BBSRC Embrapa: Using computational novel methods to characterise the genetics of tan spot resistance in wheat.

BBSRC Embrapa：使用计算新方法来表征小麦褐斑病抗性的遗传学。

• 批准号: BB/N004469/1
• 负责人: Narcis Fernandez-Fuentes
• 金额: $ 5.94万
• 依托单位: Aberystwyth University
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2015
• 资助国家: 英国
• 起止时间: 2015 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FN004469%2F1
• 关键词: BBSRC; Embrapa; Using; computational; novel

Dr Anyela Camargo, will add her expertise in computer vision, systems biology, statistics and bionformatics to the project. She has been interested in the topic of plant disease monitoring since his time at Corpoica where she developed a tool for monitoring cotton crops. At Liverpool University she developed a system for the early detection of plant disorders. Later she was involved in the modelling of the gene network describing stress responses in Arabidopsis. Now, she is using the Brachypodium distachon plant model to identify genes associated to the resistance to blast rice.Prof. John Doonan is the director of the National Plant Phenomics Centre, he will add his expertise in genetics and molecular biology to help characterise, from the molecular point of view, the resistance to wheat to tan spot project.Dr Narcis Fernandez-Fuentes has over 10 years of experience in different aspects of Bioinformatics and has developed a number of databases and web-servers widely used by the scientific community. Dr Fernandez-Fuentes is currently leading the Bioinformatics research within IBERS' C3G ISPG grant program, part of which relates to the discovery of genes linked to a range of traits of interest by combining a range of 'omics datasets and developing integrative approaches.Professor John Draper has worked extensively at the interface between plant biology, analytical spectroscopy and computer science. Internationally he has been a pioneer in the use of metabolomics and machine learning to investigate the early stages of pathogen invasion in non-symptomatic host tissue. He has a long publication record in metabolomics, Brachypodium biology and plant defence. IBERS, at Aberystwyth University, is a major centre for public sector plant breeding for ryegrasses, forage and oats. IBERS has an in-house high performance computer (HPC) facility, Next Generation Sequencing labs and the UK's unique National Plant Phenomics Centre. The NPPC is based around automated non-destructive image analysis system running in a purpose-built glasshouse complex. The system is designed to cope with a range of plants, including small and large plants such as oats, wheat, barley, maize and Miscanthus. The NPPC provides a focus for trans-disciplinary research to facilitate the discovery of the genetic and environmental basis for variation in complex traits that underpin the major global. Also within IBERS, the Genome Diversity and Plant Breeding group addresses the major challenge of the sustainable intensification of agriculture: enhancing production whilst reducing environmental impacts, particularly with respect to grassland dominated systems.Dr Flávio Santana is a plant pathologist at Embrapa Trigo since 2006. Since then he is working in characterization of tan spot disease isolates from Brazil. He also is responsible as coordinator of a fungicide control of Wheat Blast and Fusarium Head Blight in several States in Brazil. In this Project he will be committed with the phenotyping of a population of resistant and susceptible wheat cultivars to tan spot disease.Dr Ricardo Lima de Castro has experience in agronomy with emphasis on plant breeding, working mainly in wheat breeding, biometrics and quantitative genetics. In Embrapa Wheat he has been working in wheat breeding. Dr. Lima will identify wheat cultivars resistant and susceptible to the fungus attack deliverable (preparation of a list of cultivars and their genetic background), carry out of the trials to test resistance and help in phenotyping of resistance.Embrapa Wheat is a branch of the Nacional Agricultural Research Center (Embrapa) where several researchers are directly involved in all area of agricultural science related to wheat, as plant pathology, entomology, weed control, plant physiology, soil nutrition, of which the main focus is wheat breeding. The facilities are well equipped with greenhouses, fields for trials and research labs.

Anyela Camargo 博士将在该项目中加入她在计算机视觉、系统生物学、统计学和生物信息学方面的专业知识，自从在 Corpoica 工作以来，她一直对植物病害监测主题感兴趣，在那里她开发了一种用于监测棉花作物的工具。在大学期间，她开发了一种早期检测植物疾病的系统，后来她参与了描述拟南芥应激反应的基因网络建模，现在，她正在使用短柄草植物模型来识别与抗性相关的基因。 John Doonan 教授是国家植物表型组学中心的主任，他将利用他在遗传学和分子生物学方面的专业知识，从分子角度帮助表征小麦对棕褐色斑点的抗性。 -Fuentes 在生物信息学的不同方面拥有超过 10 年的经验，并开发了许多被科学界广泛使用的数据库和网络服务器，目前正在领导该项目。 IBERS 的 C3G ISPG 资助计划中的生物信息学研究，其中一部分涉及通过结合一系列“组学”数据集和开发综合方法来发现与一系列感兴趣的性状相关的基因。John Draper 教授在在国际上，他是利用代谢组学和机器学习研究病原体侵入无症状宿主组织的早期阶段的先驱。阿伯里斯特威斯大学 IBERS 在代谢组学、短柄草生物学和植物防御方面拥有长期发表记录，是黑麦草、饲料和燕麦公共部门植物育种的主要中心，拥有内部高性能计算机 (HPC) 设施“下一代”。 NPPC 的测序实验室和英国独特的国家植物表型组学中心基于在专门建造的温室综合体中运行的自动化无损图像分析系统。系统旨在应对一系列植物，包括燕麦、小麦、大麦、玉米和芒草等小型和大型植物。NPPC 为跨学科研究提供了焦点，以促进发现变异的遗传和环境基础。同样在 IBERS 内部，基因组多样性和植物育种小组解决了农业可持续集约化的主要挑战：提高产量，同时减少环境影响，特别是在草原主导系统方面。 Flávio Santana 自 2006 年起担任 Embrapa Trigo 的植物病理学家。此后，他致力于巴西棕斑病分离株的鉴定。他还担任巴西多个州小麦瘟疫和赤霉病杀菌剂控制的协调员。在这个小麦项目中，他将致力于对棕斑病具有抗性和易感性的品种群体进行表型分析。Ricardo Lima de Castro 博士拥有农学经验，重点关注植物育种，主要从事小麦育种、生物识别和定量遗传学工作。利马博士在 Embrapa Wheat 从事小麦育种工作，将鉴定抗真菌且易受真菌侵袭的小麦品种（准备品种清单及其遗传信息）。 Embrapa 小麦是国家农业研究中心 (Embrapa) 的一个分支机构，该中心的几位研究人员直接参与了所有研究与小麦相关的农业科学领域，如植物病理学、昆虫学、杂草控制、植物生理学、土壤营养学，其中主要重点是小麦育种，设施齐全，有温室、试验田和研究实验室。

项目成果

Determining Phenological Patterns Associated with the Onset of Senescence in a Wheat MAGIC Mapping Population.

• DOI: 10.3389/fpls.2016.01540
• 发表时间: 2016
• 期刊: Frontiers in plant science
• 影响因子: 5.6
• 作者: Camargo AV;Mott R;Gardner KA;Mackay IJ;Corke F;Doonan JH;Kim JT;Bentley AR
• 通讯作者: Bentley AR