PANACEA: Pathogenomics for enhancing food security in East Africa

PAACEA：加强东非粮食安全的病理基因组学

• 批准号: BB/R015376/1
• 负责人: Thomas Wood
• 金额: $ 14.9万
• 依托单位: National Institute of Agricultural Botany
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2018
• 资助国家: 英国
• 起止时间: 2018 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FR015376%2F1
• 关键词: PANACEA; Pathogenomics; enhancing; food; security

SummaryCommon bean is an essential source of nutrients, vitamins and minerals to approximately 300 million consumers worldwide. Pest and disease, such as angular leaf spot (ALS) caused by Pseudocercospora griseola, can seriously reduce yields and quality, leading to malnutrition and lost incomes. Farmers often rely on growing resistant varieties to combat the effects of disease but unfortunately ALS is genetically diverse, so selecting the best-performing varieties can be problematic. Providing resources for pathotyping fungal pathogens like ALS can help researchers and plant breeders to improve disease management, variety selection and guide the development of new, resistant varieties to help growers to stabilise productivity and to reduce the incidence and severity of disease outbreaks. The pump-priming project will help to establish new, innovative biological and bioinformatics resources that will provide local experts and researchers with enhanced capability to accurately monitor for differences in ALS races. This will enable new or novel pathotypes to be identified when arise, and if they pose a potential threat to a growing region, allowing for interventions to be made in good time. The resources will comprise of:i) An initial pathogen collection of 75-100 P. griseola isolates sampled from across the nine different Ugandan agro-ecologiesii) Genomic resources developed around the panel providing genotyping information for pathotyping and functional studiesiii) A population diversity screen using the new genomic resource to begin to shed light on ALS pathotypes affecting East African bean cropsiv) Series of meetings, webinars and workshops to optimise the new resources for end-user utility and demonstrate the new resource to stakeholders and local experts.The new resources will begin to facilitate improved monitoring and surveillance of P. griseola the causal agent of ALS on common bean in order to help prevent future disease outbreaks and to guide variety selection and the breeding of new varieties. This will contribute directly to stabilise yields and productivity, enhancing nutritional intakes and incomes for small-holder farmers and the millions of consumers dependent on common bean as a cheap, nutritious source of food. The resources will also have wider application to scientific researchers with interests in more fundamental aspects of pathogen genomics and epidemiology. The initial framework developed during the project could be applied to other crops/pathogens to support further improvement efforts.

摘要豆是全球约3亿消费者的营养素，维生素和矿物质的重要来源。害虫和疾病，例如由伪cospora griseola引起的角叶点（ALS），可以严重降低产量和质量，从而导致营养不良和收入损失。农民通常依靠增长的抗性品种来打击疾病的影响，但不幸的是，ALS在遗传上是多种多样的，因此选择表现最佳的品种可能是有问题的。提供用于病原体病原体（如ALS）的资源可以帮助研究人员和植物育种者改善疾病管理，品种选择，并指导新的耐药品种的发展，以帮助种植者稳定生产力并降低疾病暴发的发生率和严重性。该泵送项目将有助于建立新的，创新的生物学和生物信息学资源，这些资源将为当地专家和研究人员提供增强的能力，以准确监视ALS种族的差异。这将使出现时可以识别出新的或新颖的病原体，如果它们对不断增长的地区构成潜在威胁，从而可以在及时进行干预措施。 The resources will comprise of:i) An initial pathogen collection of 75-100 P. griseola isolates sampled from across the nine different Ugandan agro-ecologiesii) Genomic resources developed around the panel providing genotyping information for pathotyping and functional studiesiii) A population diversity screen using the new genomic resource to begin to shed light on ALS pathotypes affecting East African bean cropsiv) Series of meetings,网络研讨会和研讨会，以优化最终用户实用程序的新资源，并向利益相关者和本地专家展示新资源。新资源将开始促进对P. Griseola P. Griseola的监测和监视，为ALS上的ALS bean的因果毒剂，以帮助防止未来的疾病暴发，并为新品种提供新品种的繁殖。这将直接有助于稳定产量和生产力，增强小型农民的营养摄入量和收入，数百万的消费者依赖普通豆作为廉价，营养丰富的食物来源。资源还将在病原体基因组学和流行病学的更基本方面具有兴趣的科学研究人员提供更广泛的应用。在项目期间开发的最初框架可以应用于其他农作物/病原体，以支持进一步的改进工作。