Experimental Equipment Call - University of Leeds
实验设备调用 - 利兹大学
基本信息
- 批准号:EP/M028143/1
- 负责人:
- 金额:$ 469.65万
- 依托单位:
- 依托单位国家:英国
- 项目类别:Research Grant
- 财政年份:2015
- 资助国家:英国
- 起止时间:2015 至 无数据
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
The objective of this proposal is to refresh and update key items of experimental equipment in activities aligned to proven strengths and critical mass in Medical Engineering and Advanced Materials at the University of Leeds.The Institute of Medical and Biological Engineering hosts the largest and most advanced musculoskeletal simulation facility in the world. The new simulators will support three of our strategic research challenges: longer lasting joint replacements; regenerative devices and biological scaffolds for tissue repair; and, advanced simulation systems for virtual analysis and design and preclinical testing. They will deliver enhanced functionality, allowing the development and introduction of SAFER (Stratified Approaches For Enhanced Reliability) simulation methods to address the requirements of stratified and personalized medical devices, biomaterials and scaffolds. The simulators will be used for research into the tribology and wear of artificial joints, validation of novel computational methods for prediction of function, studies of wear debris and supporting biocompatibility research and studies of the tribology of biological scaffolds in natural joints, using recently developed methods.Our research in terahertz (THz) frequency electronics and photonics is internationally leading by any criterion. Much of this activity requires a state-of-the-art and dedicated MBE semiconductor growth system. The new MBE system will allow us to protect the UK's international reputation in this field and, in particular, in the growth and exploitation of THz frequency quantum cascade lasers (QCLs). Over the next five years we will: develop state-of-the-art THz QCLs across the 1-5 THz range, maximizing operating temperature, continuous-wave performance, output power, and gain bandwidth; develop THz QCLs engineered into robust device architectures for use as, for example, local oscillators in earth-observation and planetary science missions; develop compact bench-top QCL-based technologies producing intense, narrowband and precisely controllable pulses for non-linear THz science; and, develop self-organised quantum rod structures for cavity-QED experiments, and new optically-pumped, vertical-cavity surface-emitting room temperature THz lasers.The Leeds Electron Microscopy and Spectroscopy (LEMAS) Centre is a highly successful shared electron microscopy facility. It has high visibility nationally (providing an EPSRC open access scheme for external users since 2008) and internationally (leading the consortium that formed the UK facility at SuperSTEM Daresbury). One of the next great challenges is apply high-resolution imaging and microanalytical techniques to beam sensitive materials, including advanced hybrid materials comprising organic and inorganic components. These are increasingly employed to develop new device and product functionalities. The specification of the new microscope is unique and designed to enable fast mapping of frozen specimens at high accelerating voltage to preserve their chemistry and structure whilst extracting nanostructural information.We are internationally recognised in spintronics and magnetic materials, with recent appointments extending our materials expertise to include organic molecules, piezoelectrics, topological insulators and superconductors. The new deposition tool will ensure we can continue to supply top quality thin film materials to the UK and internationally, as well as underpinning a general theme of spintronic meta-materials. The functional properties of meta-materials emerge through the design and engineering of the constituent material combinations. With our broad background that includes the ability to structure materials at the nanoscale so that cooperative behaviour arises, we will apply this capability to questions in strategic areas such as quantum effects for new technology, beyond CMOS electronics, energy efficient electronics, and new tools for healthcare.
该提案的目的是更新和更新与利兹大学医学工程和先进材料领域已证实的优势和临界质量相一致的活动中实验设备的关键项目。医学和生物工程研究所拥有最大、最先进的肌肉骨骼实验室世界上最先进的模拟设施。新的模拟器将支持我们的三个战略研究挑战:更持久的关节置换术;用于组织修复的再生装置和生物支架;用于虚拟分析和设计以及临床前测试的先进模拟系统。它们将提供增强的功能,允许开发和引入 SAFER(增强可靠性的分层方法)模拟方法,以满足分层和个性化医疗设备、生物材料和支架的要求。该模拟器将用于研究人工关节的摩擦学和磨损,验证用于预测功能的新型计算方法,研究磨损碎片并支持生物相容性研究以及使用最近开发的方法对自然关节中生物支架的摩擦学进行研究.我们在太赫兹(THz)频率电子学和光子学方面的研究无论从任何标准来看都处于国际领先地位。其中大部分活动需要最先进的专用 MBE 半导体生长系统。新的 MBE 系统将使我们能够保护英国在该领域的国际声誉,特别是在太赫兹频率量子级联激光器 (QCL) 的发展和开发方面。在接下来的五年里,我们将: 开发 1-5 THz 范围内最先进的 THz QCL,最大限度地提高工作温度、连续波性能、输出功率和增益带宽;开发太赫兹 QCL,设计成坚固的设备架构,用作地球观测和行星科学任务中的本地振荡器等;开发基于 QCL 的紧凑型台式技术,为非线性太赫兹科学产生强、窄带和精确可控的脉冲;并开发用于腔 QED 实验的自组织量子棒结构,以及新型光泵浦、垂直腔表面发射室温太赫兹激光器。利兹电子显微镜和光谱 (LEMAS) 中心是一个非常成功的共享电子显微镜设施。它在国内(自 2008 年以来为外部用户提供 EPSRC 开放访问方案)和国际上(领导在 SuperSTEM Daresbury 建立英国设施的联盟)具有很高的知名度。接下来的巨大挑战之一是将高分辨率成像和微分析技术应用于光束敏感材料,包括由有机和无机成分组成的先进混合材料。这些越来越多地用于开发新设备和产品功能。新型显微镜的规格是独特的,旨在能够在高加速电压下快速绘制冷冻样本,以保留其化学和结构,同时提取纳米结构信息。我们在自旋电子学和磁性材料领域获得国际认可,最近的任命将我们的材料专业知识扩展到包括有机分子、压电体、拓扑绝缘体和超导体。新的沉积工具将确保我们能够继续向英国和国际供应高质量的薄膜材料,并支撑自旋电子超材料的总体主题。超材料的功能特性是通过组成材料组合的设计和工程而显现出来的。凭借我们广泛的背景,包括在纳米尺度上构造材料以产生合作行为的能力,我们将把这种能力应用于战略领域的问题,例如新技术的量子效应、超越 CMOS 电子学、节能电子学和新工具卫生保健。
项目成果
期刊论文数量(10)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
The influence of simulator input conditions on the wear of total knee replacements: An experimental and computational study.
- DOI:10.1177/0954411916645134
- 发表时间:2016-05
- 期刊:
- 影响因子:0
- 作者:Brockett CL;Abdelgaied A;Haythornthwaite T;Hardaker C;Fisher J;Jennings LM
- 通讯作者:Jennings LM
Influence of hip joint simulator design and mechanics on the wear and creep of metal-on-polyethylene bearings.
- DOI:10.1177/0954411915620454
- 发表时间:2016-05
- 期刊:
- 影响因子:0
- 作者:Ali M;Al-Hajjar M;Partridge S;Williams S;Fisher J;Jennings LM
- 通讯作者:Jennings LM
Simple geometry tribological study of osteochondral graft implantation in the knee.
- DOI:10.1177/0954411917751560
- 发表时间:2018-03
- 期刊:
- 影响因子:0
- 作者:Bowland P;Ingham E;Fisher J;Jennings LM
- 通讯作者:Jennings LM
Influence of conformity on the wear of total knee replacement: An experimental study.
- DOI:10.1177/0954411917746433
- 发表时间:2018-03
- 期刊:
- 影响因子:0
- 作者:Brockett CL;Carbone S;Fisher J;Jennings LM
- 通讯作者:Jennings LM
PEEK and CFR-PEEK as alternative bearing materials to UHMWPE in a fixed bearing total knee replacement: An experimental wear study.
- DOI:10.1016/j.wear.2016.12.010
- 发表时间:2017-03-15
- 期刊:
- 影响因子:0
- 作者:Brockett CL;Carbone S;Fisher J;Jennings LM
- 通讯作者:Jennings LM
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David Hogg其他文献
Transmembrane signalling by interleukin 2.
白细胞介素 2 的跨膜信号传导。
- DOI:
- 发表时间:
1991 - 期刊:
- 影响因子:3.9
- 作者:
Gordon B. Mills;Nan Zhang;Rosemarie Schmandt;Marion Fung;Warner C. Greene;Alan Mellors;David Hogg - 通讯作者:
David Hogg
Cognitive Workflow Capturing and Rendering with On-Body Sensor Networks (COGNITO)
使用体上传感器网络 (COGNITO) 进行认知工作流程捕获和渲染
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
Gabriele Bleser;Luis Almeida;Ardhendu Behera;Andrew Calway;Anthony Cohn;D. Damen;Hugo Domingues;Andrew Gee;Dominic Gorecky;David Hogg;Michael Kraly;Trivisio Prototyping;GmbH;Germany Gustavo;Maçães;Frédéric Marin;Walterio W. Mayol;M. Miezal;K. Mura;Nils Petersen;N. Vignais;Luís Paulo;Santos;G. Spaas;Germany Gmbh;Stricker - 通讯作者:
Stricker
Mutation analysis of the PALB2 cancer predisposition gene in familial melanoma
家族性黑色素瘤PALB2癌易感基因突变分析
- DOI:
- 发表时间:
2011 - 期刊:
- 影响因子:2.2
- 作者:
N. Sabbaghian;N. Sabbaghian;R. Kyle;R. Kyle;A. Hao;David Hogg;M. Tischkowitz;M. Tischkowitz - 通讯作者:
M. Tischkowitz
Chapter 53 – Testicular Cancer
第53章-睾丸癌
- DOI:
10.1016/b978-1-4377-1637-5.00053-5 - 发表时间:
2012 - 期刊:
- 影响因子:0
- 作者:
P. Warde;David Hogg;M. Gospodarowicz - 通讯作者:
M. Gospodarowicz
David Hogg的其他文献
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{{ truncateString('David Hogg', 18)}}的其他基金
Collaborative Research: Community Planning for Scalable Cyberinfrastructure to Support Multi-Messenger Astrophysics
合作研究:支持多信使天体物理学的可扩展网络基础设施的社区规划
- 批准号:
1841594 - 财政年份:2018
- 资助金额:
$ 469.65万 - 项目类别:
Standard Grant
Analysing the Motion of Biological Swimmers
分析生物游泳者的运动
- 批准号:
EP/S01540X/1 - 财政年份:2018
- 资助金额:
$ 469.65万 - 项目类别:
Research Grant
New Probabilistic Methods for Observational Cosmology
观测宇宙学的新概率方法
- 批准号:
1517237 - 财政年份:2015
- 资助金额:
$ 469.65万 - 项目类别:
Standard Grant
CDI-Type I: A Unified Probabilistic Model of Astronomical Imaging
CDI-Type I:天文成像的统一概率模型
- 批准号:
1124794 - 财政年份:2011
- 资助金额:
$ 469.65万 - 项目类别:
Standard Grant
Dynamical Models from Kinematic Data: The Milky Way Disk and Halo
运动学数据的动力学模型:银河系盘和光环
- 批准号:
0908357 - 财政年份:2009
- 资助金额:
$ 469.65万 - 项目类别:
Standard Grant
Cognitive Systems Foresight: Human Attention and Machine Learning
认知系统前瞻:人类注意力和机器学习
- 批准号:
EP/E010164/1 - 财政年份:2007
- 资助金额:
$ 469.65万 - 项目类别:
Research Grant
Learning about Activities from Video
从视频中了解活动
- 批准号:
EP/D061334/1 - 财政年份:2006
- 资助金额:
$ 469.65万 - 项目类别:
Research Grant
ITR - ASE - int+dmc+soc: Automated Astrometry for Time-Domain and Distributed Astrophysics
ITR - ASE - int dmc soc:时域和分布式天体物理学的自动天体测量
- 批准号:
0428465 - 财政年份:2004
- 资助金额:
$ 469.65万 - 项目类别:
Standard Grant
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