QUALITY OF WELL BEING (QWB) SCALE REVISION PROJECT

福祉质量 (QWB) 量表修订项目

• 批准号: 2032029
• 负责人: Robert M Kaplan
• 金额: $ 23.1万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 财政年份: 1997
• 资助国家: 美国
• 起止时间: 1997-08-01 至 2000-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2032029
• 关键词: behavioral /social science research tag; cataract surgery; clinical research; eye prosthesis; health care cost /financing; health care policy; health care service evaluation; health services research tag; human subject; outcomes research; preference; quality of life; questionnaires; vision disorders

DESCRIPTION: The specific aims of the proposed project are: to develop and validate a self-administered form of the QWB, referred to as the QWB-SA; to perform preference measurement studies in order to obtain a scoring system for the QWB-SA; and to develop a vision specific scoring system for the QWB-SA. Aim 1: Develop and validate QWB-SA. Aim 1 involves several steps. First the investigators will expand on the current list of symptoms in the QWB. A draft of the QWB-SA (already developed) will be sent to 15 experts for review and comment. Next, a content analysis of the HRQL literature will be performed to determine the degree to which the QWB-SA adequately captures items included in existing measures. After further revisions of the QWB are complete, the QWB-SA will be pilot tested at the UCSD Multipurpose Arthritis Center, and with patients in Family Medicine Clinics. Next, the measure will be field tested in ongoing studies at UCSD and in clinical research centers. In addition, a stratified random sample of 10 percent (200) will be selected for further study. These 200 patients will complete the interviewer administered QWB and the SF-36, with appropriate counterbalancing and administration at two time points with about one-month separation. A qualitative analysis for assessing the accuracy of information developed in the surveys will be performed on the 200 patients' data, using the Internal Consistency Analysis method. Additional analyses of the full 2,000, and the subset of 200, will include: item analysis to assess missing data rates and frequency distributions for all items; comparisons of mean QWB and QWB-SA scores; correlation analyses of all components of the QWB, QWB-SA and SF-36 to determine which of the QWB's is most correlated with the SF-36; and subanalyses of the QWB-SA by demographic variables, including age, gender, and education. Profile scoring of the QWB will be performed using factor analyses, with expected clusters including: physical activity, social activity, self-care, mobility, pain, emotional functioning, and sensory functioning. Factor scores will be created by obtaining the sum of item responses and factor score coefficients separately for each dimension. Aim 2: Preference measurement study to obtain a scoring system for the QWB-SA. Five hundred patients from the primary care clinics at the UCSD will be recruited into this phase of the proposed research. They will be evenly divided by gender, all will be adults, and about 40 percent will be African American or Hispanic. All participants will rate complete case descriptions and components of different health states, using a 1-100 point scale. Analyses of the preference data will involve two phases: establishment of the interval scale property and the development of the model of judgment; and, estimation of value weights. Aim 3: Disease-specific versus general measure. In this phase of the study, the investigators propose to develop a vision specific scoring system for the QWB-SA. Two hundred fifty patients undergoing their first eye cataract extraction will be recruited into the study. Participants must be older than 35 years of age. Exclusion criteria include: inability to speak English; serious hearing impairment; cognitive impairment; patients undergoing simultaneous glaucoma, corneal or vitro-retinal procedures; patients with traumatic cataracts; and patients with visual impairment so severe that they cannot complete a self-administered form. In addition to the QWB-SA data, data will be collected on visual acuity and patients will complete the VF-14, a functional status measure designed specifically for visual problems. Also, a cataract symptom score scale and a brief medical co-morbidity scale will be administered to the patients. Psychometric methods will be used to evaluate items from the QWB-SA and the vision-specific measures in relation to visual acuity and a vision specific outcome measure.

描述：拟议项目的具体目的是：开发和 验证QWB的自我管理形式，称为QWB-SA；到 进行偏好测量研究以获得评分系统 对于QWB-SA；并开发一个特定的评分系统 QWB-SA。 目标1：开发和验证QWB-SA。 AIM 1涉及几个步骤。 第一的 研究人员将扩大QWB中当前症状清单。 一个 QWB-SA的草案（已经开发）将发送给15位专家 评论和评论。 接下来，将对HRQL文献进行内容分析 执行以确定QWB-SA充分捕获的程度 现有措施中包括的项目。 经过QWB的进一步修订后 完整，QWB-SA将在UCSD多功能关节炎上进行试验。 中心，以及家庭医学诊所的患者。 接下来，措施 将在UCSD和临床研究的正在进行的研究中进行现场测试 中心。 另外，分层的随机样本为10％（200） 被选为进一步研究。 这些200名患者将完成 访调员管理QWB和SF-36，并适当 分两个时间点的平衡和管理大约一个月 分离。 评估开发信息准确性的定性分析 在调查中，将对200名患者的数据进行。 内部一致性分析方法。 完整的其他分析 2,000和200的子集将包括：评估丢失的项目分析 所有项目的数据速率和频率分布；平均值的比较 QWB和QWB-SA分数； QWB的所有组件的相关分析， QWB-SA和SF-36确定哪个QWB与 SF-36;和QWB-SA的亚台词，包括人口统计学变量，包括 年龄，性别和教育。 将执行QWB的配置文件评分 使用因子分析，具有预期簇，包括：体育活动， 社交活动，自我保健，流动性，痛苦，情感功能以及 感官功能。 通过获得的总和，将创建因子得分 每个维度的项目响应和因子得分系数分别。 AIM 2：偏好测量研究以获取针对该评分的系统 QWB-SA。 来自UCSD的初级保健诊所的五百名患者 将招募到拟议的研究的这一阶段。 他们会的 按性别平均分配，所有这些都是成年人，约40％将是 非裔美国人或西班牙裔。 所有参与者都将对案例进行评分 使用1-100点的不同健康状况的描述和组成部分 规模。 对偏好数据的分析将涉及两个阶段： 建立间隔规模的财产和发展 判断模式；并且，价值权重的估计。 AIM 3：特定于疾病与一般度量。 在这个阶段 研究，研究人员建议开发特定视觉的评分系统 对于QWB-SA。 250名患者正在接受他们的第一只眼睛 白内障提取将招募到研究中。 参与者必须是 超过35岁的年龄。 排除标准包括：无法说话 英语;严重的听力障碍；认知障碍；患者 同时接受青光眼，角膜或体外视网膜手术； 创伤性白内障患者；和视觉障碍的患者 严重的是他们无法完成自我管理的形式。 此外 QWB-SA数据，将收集有关视力的数据，患者将 完成VF-14，这是专门设计的功能状态度量 视觉问题。 此外，白内障症状评分量表和简短的医疗 合并症量表将向患者施用。 心理测量学 方法将用于评估QWB-SA和 与视力和视力相关的视力特定措施 结果度量。