ENHANCING HIV PREVENTION THROUGH DRINKING REDUCTION

通过减少饮酒加强艾滋病毒预防

• 批准号: 2815947
• 负责人: KURT H DERMEN
• 金额: $ 37.95万
• 依托单位: RESEARCH INSTITUTE ON ADDICTIONS
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-09-30 至 2002-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2815947
• 关键词: AIDS education /prevention; alcoholism /alcohol abuse; alcoholism /alcohol abuse therapy; behavior modification; behavioral /social science research tag; clinical research; cognitive behavior therapy; gender difference; heterosexuals; high risk behavior /lifestyle; human subject; human therapy evaluation; sex behavior; university student

APPLICANT'S ABSTRACT: College students are at heightened behavioral risk for becoming infected with the human immunodeficiency virus (HIV). Many use condoms inconsistently and have multiple sex partners. Many college students also engage in heavy drinking, which is independently associated with increased HIV risk. Adding a drinking-reduction component may improve the efficacy of HIV risk-reduction interventions among heavy drinkers. Thus, the proposed research has three primary objectives: (1) To assess the independent and joint effects of a drinking risk-reduction intervention and an HIV risk-reduction intervention on HIV risk behavior. To this end, 200 heavy-drinking heterosexual college students at behavioral risk for HIV infection will be randomly assigned to receive no intervention, or an intervention that focuses on either reducing alcohol risk behavior, reducing HIV risk behavior, or both. Each intervention will consist of two sessions with a counselor (four weeks apart), during which the participant will receive personalized feedback on behavioral risk, will participate in motivational counseling, and will receive materials on strategies and sources of support for risk reduction. Primary dependent variables (assessed 3, 6, 9, and 15 months post-intake) will be condom use and number of sexual partners. Drinking outcomes and co-occurrence of alcohol use and sexual intercourse also will be assessed. (2) To examine the impact of participant gender on overall and differential response to the above interventions. Equal numbers of men and women will be recruited. Statistical tests will examine whether findings are generalizable across gender and, if they are not, how the findings differ by gender. (3) To explore the interrelation between change in alcohol abuse patterns and HIV risk behavior. Mediational analyses will provide critical information for interpreting between group differences. Findings from this study will have direct relevance to the implementation of HIV prevention interventions among heavy or problem drinkers, and to our understanding of the relationship between drinking and HIV risk behavior.

申请人摘要：大学生的行为风险较高 感染人类免疫缺陷病毒（HIV）。 很多用 避孕套不一致并且有多个性伴侣。 很多大学 学生也酗酒，这与 艾滋病毒风险增加。 添加减少饮酒成分可能会改善 减少酗酒者艾滋病毒风险干预措施的有效性。 因此，拟议的研究有三个主要目标： (1) 评估饮酒风险降低的独立效应和联合效应 对艾滋病毒危险行为进行干预和降低艾滋病毒风险的干预措施。 为此，200名酗酒的异性恋大学生在行为 HIV 感染风险将被随机分配为不接受干预， 或专注于减少酒精风险行为的干预措施， 减少艾滋病毒危险行为，或两者兼而有之。 每次干预将包括两个 与辅导员会面（相隔四个星期），在此期间，参与者 将收到有关行为风险的个性化反馈，将参与 动机咨询，并将收到有关策略和 降低风险的支持来源。 主要因变量 （在摄入后 3、6、9 和 15 个月进行评估）将是安全套的使用情况和数量 性伴侣。 饮酒结果和酒精使用的同时发生 性交也将被评估。 (2) 考察参与者性别对总体和差异的影响 对上述干预措施的反应。 男性和女性人数将相等 被招募了。 统计测试将检查结果是否正确 可以在不同性别之间推广，如果不能，那么研究结果有何不同 性别。 (3) 探讨酗酒模式变化之间的相互关系 和艾滋病毒危险行为。 中介分析将提供关键的 用于解释组间差异的信息。 这项研究的结果将与实施 对酗酒者或有问题的饮酒者进行艾滋病毒预防干预措施，以及我们的 了解饮酒与艾滋病毒危险行为之间的关系。