela Thomas
• 金额: $ 254.61万
• 依托单位: University of Warwick
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2017
• 资助国家: 英国
• 起止时间: 2017 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=EP%2FP030572%2F1
• 关键词: Multi; User; Equipment; Refresh; Underpinning

Our ability to rapidly and routinely obtain information about the composition, structure, morphology and function of molecules, materials and devices produced by man or by nature is central to many advances and breakthroughs in the Engineering and Physical Sciences (EPS). Therefore, the main aim of this proposal is to replace and upgrade obsolete or near end-of-life underpinning, multi-user equipment within our mass spectrometry, microscopy and device characterisation Facilities/Research Technology Platforms (RTP), to ensure that researchers at Warwick (UW) have access to a state-of-the-art Analytical Science (AS) infrastructure. UW's long-term excellence in AS is firmly rooted in strategic investment (e.g. people, equipment, infrastructure, training, etc.) in this underpinning field. The AS equipment requested includes:1) Four instruments for our Mass Spectrometry (MS) Facility, including an Inductively Coupled Plasma Mass Spectrometer, Gas Chromatography Quadrupole Mass Spectrometer, MicroTOF Focus and 3D ion trap Mass Spectrometer, which will increase both our analytical capacity and level of sensitivity.2) Three core workhorse microscopy devices from within our RTP programme: including a Transmission Electron Microscope, Atomic Force Microscope, and confocal Raman; allowing us to increase both our core analysis capacity through higher speed imaging, and improved image resolution.3) A Parameter Analyser and Probing System to be hosted within the University's Power Electronic Characterisation suite (PEATER), to enable both greater processing capacity and the analysis of devices at higher voltages and currents.The proposed AS equipment will be used to facilitate and strengthen a wide range of EPS research at UW, that falls within EPSRC's strategic remit and is comprehensively aligned to the research strategy of the University; contributing to core themes within the University's 'Global Research Priorities' (GRPs) including Energy, Innovative Manufacturing, Science and Technology for Health, and Materials. The new AS equipment will underpin the research of >50 academic groups from across four key departments (Chemistry, Physics, Engineering and WMG) within the Faculty of Science, working in diverse fields, including: catalysis, chemical and synthetic biology, energy materials, manufacturing, medical imaging, nanoparticles, nanocomposites, polymer materials, power electronics, semiconductors, structural engineering, synthetic organic and coordination chemistry. This investment in state-of-the art equipment will also be fundamental to facilitating the training of many M-Level undergraduates, MSc and PhD students, and early career researchers in cutting-edge AS techniques. Each Facility/RTP has well established programmes of user training and support, and these are open to all UW student and staff users. This training will also be offered to external academics and industry partners. UW is committed to ensuring that the equipment requested is effectively managed and maintained, and that usage is maximised across the University and by external research partners. The equipment will either be managed through shared Facilities (MS and PEATER), or through the appropriate RTP (Electron Microscopy and proposed Optical Spectroscopy) to which UW has provided significant investment. Overall, UW's contribution to its RTPs totals more than £8.84M (staff, equipment, maintenance and consumables) since their inception in 2014. Access will be advertised internally through the GRPs, and externally through Warwick Scientific Services (WSS) - a centre of excellence based at UW, delivering cutting-edge world class scientific services, technical measurement solutions, innovative translational research, and knowledge and training services to businesses that could benefit from expertise and instrumentation. It will also be listed on equipment.data, a national equipment sharing portal.

我们快速，常规获取有关人类或本质上生产的分子，材料和设备的组成，结构，形态和功能的信息对于工程和物理科学（EPS）的许多进步和突破至关重要。因此，该提案的主要目的是在我们的质谱，显微镜和设备表征设施/研究技术平台（RTP）中替换和升级过时的或接近寿命的基础，多用户设备（RTP），以确保Warwick（UW）的研究人员能够访问一项正式的现有分析科学（AS）基础设施。 UW在此基础领域中的战略投资（例如人，设备，基础设施，培训等）的长期卓越基础。所需的AS设备包括：1）我们质谱（MS）设施的四种仪器，包括电感耦合等离子体质谱仪，气体色谱级质谱仪，缩影焦点和3D离子诱捕质量光谱仪，这将增加我们的分析能力和敏感性。原子力显微镜和共焦拉曼； allowing us to increase Both our core analysis capacity through higher speed imaging, and improved image resolution.3) A Parameter Analyser and Probing System to be hosted within the University's Power Electronic Characterisation Suite (PEATER), to enable both greater processing capacity and the analysis of devices at higher voltages and currents.The proposed AS equipment will be used to facilitate and strengthen a wide range of EPS research at UW, that falls within EPSRC's strategic remit and is全面地与大学的研究策略保持一致；在大学的“全球研究优先事项”（包括能源，创新制造，健康和材料的科学和技术）中促进了核心主题。 The new AS equipment will underpin the research of >50 academic groups from across four key departments (Chemistry, Physics, Engineering and WMG) within the Faculty of Science, working in divers fields, including: catalysis, chemical and synthetic biology, energy materials, manufacturing, medical imaging, nanoparticles, nanocomposites, polymer materials, power electronics, semiconductors, structural engineering, synthetic organisation and coordination chemistry.这项对最先进设备的投资也将是支持许多M级本科生，MSC和博士生的培训以及早期职业研究人员的培训。每个设施/RTP都有良好的用户培训和支持计划，并且对所有UW学生和员工用户都开放。该培训还将提供给外部学者和行业合作伙伴。 UW致力于确保所要求的设备有效地管理和维护，并在整个大学和外部研究合作伙伴中最大化用法。该设备将通过共享设施（MS和Peater）进行管理，或者通过适当的RTP（电子显微镜和提议的光学光谱）进行管理，UW为其提供了大量投资。总体而言，自2014年成立以来，UW对其RTP的贡献总计超过884万英镑（员工，设备，维护和消耗品）。访问将通过GRP内部进行广告广告，并通过Warwick Scientific Services（WSS）（WSS）（WSS）（WSS）（WSS） - 基于卓越的AT UW中心，从而提供了UW，从而提供尖端的世界阶级科学服务，从而使技术型，技术性的研究，技术性的研究，创新，创新，创新，创新，创新，创新，创新，创新，创新，创新，创新，创新，创新，创新，创新，创新，创新，创新，创新，创新，创新，创新，创新，创新，创新，创新，创新，创新，创新，创新，创新，创新，创新，创新，创新，创新，创新，创新，创新的效果，创新，创新的效果。专业知识和仪器。它也将在设备上列出。Data，国家设备共享门户网站。

项目成果

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Metallodrugs are unique: opportunities and challenges of discovery and development.

• DOI: 10.1039/d0sc04082g
• 发表时间: 2020-11-12
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• 作者: Anthony EJ;Bolitho EM;Bridgewater HE;Carter OWL;Donnelly JM;Imberti C;Lant EC;Lermyte F;Needham RJ;Palau M;Sadler PJ;Shi H;Wang FX;Zhang WY;Zhang Z
• 通讯作者: Zhang Z

Experimental and theoretical evidence for unprecedented strong interactions of gold atoms with boron on boron/sulfur-doped carbon surfaces

• DOI: 10.1039/d3na00956d
• 发表时间: 2023-12
• 期刊: Nanoscale Advances
• 影响因子: 4.7
• 作者: Samya Banerjee;J. Wolny;Mohsen Danaie;Nicolas P. E. Barry;Yisong Han;Houari Amari;Richard Beanland;Volker Schünemann;Peter J Sadler

Metallation-induced heterogeneous dynamics of DNA revealed by single-molecule FRET.

• DOI: 10.1002/chem.202000458
• 发表时间: 2020-01
• 期刊: Chemistry
• 作者: Raul Berrocal-Martin;C. Sanchez‐Cano;Cookson K. C. Chiu;R. J. Needham;P. Sadler;S. Magennis

Dual-action platinum(II) Schiff base complexes: Photocytotoxicity and cellular imaging

• DOI: 10.1016/j.poly.2019.04.024
• 发表时间: 2019-11
• 期刊: Polyhedron
• 影响因子: 2.6
• 作者: Samya Banerjee;Miles S Capper;G. Clarkson;Huaiyi Huang;P. Sadler