CORE--ANIMAL RESOURCES

核心——动物资源

• 批准号: 6102665
• 负责人: ROBERT WOLF
• 金额: $ 13.16万
• 依托单位: CTRC RESEARCH FOUNDATION
• 依托单位国家: 美国
• 财政年份: 1998
• 资助国家: 美国
• 起止时间: 1998-08-06 至 1999-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6102665
• 关键词: Rodentias; animal breeding; animal care; animal colony; biomedical facility; germ free condition; histopathology; postmortem; veterinary medicine

DESCRIPTION: (Applicant's Description) The Laboratory Animal Shared Resource enables SACI investigators to perform research using healthy, well conditioned laboratory animals, and specifically with rodents that are free of bacterial and viral infections, in a state-of-the-art animal facility. The achievement of this goal is assured by the operation of a model laboratory animal resource program in which careful attention is directed to the protection of colony animals from extraneous diseases and the provision of a stable environment. Careful monitoring of both newly arriving and colony-produced animals help ensure that conditions that might compromise research activities are not introduced into this facility. This vigilance specifically allows the facility to maintain large colonies of conventional, transgenic and immunocompromised rodents in good health for important biomedical research efforts. Specific research support services are also provided to individual investigators who need clinical assistance, histopathology support or other specialized services. In addition, this resource provides a wide range of other services, including: Training in handling and manipulation of research animals, including immunocompromised rodents; Professional assistance in animal model development; Technical assistance and consultation; Screening of tumor and hybridoma tissue for pathenogens; Gross and initial histopathology support; Surgical support; Specialized animal husbandry.

描述：（申请人的描述）实验室动物共享 资源使SACI调查人员能够使用健康， 条件良好的实验室动物，特别是啮齿动物 在最先进的动物中不含细菌和病毒感染 设施。通过操作确保了这个目标的实现 模型实验室动物资源计划，其中仔细注意 针对保护殖民动物免受外科疾病的保护 提供稳定的环境。仔细监视新的 到达和菌落生产的动物有助于确保 可能不会损害研究活动 设施。这种警惕使设施保持 常规，转基因和免疫功能低下的啮齿动物的大菌落 重要的是重要的生物医学研究工作。具体的 研究支持服务还向个人调查人员提供 谁需要临床帮助，组织病理学支持或其他专业 服务。 此外，此资源提供了广泛的其他服务， 包括：处理和操纵研究动物的培训， 包括免疫功能低下的啮齿动物；动物的专业协助 模型开发；技术援助和咨询；筛选 疾病的肿瘤和杂交瘤组织；总和初始 组织病理学支持；手术支持；专门的畜牧业。