BIOMEDICAL RESEARCH IN THE CARIBBEAN ENVIRONMENT

加勒比环境中的生物医学研究

• 批准号: 3513662
• 负责人: MELEDATH E GOVINDAN
• 金额: $ 21.56万
• 依托单位: UNIVERSITY OF THE VIRGIN ISLANDS
• 依托单位国家: 美国
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-09-30 至 1995-08-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3513662
• 关键词: Caribbean islands; minority institution research support

The general objective of the proposed University of the Virgin Islands MBRS program, Biomedical Research in the Caribbean Environment (BRCE), is to continue to provide opportunities for the faculty and talented minority students to conduct biomedically significant research. The proposal includes four research projects and a research enrichment component. The first research project (Project #2), a new proposal, will examine the nature and function of acyl carrier proteins that are involved in lipid biosynthesis in coelenterates and their symbiotic dinoflagellate algae. This will provide a model system for understanding the various aspects of lipid biosynthesis in higher plants and animals, including humans. The second project (Project #3) will continue to involve isolation, characterization, and bioassay of pharmacologically important secondary metabolites from marine organisms, such as algae and soft corals, which are abundant in the shallow-water habitats of the Caribbean. The third project (Project #5) will continue to test several hypotheses on the function of these secondary metabolites on the organisms in order to develop predictive theories as to where, when, and in what concentration biomedically active substances will be found in marine organisms. The fourth project (project #4), revision of an approved (but not funded) supplemental proposal, will consider hospital admission decisions and course of treatment as predictors of psychiatric patient outcomes and would permit development of an ongoing research program in applied psychology at UVI. The research enrichment will continue to provide opportunities for faculty and students to learn new techniques and developments by attending off-campus conferences as well as on-campus seminars, workshops, and informal discussions by visiting scientists (including minority role models). Through the proposed activities, the students and faculty will continue to participate in scholarly research. They will interact and collaborate with scientists from Puerto Rico and in the U. S. mainland. The most significant features of the proposed program are the inter-relatedness of three of the research projects, the close collaboration among faculty from biology, chemistry and marine biology, and the attempt to involve a faculty member and two students from psychology in biomedical research.

拟议的维尔京群岛大学 MBRS 的总体目标 加勒比环境生物医学研究 (BRCE) 计划旨在 继续为教师和少数有才华的人提供机会 学生进行具有生物医学意义的研究。 提案 包括四个研究项目和一个研究丰富部分。 这 第一个研究项目（项目#2）是一项新提案，将研究 参与脂质的酰基载体蛋白的性质和功能 腔肠动物及其共生甲藻的生物合成。 这将为理解各个方面提供一个模型系统 高等植物和动物（包括人类）的脂质生物合成。 这 第二个项目（项目#3）将继续涉及隔离， 具有药理学重要作用的次级化合物的表征和生物测定 来自海洋生物的代谢物，例如藻类和软珊瑚， 加勒比海浅水生境中资源丰富。 第三个项目 （项目#5）将继续测试关于函数的几个假设 这些生物体的次生代谢物，以便开发预测 关于生物医学活性的地点、时间和浓度的理论 物质将在海洋生物中被发现。 第四个项目（项目 #4)，修订已批准（但未资助）的补充提案，将 将入院决定和治疗过程视为预测因素 精神病患者的结果，并将允许发展一个持续的 UVI 应用心理学研究项目。 研究充实 将继续为教师和学生提供学习的机会 通过参加校外会议了解新技术和发展 作为校园研讨会、讲习班和非正式讨论，通过访问 科学家（包括少数群体的榜样）。 通过拟议的活动，学生和教师将继续 参与学术研究。 他们将与以下人员互动和协作 来自波多黎各和美国大陆的科学家。 最 拟议计划的显着特点是相互关联 其中三个研究项目是来自教职员工之间的密切合作 生物学、化学和海洋生物学，以及让教师参与的尝试 成员和两名从事生物医学研究的心理学学生。