Unlocking the Brown Macroalgal Cell Wall: From Renewable UK Resource to Value-Added Chemicals and Pharmaceuticals

解锁棕色巨藻细胞壁：从英国可再生资源到增值化学品和药品

基本信息

批准号：
BB/S010610/1
负责人：
Emily Kostas
金额：
$ 38.19万
依托单位：
University College London
依托单位国家：
英国
项目类别：
Fellowship
财政年份：
2019
资助国家：
英国
起止时间：
2019 至无数据
项目状态：
已结题

来源：
https://gtr.ukri.org/projects?ref=BB%2FS010610%2F1
关键词：
Unlocking Brown Macroalgal Cell Wall

项目摘要

The need to identify suitable feedstocks that are capable of being used in biorefinery processes to recover a range of valuable products is of increasing significance. This will help to ensure that mankind makes efficient usage of bioresources and to replace petro-chemical derived sources. Seaweeds are an attractive bioresource compared to land-based plants because they are an underutilised resource, do not require terrestrial land for growth and cultivation and do not directly compete with food sources. More than 644 different types of seaweed inhabit UK waters, offering great potential for the UK seaweed bio-economy to expand. Despite this, harvested quantities are currently too low (circa >3000 dry tonnes pa) to expand the UK's seaweed industry which was last valued at £1.3 m in 2012. This is because of distribution and accessibility issues and policy limitations that are associated with harvesting regulations and licensing. Nonetheless, seaweeds have the possibility to propel the UK bio-economy since they possesses a wealth of valuable compounds for applications in pharmaceuticals, food and cosmetics, or conversion into biofuels. This research that will be held at University College London, aims to underpin how to efficiently access these compounds and sustainably recover them from the UK abundant brown seaweed Laminaria digitata. The target compounds of interest (polysaccharides) are locked up in the seaweed cell wall, but there is little information in the current literature about their location and structural arrangements. Therefore, this project will firstly see to investigate L. digitata's cell wall biological architecture and locate the whereabouts of the targeted polysaccharides of interest. By elucidating their location/architectural arrangement in this research, compatible and sustainable extraction methods will be developed with the aim to maximum extraction yields. In addition, novel applications for these extracted polysaccharides across different UK industrial sectors will be identified including food and beverage, pharmaceutical and biofuel. This research will ultimately drive the development of novel UK-seaweed bio-refineries and add value to the UK-bioeconomy, something that is particularly critical in the current post-Brexit landscape.

寻找能够用于生物精炼过程以回收一系列有价值产品的合适原料的需求日益重要，这将有助于确保人类有效利用生物资源并取代石化来源。与陆生植物相比，海藻是一种有吸引力的生物资源，因为它们是一种未充分利用的资源，不需要陆地来生长和栽培，并且不与食物来源直接竞争超过 644 种不同类型的海藻。栖息在英国水域，为英国海藻生物经济的发展提供了巨大的潜力，尽管如此，目前的捕捞量还太低（每年约>3000干吨），无法扩大英国海藻产业的规模，该产业的最新价值是在2012年130万英镑。这是因为与收获法规和许可相关的分配和可及性问题以及政策限制。然而，海藻有可能推动英国的生物经济，因为它们拥有丰富的宝贵资源。这项研究将在伦敦大学学院进行，旨在支持如何有效地获取这些化合物并从英国丰富的褐海藻中可持续地回收它们。感兴趣的化合物（多糖）被锁定在海藻细胞壁中，但目前的文献中关于它们的位置和结构排列的信息很少，因此，该项目将首先研究海藻的细胞。通过在本研究中阐明其位置/结构排列，将开发兼容且可持续的提取方法，以最大限度地提高提取率。此外，这些提取的多糖的新应用。这项研究将最终推动英国海藻生物精炼厂的发展，并为英国生物经济增加价值。这在当前脱欧后的形势下尤为重要。

项目成果

期刊论文数量（10）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

A comprehensive comparative study on methylene blue removal from aqueous solution using biochars produced from rapeseed, whitewood, and seaweed via different thermal conversion technologies

DOI：
10.1016/j.fuel.2022.125428
发表时间：
2022-08-10
期刊：
FUEL
影响因子：
7.4
作者：
Guelec, Fatih;Williams, Orla;Lester, Edward
通讯作者：
Lester, Edward

Exploring the Utilisation of Natural Biosorbents for Effective Methylene Blue Removal

DOI：
10.3390/app14010081
发表时间：
2023-12
期刊：
Applied Sciences
影响因子：
0
作者：
Fatih Güleç;O. Williams;Abby Samson;E. Kostas;Lee A. Stevens;Edward Lester
通讯作者：
Fatih Güleç;O. Williams;Abby Samson;E. Kostas;Lee A. Stevens;Edward Lester

Macroalgal biorefinery concepts for the circular bioeconomy: A review on biotechnological developments and future perspectives