CONNECTIONS OF FRONTAL AGRANULAR CORTEX

额叶无颗粒皮层的连接

• 批准号: 3398568
• 负责人: SHARLEEN T SAKAI
• 金额: $ 6.12万
• 依托单位: MICHIGAN STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1982
• 资助国家: 美国
• 起止时间: 1982-07-01 至 1990-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3398568
• 关键词: frontal lobe /cortex; neuroanatomy

Results from a number of studies have suggested that the frontal agranular cortex plays a unique role in the complex sequencing of movements in primates. Furthermore, it is thought that area 6 is involved in the prehensile use of limbs. The overall objective of this proposal it to determine the anatomical and functional relationships of area 6 subdivisions in two behaviorally distinct carnivores, the dog and raccoon. The raccoon is noted for the manipulative capabilities of its forepaws while the dog uses its distal limbs primarily in locomotion. Both autoradiography and horseradish peroxidase techniques will be employed to determine the efferent and efferent connectivity of area 6. Additionally, the double fluorescent tracing technique and the autoradiographic tritiated wheat germ agglutinin technique in combination with horseradish peroxidase technique wil be used to determine the extent of collateralized thalamocortical projections of area 6.

许多研究的结果表明，额叶额观 皮层在运动中的复杂测序中起着独特的作用 灵长类动物。 此外，人们认为区域6参与 肢体使用前使用。 该提议的总体目标 确定区域6的解剖和功能关系6 在两个行为不同的食肉动物中，狗和浣熊的细分。 浣熊以其前爪的操纵能力而闻名 狗主要在运动中使用其远端四肢。 两个都 放射自显影和辣根过氧化物酶技术将采用 确定区域6的传出和传出连接性。此外， 双荧光追踪技术和放射自显影 小麦胚芽凝集素技术与辣根过氧化物酶结合 技术将用于确定抵押的程度 区域6。

项目成果

Thalamic afferents of area 4 and 6 in the dog: a multiple retrograde fluorescent dye study.

狗 4 区和 6 区丘脑传入神经：多重逆行荧光染料研究。

• DOI: 10.1007/bf00187010
• 发表时间: 1993
• 期刊: Anatomy and embryology
• 作者: Sakai,ST;Stanton,GB;Isaacson,LG
• 通讯作者: Isaacson,LG

Corticonigral projections from area 6 in the raccoon.

浣熊 6 区的皮质黑质投射。

• DOI: 10.1007/bf00406607
• 发表时间: 1988
• 期刊: Experimental brain research
• 影响因子: 2
• 作者: Sakai,ST

Corticospinal projections from areas 4 and 6 in the raccoon.

浣熊 4 区和 6 区的皮质脊髓投射。

• DOI: 10.1007/bf00608232
• 发表时间: 1990
• 期刊: Experimental brain research
• 影响因子: 2
• 作者: Sakai,ST

Distribution of nigrothalamic projections in the dog.

狗黑丘脑投射的分布。

• DOI: 10.1002/cne.903180106
• 发表时间: 1992
• 期刊: The Journal of comparative neurology
• 作者: Sakai,ST;Smith,A
• 通讯作者: Smith,A