TREATMENT OF GENERALIZED ANXIETY DISORDER IN THE ELDERLY

老年人广泛性焦虑症的治疗

• 批准号: 2675321
• 负责人: MELINDA A STANLEY
• 金额: $ 24.03万
• 依托单位: UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON
• 依托单位国家: 美国
• 财政年份: 1996
• 资助国家: 美国
• 起止时间: 1996-09-01 至 2001-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2675321
• 关键词: anxiety disorders; behavioral /social science research tag; clinical research; cognitive behavior therapy; depression; fear; functional ability; group therapy; human middle age (35-64); human old age (65+); human subject; human therapy evaluation; longitudinal human study; quality of life; questionnaires; social support network

DESCRIPTION (Adapted from applicant's abstract): The proposed study is a revised version of application #RO1-MH53932-01 that will examine the relative effects of cognitive behavior therapy (CBT) and a minimal contact control condition (MCC) for the treatment of generalized anxiety disorder (GAD) in older adults. The relative effects of CBT and MCC at posttreatment will be examined with regard to both primary outcome measures (global severity of GAD, worry, general anxiety) and the transfer of treatment effects to coexistent pathology (associated fears, depression) and social functioning (quality of life, social support). In addition, the impact of CBT over a long-term follow-up interval (one year) will be examined. The proposed study also will allow for exploratory examination of nonspecific predictor variables, in particular, measures of pretreatment psychopathology (anxiety, depression) and therapy process (credibility of treatment, expectancy for improvement,group cohesion, and alliance). Ninety-eight adults, 60 years or older, who meet DSM-IV criteria for GAD will be assigned randomly to CBT or MCC. Treatment will be conducted in a small group format, with 15 weekly sessions. After posttreatment evaluations at 15 weeks, patients assigned to CBT will be assessed at 3-, 6-, and 12-month follow-ups. After posttreatment assessments, MCC subjects will receive treatment with CBT and subsequent follow-up evaluations, also over a 12-month period. As such, this group will allow for indirect replication of primary study results.

描述（根据申请人的摘要改编）：拟议的研究是 修订版的应用程序＃RO1-MH53932-01，将检查 认知行为疗法（CBT）和最小接触的相对影响 治疗广义焦虑症的控制条件（MCC） （GAD）在老年人中。 CBT和MCC在治疗后的相对影响 将对两种主要结果指标进行检查（全球 GAD的严重程度，担心，一般焦虑）和治疗转移 对共存病理学（相关恐惧，抑郁）和社会的影响 功能（生活质量，社会支持）。 另外， 将检查长期随访时间（一年）的CBT。 这 拟议的研究还将允许对非特异性的探索性检查 预测变量尤其是预处理心理病理学的度量 （焦虑，抑郁）和治疗过程（治疗的信誉， 预期改善，群体凝聚力和联盟）。 九十八 符合GAD的DSM-IV标准的60岁以上的成年人将被分配 随机到CBT或MCC。 治疗将在一小组中进行 格式，每周15个会议。 经过15的治疗后评估 几周，分配给CBT的患者将在3岁，6个月和12个月中评估 后续行动。 经过治疗后评估，MCC受试者将收到 用CBT和随后的随访评估进行治疗，也是在 12个月。 因此，该组将允许间接复制 主要研究结果。