Plant UV-B photoreceptor signalling

植物 UV-B 光感受器信号传导

• 批准号: BB/J008494/1
• 负责人: Gareth Islwyn Jenkins
• 金额: $ 52.14万
• 依托单位: University of Glasgow
• 依托单位国家: 英国
• 项目类别: Research Grant
• 财政年份: 2012
• 资助国家: 英国
• 起止时间: 2012 至 无数据
• 项目状态: 已结题
• 来源: https://gtr.ukri.org/projects?ref=BB%2FJ008494%2F1
• 关键词: Plant; UV; photoreceptor; signalling

Ultraviolet-B (UV-B) radiation is a minor but very energetic component of sunlight. Exposure to UV-B wavelengths (280-315 nm) has numerous effects on plants, including changes in metabolism and development. Importantly, UV-B stimulates responses in plants that protect them against the potentially damaging consequences of UV-B exposure. The effects of UV-B are due to its ability to regulate the expression of numerous plant genes, including those involved in UV-protection, biosynthesis and chloroplast function. However, little is known about how UV-B is perceived by plants and how it initiates responses. The first component involved in these processes has been identified, a protein called UVR8. UVR8 acts as a photoreceptor to detect UV-B light. UVR8 interacts with another protein, COP1, to initiate responses to UV-B in plants. The aim of this project is to enhance understanding of the processes through which UVR8 and COP1 function to regulate plant responses. Establishing the molecular mechanisms of plant UV-B perception will help us to understand how UV-B regulates aspects of plant growth and development and how plants survive in sunlight.

紫外线 B (UV-B) 辐射是阳光中含量较少但能量非常高的成分。暴露于 UV-B 波长（280-315 nm）对植物有多种影响，包括新陈代谢和发育的变化。重要的是，UV-B 会刺激植物的反应，保护它们免受 UV-B 暴露的潜在破坏性后果。 UV-B 的作用是由于它能够调节许多植物基因的表达，包括那些涉及紫外线防护、生物合成和叶绿体功能的基因。然而，人们对植物如何感知 UV-B 以及它如何引发反应知之甚少。参与这些过程的第一个成分已经被鉴定出来，即一种名为 UVR8 的蛋白质。 UVR8 充当感光器来检测 UV-B 光。 UVR8 与另一种蛋白质 COP1 相互作用，启动植物对 UV-B 的反应。该项目的目的是加深对 UVR8 和 COP1 调节植物反应过程的了解。建立植物 UV-B 感知的分子机制将有助于我们了解 UV-B 如何调节植物生长和发育的各个方面以及植物如何在阳光下生存。

项目成果

UV-B detected by the UVR8 photoreceptor antagonizes auxin signaling and plant shade avoidance

UVR8 光感受器检测到的 UV-B 会拮抗生长素信号传导和植物避荫

• DOI: 10.1073/pnas.1403052111
• 发表时间: 2014-07-28
• 期刊: Proceedings of the National Academy of Sciences
• 作者: S. Hayes;Christos N. Velanis;G. Jenkins;K. Franklin
• 通讯作者: K. Franklin

A FRET method for investigating dimer/monomer status and conformation of the UVR8 photoreceptor.

用于研究 UVR8 光感受器二聚体/单体状态和构象的 FRET 方法。

• DOI: http://dx.10.1039/c8pp00489g
• 发表时间: 2019
• 期刊: Official journal of the European Photochemistry Association and the European Society for Photobiology
• 作者: Liao X

Dimer/monomer status and in vivo function of salt-bridge mutants of the plant UV-B photoreceptor UVR8.

植物 UV-B 光感受器 UVR8 盐桥突变体的二聚体/单体状态和体内功能。

• DOI: http://dx.10.1111/tpj.13260
• 发表时间: 2016
• 期刊: for cell and molecular biology
• 作者: Heilmann M

The UV-B photoreceptor UVR8: from structure to physiology.

UV-B 光感受器 UVR8：从结构到生理学。

• DOI: http://dx.10.1105/tpc.113.119446
• 发表时间: 2014
• 期刊: The Plant cell
• 作者: Jenkins GI

Q&A: How do plants sense and respond to UV-B radiation?

问

• DOI: 10.1186/s12915-015-0156-y
• 发表时间: 2015-06-30
• 期刊: BMC Biology
• 影响因子: 5.4
• 作者: R. Ulm;G. Jenkins
• 通讯作者: G. Jenkins