RECOVERY FROM TRAUMATIC BRAIN INJURY IN CHILDREN

儿童脑外伤的康复

• 批准号: 2039052
• 负责人: Hudson Taylor
• 金额: $ 43.02万
• 依托单位: CASE WESTERN RESERVE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-05-15 至 2001-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2039052
• 关键词: brain injury; child (0-11); clinical research; family structure /dynamics; functional ability; human subject; longitudinal human study; outcomes research; quality of life; rehabilitation; trauma

Children who sustain moderate-to-severe traumatic brain injury (TBI) are at high risk for long-term neurobehavioral sequelae. Little is known, however, about the impact of pediatric TBI on families, or the extent to which recovery from TBI is influenced by the family environment. The purpose of the proposed continuation project is to fill this void through extended follow-up of a sample of children who were hospitalizes between the ages of 6-12 years for either TBI or orthopedic injuries not involving CNS insult. The original study was designed to follow children and families over the first post-injury year. Hypothesis 1 was that TBI in this age group has more adverse and enduring effects on families than orthopedic injuries. Hypothesis 2 was that characteristics of the family environment predict child outcomes, even after injury severity and the child's pre-injury behavioral functioning are taken into account. Preliminary findings support both hypotheses and raise questions with regard to the later, adolescent outcomes of TBI compared to orthopedic injuries. In the proposed project, the majority of current study participants will return for three extended follow-up spaced at one-year intervals. The sample will include 41 children and adolescents with severe TBI, 47 with moderate TBI, and 54 with orthopedic injuries. although previous measures will be readministered and hypotheses are unchanged, additional tests of executive function and social reasoning will be given to the children to investigate later-emerging deficits in these areas. Assessments of family outcomes will also be expanded to include measures of sibling adjustment, daily phone diaries of family activities, and direct observations of parent-child interactions. Analysis will focus on group comparisons, changes over time, and predictors of outcome. Results will clarify injury sequelae, shed light on risk and protective factors, and inform efforts to reduce the long-term morbidity of TBI and other traumatic childhood injures.

遭受中度至重度创伤性脑损伤 (TBI) 的儿童 长期神经行为后遗症的高风险。 鲜为人知的是， 然而，关于儿科 TBI 对家庭的影响，或影响程度 TBI的恢复受到家庭环境的影响。 这 拟议的延续项目的目的是填补这一空白 通过对住院儿童样本进行长期随访 6-12 岁之间的 TBI 或骨科损伤不得 涉及中枢神经系统损伤。 最初的研究旨在遵循 受伤后第一年的儿童和家庭。 假设 1 是 TBI 对这个年龄段的人有更不利和持久的影响 家庭比骨科伤害。 假设 2 是 家庭环境的特征可以预测孩子的成长，甚至 受伤后的严重程度和孩子受伤前的行为功能 被考虑在内。 初步结果支持这两种假设 并对 TBI 的后期、青少年结局提出疑问 与骨科损伤相比。 在拟议的项目中，大多数 目前的研究参与者将返回进行三次长期随访 以一年为间隔。 样本将包括 41 名儿童和 患有严重 TBI 的青少年、47 名患有中度 TBI 的青少年和 54 名患有严重 TBI 的青少年 骨科损伤。 尽管之前的措施将被重新实施 假设不变，执行功能和的附加测试 将向孩子们提供社会推理以进行调查 这些领域后来出现的赤字。 家庭结局评估 还将扩大到包括兄弟姐妹调整措施、每日 家庭活动的电话日记以及直接观察 亲子互动。 分析将侧重于群体比较， 随着时间的推移而变化，以及结果的预测因素。 结果将会澄清 伤害后遗症，阐明风险和保护因素，并告知 努力降低 TBI 和其他创伤的长期发病率 童年受伤。