COURSE AND OUTCOME OF NEURASTHENIA IN CHINA

中国神经衰弱的病程和结局

• 批准号: 2797166
• 负责人: YAN-PING ZHENG
• 金额: $ 1.69万
• 依托单位: LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-09-30 至 2001-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2797166
• 关键词: China; Chinese; Chinese American; behavior prediction; clinical research; culture; data collection; depression; ethnic group; fatigue; human subject; international cooperation; longitudinal human study; mental disorder diagnosis; nervous system disorder; outcomes research; prognosis; racial /ethnic difference; social psychology

DESCRIPTION This application seeks funding to conduct a long-term longitudinal study of the course and outcome of a group of ICD-10 defined neurasthenia (NT) patients previously enrolled in a multi-site cross-sectional study involving an extensive clinical/ethnographic protocol. All subjects have been previously evaluated with the use of the SCID, HCL-90, HAMD, HADA, and a semi-structured ethnographic interview instrument (EMIC) for the collection of both qualitative and quantitative data. Similar to the parent grant, this study will examine the following issues in a Chinese patient population: (1) temporal stability of the NT diagnosis; (2) biopsychosocial predictors of the outcome and prognosis; and (3) cultural expressions of the illness during its course. This application will extend the parent study by adding an international, cross-site component that will not only significantly increase the sample size, but also allow the investigators to examine and compare the unity as well as diversity of Chinese cultures at the two sites, and how they differentially shape illness experiences and outcome. In addition to these research goals, the project also will further facilitate and maintain the collaboration in research and training between the two collaborative institutions, and foster further development of research programs in this and other related areas.

描述 该申请寻求资金来进行长期纵向研究 ICD-10 定义的神经衰弱 (NT) 组的病程和结果 患者之前参加了一项多中心横断面研究，涉及 广泛的临床/人种学协议。 所有科目均已 之前使用 SCID、HCL-90、HAMD、HADA 和 针对馆藏的半结构化人种学访谈工具 (EMIC) 定性和定量数据。 与家长补助类似， 本研究将检查中国患者的以下问题 人群：(1) NT 诊断的时间稳定性； (2) 生物心理社会 结果和预后的预测因素； (3) 文化表现形式 疾病在其病程中。 该应用程序将通过以下方式扩展家长研究 添加一个国际化的跨站点组件，不仅可以 显着增加样本量，同时也让研究人员能够 考察和比较中国文化的统一性和多样性 这两个地点，以及它们如何不同地塑造疾病经历和 结果。 除了这些研究目标外，该项目还将进一步 促进和维持研究和培训方面的合作 两个合作机构，并促进进一步发展 该领域和其他相关领域的研究计划。