Vector-borne RADAR (Real-time Arbovirus Detection And Response)

媒介传播雷达（实时虫媒病毒检测和响应）

基本信息

批准号：
BB/X017990/1
负责人：
Arran Folly
金额：
$ 117.73万
依托单位：
ANIMAL AND PLANT HEALTH AGENCY
依托单位国家：
英国
项目类别：
Research Grant
财政年份：
2023
资助国家：
英国
起止时间：
2023 至无数据
项目状态：
未结题

来源：
https://gtr.ukri.org/projects?ref=BB%2FX017990%2F1
关键词：
Vector borne RADAR Real time

项目摘要

Vector-borne RADAR looks to enhance surveillance of mosquito-borne diseases of wild birds in the UK that have wider medical and veterinary importance by adopting a One Health approach. Our first work package will increase the scope of our successful, multi-disciplinary network, which was responsible for the detection of Usutu virus in the UK in 2020, to include additional routes for sampling both bird hosts and mosquito vectors. This will follow a similar and successful paradigm that has been used in the Netherlands to detect emerging mosquito borne viruses of wild birds (www.onehealthpact.org). In essence we will co-opt bird observatories and licensed ringers in areas deemed at high-risk of virus incursion to sample migrant birds (to identify potential routes of virus incursion) and resident birds (to elucidate geographic extent and virus prevalence). At each of our designated bird sampling sites we will also set up mosquito traps to provide information on vector community composition, virus prevalence and potential transmission networks. Our second work package will develop an early warning system for the detection of potential zoonotic viral diseases of wild birds in the UK. Two existing and independent citizen science data schemes (the British Trust for Ornithology's [BTO] Garden BirdWatch, and the Garden Wildlife Health [GWH] project) will be co-opted to identify clusters of disease incident reports which correlate with a reduction in wild bird reporting rates, as a proxy to indicate areas of virus circulation and assess near real-time impact. This approach has been shown to be successful, by our consortium, in retrospectively identifying patterns of Blackbird mortality and declines in reporting rates caused by the 2020 Usutu virus outbreak in the UK. Our third work package will be conducted in collaboration with citizen scientists who participate in the BTO Garden BirdWatch. We will undertake a survey aiming to understand fine-scale Blackbird movements and habitat use in UK gardens. Data generated will provide detail on specific habitat use and identify potential virus transmission risks in relation to habitat features of gardens that are also likely to encourage higher mosquito populations (e.g. areas of stagnant water). Alongside this we will establish Blackbird trapping sites in London and the south-east, where licensed ringers will aim to catch birds in mist nets and colour-ring (so they can be identified from a distance without the need for further trapping) individual Blackbirds in order to quantify survival rates through time. Ringers involved in the scheme will also be trained to deploy mosquito traps and identify mosquitoes to provide evidence to link vector abundance and disease prevalence directly to wild bird survival.The data generated from this research proposal will improve our understanding of how exotic mosquito-borne viruses emerge and persist in temperate areas while also feeding directly into government policy & risk assessments on zoonotic diseases, public health messages and mosquito control strategies. Through engagement with citizen scientists, wildlife rehabilitators, zoological collections, and animal welfare and conservation NGOs, we will also raise awareness of implications for animal health and impacts on biodiversity.

病媒传播雷达旨在通过采用“同一个健康”方法，加强对英国野生鸟类蚊媒疾病的监测，这些疾病具有更广泛的医疗和兽医重要性。我们的第一个工作包将扩大我们成功的多学科网络的范围，该网络负责 2020 年在英国检测乌苏图病毒，其中包括对鸟类宿主和蚊媒进行采样的其他路线。这将遵循荷兰已使用的类似且成功的范例，用于检测新出现的蚊媒野生鸟类病毒（www.onehealthpact.org）。本质上，我们将在被认为存在病毒入侵高风险的地区选择鸟类观测站和获得许可的鸟类样本，以对候鸟（以确定病毒入侵的潜在途径）和留鸟（以阐明地理范围和病毒流行情况）进行采样。在我们指定的每个鸟类采样点，我们还将设置捕蚊器，以提供有关病媒群落组成、病毒流行率和潜在传播网络的信息。我们的第二个工作包将开发一个早期预警系统，用于检测英国野生鸟类潜在的人畜共患病毒性疾病。两个现有的独立公民科学数据计划（英国鸟类学信托基金的 [BTO] 花园观鸟项目和花园野生动物健康 [GWH] 项目）将被选为确定与野生鸟类减少相关的疾病事件报告集群报告率，作为指示病毒传播区域并评估近实时影响的代理。我们的联盟在回顾性确定 2020 年英国乌苏图病毒爆发导致的黑鸟死亡率和报告率下降方面已证明这种方法是成功的。我们的第三个工作包将与参与 BTO 花园观鸟活动的公民科学家合作进行。我们将进行一项调查，旨在了解英国花园中黑鸟的精细活动和栖息地利用情况。生成的数据将提供有关特定栖息地使用的详细信息，并确定与花园栖息地特征相关的潜在病毒传播风险，这些特征也可能鼓励更多的蚊子种群（例如积水区域）。除此之外，我们还将在伦敦和东南部建立黑鸟诱捕点，在那里，获得许可的捕鸟者将致力于用雾网和色环捕捉鸟类（这样就可以从远处识别它们，而不需要进一步诱捕）个体黑鸟。为了量化随时间变化的存活率。参与该计划的林格还将接受培训，以部署蚊子捕捉器并识别蚊子，从而提供证据，将病媒丰度和疾病流行率与野鸟生存直接联系起来。这项研究提案产生的数据将提高我们对外来蚊媒病毒如何传播的理解。在温带地区出现并持续存在，同时也直接影响政府关于人畜共患疾病的政策和风险评估、公共卫生信息和蚊子控制策略。通过与公民科学家、野生动物康复者、动物收藏以及动物福利和保护非政府组织的合作，我们还将提高人们对动物健康影响和生物多样性影响的认识。