RNA Polymerase III in healthy ageing: Consolidating the mechanisms of longevity from worms and flies to mice

RNA聚合酶III在健康衰老中的作用：巩固从蠕虫和苍蝇到小鼠​​的长寿机制

• 批准号: BB/S014365/1
• 负责人: Jennifer Tullet
• 金额: $ 50.49万
• 依托单位: University of Kent
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2019
• 资助国家: 英国
• 起止时间: 2019 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FS014365%2F1
• 关键词: RNA; Polymerase; III; healthy; ageing

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

GTR目前尚未用于所有资助研究的摘要。这通常是因为提交提案时不需要摘要，但可能是因为它包含了敏感信息，例如个人详细信息。

项目成果

RNA Polymerase III, Ageing and Longevity.

• DOI: 10.3389/fgene.2021.705122
• 发表时间: 2021
• 期刊: Frontiers in genetics
• 影响因子: 3.7
• 作者: Kulaberoglu Y;Malik Y;Borland G;Selman C;Alic N;Tullet JMA
• 通讯作者: Tullet JMA

Polr3b heterozygosity in mice induces both beneficial and deleterious effects on health during ageing with no effect on lifespan

• DOI: 10.1111/acel.14141
• 发表时间: 2024-03-11
• 期刊: AGING CELL
• 影响因子: 7.8
• 作者: Borland，Gillian;Wilkie，Stephen E.;Selman，Colin
• 通讯作者: Selman，Colin

Mendelian randomization analyses implicate biogenesis of translation machinery in human aging.

• DOI: 10.1101/gr.275636.121
• 发表时间: 2022-03
• 期刊: Genome research
• 影响因子: 7
• 作者: Javidnia S;Cranwell S;Mueller SH;Selman C;Tullet JMA;Kuchenbaecker K;Alic N
• 通讯作者: Alic N