TRAINING IN MOLECULAR AND CELLULAR CARDIOLOGY

分子和细胞心脏病学培训

• 批准号: 2857721
• 负责人: ALAN B WEDER
• 金额: $ 27.47万
• 依托单位: UNIVERSITY OF MICHIGAN AT ANN ARBOR
• 依托单位国家: 美国
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-09-30 至 2001-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2857721
• 关键词: TRAINING; MOLECULAR; CELLULAR; CARDIOLOGY

This application is for a new training grant in cardiovascular science at the University of Michigan. The long term objective of this program is to train postdoctoral M.D. and Ph.D. fellows for independent basic research careers in molecular and cellular cardiovascular science. This is an interdivisional and interdepartmental program incorporating the research interests and expertise of 20 faculty members in the Departments of Internal Medicine, Biological Chemistry, Human Genetics, Microbiology/Immunology, Pathology, Pharmacology, Physiology, Surgery and the Howard Hughes Medical Institute at the University of Michigan. The faculty preceptors of the program represent an outstanding group of molecular and cellular biologists whose research interests are divided into three related cardiovascular areas: 1) the regulation of gene expression in vascular cells with emphasis on understanding the molecular basis of cellular proliferation, thrombosis and inflammation, leading to vascular pathology; 2) the molecular mechanisms regulating gene expression in cardiac and skeletal muscle during normal development and in pathophysiological states; and 3) gene therapy for cardiovascular diseases. This training grant is administered through the Cardiovascular Research Center in the Department o Internal Medicine. The program is directed by Dr. Elizabeth G. Nabel, Program Director, and Dr. Seigo Izumo, Program Co-Director, both established investigators. Dr. Nabel directs the Cardiovascular Research Center, and Dr. Izumo is the Chief of the Division of Cardiology. The Training Program is supervised by an Internal Advisory Committee comprised of senior academicians and leaders at the University of Michigan. Trainees are M.D., M.D./Ph.D, or Ph.D. postdoctoral scientists. Four postdoctoral slots in the first year and a total of eight slots in years 2-5 are requested to support fellows pursuing fulltime basic research in cardiovascular science. Each trainee will commit to 2-3 years to research training. Ph.D. postdoctoral trainees will have longterm career interests in basic cardiovascular sciences. M.D. and M.D./Ph.D. trainees will have completed three years of residency training in Internal Medicine, as well as two years of clinical cardiology subspecialty training which is fully funded by the University of Michigan Hospital. M.D. trainees participate in a Postgraduate Research Training Program Course, an established three month introductory laboratory training course in molecular and cellular biology offered by the University of Michigan Medical School. The training program is strongly committed to increasing the number of women and underrepresented minority individuals who receive training in cardiovascular research. Facilities for research training include the Cardiovascular Research Center and the individual research laboratories of the 20 preceptors located at the University of Michigan Medical Center in MSRB III/MSRB II/MSRB I/MS I and II, encompassing 29,847 sq. ft. of research space in 5 contiguous buildings. Upon completion of the training program, trainees are guided to apply for independent research funding and to pursue careers as independent investigators in cardiovascular sciences at academic medical schools.

此应用程序是为心血管中的新培训补助金 密歇根大学科学。长期目标的 该计划将培训博士后医学博士和博士学位。研究员 分子和细胞独立的基础研究事业 心血管科学。 这是一个跨跨性别的 纳入研究兴趣的部门跨部门计划和 内部部门20名教职员工的专业知识 医学，生物化学，人类遗传学， 微生物学/免疫学，病理学，药理学，生理学， 外科和大学的霍华德·休斯医学院 密歇根州。该计划的教职员工代表 杰出的分子和细胞生物学家的杰出群体 研究兴趣分为三个相关的心血管 区域：1）调节血管细胞中基因表达 强调理解细胞的分子基础 增殖，血栓形成和炎症，导致血管 病理; 2）调节基因表达的分子机制 在正常发育期间和骨骼肌中 病理生理状态； 3）心血管的基因疗法 疾病。 该培训补助金是通过心血管管理的 部门研究中心O内科。该程序 由计划主任伊丽莎白·G·纳贝尔（Elizabeth G. Nabel）和博士指导。 计划联合指导的Seigo Izumo都是成立的研究人员。 Nabel博士指导心血管研究中心和Izumo博士 是心脏病学系的负责人。培训计划是 由由高级的内部咨询委员会监督 密歇根大学的院士和领导者。 学员是M.D.，M.D./PH.D或Ph.D。博士后科学家。 第一年的四个博士后插槽，总共八个 要求2 - 5年的老虎机支持追求研究员 心血管科学的全职基础研究。每个学员 将致力于2 - 3年的研究培训。博士博士后 学员将在基本的职业生涯中拥有长期的职业兴趣 心血管科学。 M.D.和M.D./ph.d。学员会 完成了三年的内科居住培训， 以及两年的临床心脏病学培训 由密歇根大学医院完全资助。医学博士 学员参加研究生研究培训计划 当然，已建立了三个月的介绍性实验室培训 大学提供的分子和细胞生物学课程 密歇根州医学院。培训计划强烈 致力于增加妇女人数和代表性不足 接受心血管培训的少数民族个人 研究。 研究培训的设施包括 心血管研究中心和个人研究 位于大学的20个受体的实验室 MSRB III/MSRB II/MSRB I/MS I和II的密歇根州医疗中心，II 在5个连续的研究空间中包含29,847平方英尺 建筑物。完成培训计划后，学员是 指导申请独立研究资金并追求 职业作为心血管科学的独立研究者 学术医学院。