THIRD INTERNATIONAL SYMPOSIUM ON HORMONAL CARCINOGENESIS

第三届国际激素致癌研讨会

• 批准号: 2679599
• 负责人: Jonathan J. Li
• 金额: $ 2.4万
• 依托单位: UNIVERSITY OF KANSAS MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-08-01 至 1999-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2679599
• 关键词: aromatase; breast neoplasms; cell cycle; cell proliferation; endometrium; estrogens; growth factor; hormone regulation /control mechanism; hormone related neoplasm /cancer; hormone therapy; human therapy evaluation; meeting /conference /symposium; molecular genetics; neoplastic process; oncogenes; ovary neoplasms; progesterone; prostate neoplasms

DESCRIPTION (Applicant's Description) The International Symposia on Hormonal Carcinogenesis have become the premier international forum for both USA and foreign researchers studying the role of hormones and other growth regulators in the initiation, promotion, and progression of hormonal cancers. Many of these neoplasms, namely, breast, prostate, ovarian, and endometrial, represent some of the most prevalent cancers Occurring in humans. These Symposia are unique in that they bring together a group of epidemiologists, basic scientists, and clinicians of widely diverse disciplines, including cell and molecular biology, endocrinology, biochemistry, reproductive toxicology, pathology, gynecology, medicine, and epidemiology. Invited speakers are engaged in the cutting edge of hormone-associated cancer research. The Third Symposium will be held in cooperation with the Fred Hutchinson Cancer Research Center and will take place in its facilities in Seattle, WA, September 6-12,1998. Major sessions include: (1) Population/molecular epidemiologic studies of breast, prostate, and ovarian cancers; (2) Molecular genetic studies of hormonal cancer sites; (3) Estrogen receptor interactions in human and animal models; (4) Estrogen/progesterone action in breast cancer; (5) Cell cycle and cell proliferation studies in breast and endometrial cancers; (6) Oncogenes and suppressor genes; (7) Aromatase: Implications for breast cancer; and (8) Organ sites: Prostate and ovary. Symposium and State-of-the-Art lectures will be presented by outstanding investigators on subjects pertinent to hormonal carcinogenesis. The clinical session will focus on the benefits and risks of hormone and estrogen replacement therapy (HRT, ERT) in women. Both basic and clinical studies will be presented in this session. Because of the comprehensive and integrated format, these Symposia have become the sole international forum for dissemination of the latest advances in the field, providing a wider exposure of information by the timely publication of the proceedings in book form.

描述（申请人的描述） 国际激素致癌研讨会已成为 美国和外国研究人员研究的首要国际论坛 激素和其他生长调节剂在起始过程中的作用， 激素癌症的促进和进展。 许多这些肿瘤， 即乳房、前列腺、卵巢和子宫内膜，代表了一些 人类最常见的癌症。 这些研讨会的独特之处在于 他们聚集了一群流行病学家、基础科学家和 广泛不同学科的临床医生，包括细胞和分子 生物学、内分泌学、生物化学、生殖毒理学、病理学、 妇科、医学和流行病学。 受邀演讲者从事 激素相关癌症研究的前沿。 第三次研讨会将与 Fred Hutchinson 合作举办 癌症研究中心将在其位于华盛顿州西雅图的设施中进行， 1998 年 9 月 6 日至 12 日。 主要分会场包括： (1) 人口/分子 乳腺癌、前列腺癌和卵巢癌的流行病学研究； (2) 激素癌症部位的分子遗传学研究； (3)雌激素受体 人类和动物模型中的相互作用； (4) 雌激素/孕激素的作用 乳腺癌; (5) 乳腺细胞周期和细胞增殖研究 子宫内膜癌； (6)癌基因和抑制基因； (7)芳香酶： 对乳腺癌的影响； (8)器官部位：前列腺和卵巢。 研讨会和最先进的讲座将由杰出的 与激素致癌相关的受试者的研究人员。 这 临床会议将重点关注激素和药物的益处和风险 女性雌激素替代疗法（HRT、ERT）。 基础和临床 本次会议将介绍研究成果。 由于全面且 综合形式，这些研讨会已成为唯一的国际论坛 传播该领域的最新进展，提供更广泛的信息 通过及时出版会议记录书籍来公开信息 形式。