REMOVAL/INACTIVATION OF VIRUSES IN BLOOD

血液中病毒的去除/灭活

• 批准号: 3359110
• 负责人: GIRISH N VYAS
• 金额: $ 39.14万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 1988
• 资助国家: 美国
• 起止时间: 1988-07-01 至 1991-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3359110
• 关键词: Betaherpesvirinae; adsorption; antiAIDS agent; antiviral agents; antiviral antibody; blood banks; blood filtration; hepatitis B virus group; hepatitis C virus; human immunodeficiency virus 1; human tissue; immune adherence reaction; leukapheresis; monoclonal antibody; natural gene amplification; nucleic acid hybridization; nucleic acid probes; retinoate; synthetic peptide; virus DNA

National focus on the AIDS epidemic has-stimulated an urgent need to prevent our blood resources transmitting a multiplicity of blood-borne viruses (BBVs), including the human immunodeficiency virus (HIV), non-A, non-B hepatitis virus (NANBHVs), hepatitis B virus (HBV), cytomegalovirus (CMV), human T-cell leukemia virus (HTLV-I/II, variants of HIV, and several other viral agents whose importance has not been fully recognized. Assessment of adsorption for virus or chemical inactivation in the experimentally infected units of blood components and plasma products is envisaged by using HIV as a prototype in vitro cultures and viral gene detection by polymerase chain reaction (PCR).

国家对艾滋病流行的关注已刺激了迫切需求 为了防止我们的血液资源传播多样性 血源性病毒（BBV），包括人类免疫缺陷 病毒（HIV），非A，非B肝炎病毒（NANBHV），乙型肝炎 病毒（HBV），巨细胞病毒（CMV），人类T细胞白血病病毒 （HTLV-I/II，HIV的变体和其他几种病毒剂 重要性尚未得到充分认可。 评估病毒或化学失活的吸附 实验感染的血液成分和等离子体单位 通过将HIV用作体外培养物的原型来设想产品 通过聚合酶链反应（PCR）检测病毒基因。