NEW ULTRATHIN ANGIOSCOPE FOR ATHERECTOMY APPLICATIONS

适用于动脉粥样硬化切除术应用的新型超薄血管内窥镜

• 批准号: 3502214
• 负责人: James Castracane
• 金额: $ 4.88万
• 依托单位: INTERSCIENCE, INC.
• 依托单位国家: 美国
• 财政年份: 1992
• 资助国家: 美国
• 起止时间: 1992-05-01 至 1993-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3502214
• 关键词: angiography; artery; bioengineering /biomedical engineering; biomedical equipment development; clinical biomedical equipment; diagnosis procedure safety; diagnostic catheterization; digital imaging; fiber optics; image processing; time resolved data

The long term goal of the research presented in this proposal is to develop a design for innovative imaging instrumentation called the Ultrathin Angioscope for Atherectomy Applications. The imaging device is specifically designed to be utilized by current atherectomy instrumentation in order to provide high resolution, 3-dimensional, real time in vivo monitoring of the procedure. The minute angioscope will be inserted through the guidewire channel of the atherectomy instrument and advanced and retracted as different lumenal views are needed throughout the procedure. The significance of this design is the increased information it will provide to the physician about the conditions of the arterial system in addition to the currently used 2-dimensional angiogram. Specifically, in Phase I, a prototype system will be developed in order to demonstrate the feasibility of the optical principles and the overall system design. Prototype demonstrations will include insertion of the angioscope through an atherocath in order to image model arterial lumens into a CCD camera. Potential applications are widespread for such a minute imaging system. Once developed the system can be used in conjunction with a variety of cardiac instrumentation and procedures, such a balloon angioplasty.

本提案中提出的研究的长期目标是 开发一种创新成像仪器的设计，称为 用于斑块切除术应用的超薄血管镜。成像装置是 专门设计用于当前的斑块旋切术 仪器以提供高分辨率、3维、真实 程序的体内监测时间。微小血管镜将 通过旋切术器械的导丝通道插入并 推进和缩回，因为整个过程中需要不同的管腔视图 程序。这种设计的意义在于增加了 它将向医生提供有关患者状况的信息 动脉系统除了目前使用的二维 血管造影。具体来说，在第一阶段，原型系统将是 开发的目的是为了证明光学的可行性 原理和总体系统设计。原型演示将 包括通过动脉粥样硬化导管插入血管镜，以便 将动脉管腔图像模型传输到 CCD 相机中。潜在应用 对于这样一个微小的成像系统来说是很普遍的。一旦开发出 系统可与多种心脏设备配合使用 仪器和程序，例如球囊血管成形术。