DNA CYTOMETRY CONSENSUS CONFERENCE

DNA 细胞计数共识会议

• 批准号: 3434253
• 负责人: LEON L WHEELESS
• 金额: $ 1.15万
• 依托单位: UNIVERSITY OF ROCHESTER
• 依托单位国家: 美国
• 财政年份: 1992
• 资助国家: 美国
• 起止时间: 1992-07-27 至 1993-07-26
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3434253
• 关键词: DNA; aneuploidy; flow cytometry; meeting /conference /symposium; neoplasm /cancer; prognosis

The DNA Cytometry Consensus Conference will discuss and critically evaluate the current state of knowledge and usefulness of measurements of DNA content in the management of individual patients for the following organ sites: Breast, Colon and Rectum, Bladder, and Prostate. For each of these sites, the technique has been suggested to have clinical utility. Core groups of internationally recognized experts will review the published studies and pertinent recent unpublished results for each organ site. Results from comparable studies will be evaluated whenever possible using quantitative analysis. In other cases a qualitative expert consensus will be attempted. If no consensus can be reached, the critical studies necessary to validate the technique will be defined. one session will be devoted to defining the necessary uniformly recognized standards for specimen preparation, flow or image cytometry technique, data analysis and interpretation of results. The primary objectives of the conference are to: 1) Provide a forum in which key international experts can examine in detail the clinical utility of DNA cytometry in solid tumors of the breast, colon and rectum, bladder, and prostate. 2) Reach a consensus on the clinical utility of DNA cytometry for the above organ sites. 3) Identify areas in which results are insufficient to reach a consensus and define the critical experiments required to reach a consensus. 4) Establish guidelines for specimen collection and preparation, standardization, data analysis, and interpretation, which are necessary to evaluate and to assure comparability of studies. 5) Publish the resulting consensus statements in appropriate journals to provide guidelines for the use of DNA cytometry in routine clinical practice.

DNA细胞仪共识会议将讨论并进行批判性讨论 评估当前的知识状态和测量的实用性 以下各个患者管理中的DNA含量 器官部位：乳房，结肠和直肠，膀胱和前列腺。 每个 在这些站点中，已建议该技术具有临床 公用事业。 国际知名专家的核心群体将审查 已发表的研究和相关的最新未发表的结果 风琴站点。 每当可比较研究的结果时 可能使用定量分析。在其他情况下，定性专家 将尝试共识。如果无法达成共识，那么关键 验证技术所需的研究将被定义。一个会话 将致力于定义必要的统一标准 用于标本准备，流量或图像细胞仪技术，数据 结果分析和解释。 的主要目标 会议将： 1）提供一个论坛，关键国际专家可以在其中检查 详细说明DNA细胞仪在实体瘤中的临床实用性 乳房，结肠和直肠，膀胱和前列腺。 2）就DNA细胞术的临床实用性达成共识 在器官位置上方。 3）确定结果不足以达成共识的领域 并定义达成共识所需的关键实验。 4）建立标本收集和准备的准则， 标准化，数据分析和解释是必要的 评估并确保研究的可比性。 5）在适当的期刊上发布结果的共识声明 提供在常规临床中使用DNA细胞仪的指南 实践。