The evolutionary emergence of multidrug resistant bacterial pathogens

多重耐药细菌病原体的进化出现

• 批准号: BB/R006253/1
• 负责人: Michael Brockhurst
• 金额: $ 45.41万
• 依托单位: University of Sheffield
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2018
• 资助国家: 英国
• 起止时间: 2018 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FR006253%2F1
• 关键词: evolutionary; emergence; multidrug; resistant; bacterial

Abstracts are not currently available in GtR for all funded research. This is normally because the abstract was not required at the time of proposal submission, but may be because it included sensitive information such as personal details.

GTR目前尚未用于所有资助研究的摘要。这通常是因为提交提案时不需要摘要，但可能是因为它包含了敏感信息，例如个人详细信息。

项目成果

Limited and strain-specific transcriptional and growth responses to acquisition of a multidrug resistance plasmid in genetically diverse Escherichia coli lineages

在遗传多样性的大肠杆菌谱系中获得多药耐药质粒的有限且菌株特异性的转录和生长反应

• DOI: 10.1101/2020.10.23.351718
• 发表时间: 2020
• 作者: Dunn S

Evolutionary Responses to Acquiring a Multidrug Resistance Plasmid Are Dominated by Metabolic Functions across Diverse Escherichia coli Lineages.

• DOI: 10.1128/msystems.00713-22
• 发表时间: 2023-02-23
• 期刊: mSystems
• 影响因子: 6.4

Limited and Strain-Specific Transcriptional and Growth Responses to Acquisition of a Multidrug Resistance Plasmid in Genetically Diverse Escherichia coli Lineages.

• DOI: 10.1128/msystems.00083-21
• 发表时间: 2021-04-27
• 期刊: mSystems
• 影响因子: 6.4
• 作者: Dunn S;Carrilero L;Brockhurst M;McNally A
• 通讯作者: McNally A

The dilution effect limits plasmid horizontal transmission in multispecies bacterial communities.

• DOI: 10.1099/mic.0.001086
• 发表时间: 2021-09
• 期刊: Microbiology (Reading, England)
• 作者: Kottara A;Carrilero L;Harrison E;Hall JPJ;Brockhurst MA
• 通讯作者: Brockhurst MA

Evolutionary responses to acquiring a multidrug resistance plasmid are dominated by metabolic functions across diverse Escherichia coli lineages

获得多药耐药质粒的进化反应由不同大肠杆菌谱系的代谢功能主导

• DOI: 10.1101/2022.07.22.501110
• 发表时间: 2022
• 作者: Carrilero L