Advancing Alzheimer's Disease Communication and Recruitment Science among American Indians and Alaska Natives

促进美洲印第安人和阿拉斯加原住民之间的阿尔茨海默病传播和招募科学

• 批准号: 10596112
• 负责人: Amanda D. Boyd
• 金额: $ 11.92万
• 依托单位: WASHINGTON STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-05-01 至 2026-02-28
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10596112
• 关键词: Acceleration; Adherence; Adult; Affect; Age; Aging; Alaska Native; Alzheimer' s Disease; Alzheimer' s disease related dementia; Alzheimer' s disease risk; American; American Indians; Asian population; Attention; Behavior; Clinical Research; Clinical Treatment; Clinical Trials; Cognitive; Communication; Communication Methods; Complement; Computers; Consumption; Cultural Sensitivity; Data; Data Collection; Development; Education; Elderly; Electromyography; Emotional; Enrollment; Eye Movements; Face; Funding; Future; Galvanic Skin Response; General Population; Goals; Grant; Guidelines; Health; Health Disparities Research; Health Policy; Healthcare; Heart Rate; Image; Imagery; Instruction; Internet; Interview; Knowledge; Measures; Mentors; Methods; Minority Participation; Minority Recruitment; National Institute on Aging; Not Hispanic or Latino; Outcome; Participant; Patient Recruitments; Patient Self-Report; Pattern; Persons; Pilot Projects; Population; Population Heterogeneity; Positioning Attribute; Prevalence; Process; Protocols documentation; Psychophysiology; Questionnaires; Race; Randomized; Randomized, Controlled Trials; Reaction; Reader; Reading; Reporting; Research; Research Methodology; Research Personnel; Resources; Respondent; Scanning; Self Assessment; Shapes; Site; Source; Structure; Surveys; Testing; Text; Training; Underserved Population; United States National Institutes of Health; Variant; Visual; Writing; career development; design; digital communication; digital technology; effective therapy; effectiveness trial; experience; falls; health communication; information seeking behavior; innovation; novel; preference; preventive intervention; primary outcome; randomized trial; recruit; recruitment science; research study; response; success; visual tracking; web site; willingness

PROJECT SUMMARY/ABSTRACT Alzheimer’s disease and related dementias (ADRD) affects 5.5 million Americans. The number of people in the US with ADRD is expected to increase to 16 million by 2050 unless preventive interventions and effective treatments are developed. Despite advances in ADRD research among non-Hispanic Whites, little is known about the prevalence and risk factors for ADRD in American Indian and Alaska Native (AI/AN) populations. This is in part due to low participation of AI/ANs in ADRD research. The National Institute on Aging and the Alzheimer’s Association have issued calls for an increase in minority participation in clinical trials. However, success has been evasive in efforts to recruit AI/AN populations into ADRD clinical studies. The internet is a primary method for providing information about ADRD and recruiting participants into clinical studies. AI/ANs frequently use the internet for health information but also report that the websites they access lack cultural sensitivity. To increase AI/AN participation in ADRD research, it is critical to understand how AI/ANs consume and process online information. This information can be used to create effective communication and recruitment material for ADRD clinical studies. In this K01, we will apply a multi-method approach to assess how AI/ANs process and consume online material. Using this information, we will create culturally tailored online content to educate AI/ANs about ADRD to promote their enrollment into ADRD research. Our Specific Aims are to: 1) conduct psychophysiology testing and semi-structured interviews to characterize visual website search patterns, objectively measured cognitive and emotional responses, knowledge about ADRD and research, and preferences for accessing health information online; 2) create a culturally tailored educational ADRD website for AI/ANs that offers research opportunities and conduct a pilot study to demonstrate feasibility of a future randomized controlled trial; and 3) complete a rigorous training plan that will position the applicant as an independent investigator and leader in communication with underserved populations, especially AI/ANs. This innovative application provides an opportunity to discover critical information about how AI/ANs process information and answers the National Institute on Aging’s call for research to better understand effective strategies for recruiting minorities into ADRD research and communicating health messages that are appropriate for diverse populations.

项目概要/摘要 阿尔茨海默病及相关痴呆症 (ADRD) 影响着 550 万美国人。 除非采取预防性干预措施和有效的措施，否则到 2050 年，美国患有 ADRD 的人数预计将增加到 1600 万 尽管非西班牙裔白人 ADRD 研究取得了进展，但人们知之甚少。 关于美洲印第安人和阿拉斯加原住民 (AI/AN) 人群 ADRD 的患病率和危险因素。 部分原因是 AI/AN 在 ADRD 研究中的参与度较低。 阿尔茨海默病协会呼吁增加少数群体参与临床试验。 招募 AI/AN 人群参与 ADRD 临床研究的努力一直难以取得成功。 提供有关 ADRD 信息和招募 AI/AN 参与者的主要方法。 经常使用互联网获取健康信息，但也报告说他们访问的网站缺乏文化 为了增加 AI/AN 对 ADRD 研究的参与，了解 AI/AN 的消费方式至关重要。 并处理在线信息可用于创建有效的沟通和招聘。 ADRD 临床研究材料 在本 K01 中，我们将应用多种方法来评估 AI/AN 的效果。 使用这些信息，我们将创建适合文化的在线内容。 对 AI/AN 进行 ADRD 教育，以促进他们参与 ADRD 研究。我们的具体目标是：1) 进行心理生理学测试和半结构化访谈来表征视觉网站搜索模式， 客观测量认知和情绪反应、有关 ADRD 和研究的知识，以及 在线访问健康信息的偏好；2) 创建一个适合文化的 ADRD 教育网站 AI/AN 提供研究机会并进行试点研究以证明未来的可行性 随机对照试验；3) 完成严格的培训计划，将申请人定位为 与服务不足的人群（尤其是 AI/AN）沟通的独立调查员和领导者。 创新应用程序提供了发现有关 AI/AN 如何处理的关键信息的机会 信息并回应国家老龄化研究所的研究呼吁，以更好地了解有效性 招募少数群体参与 ADRD 研究并传播适当的健康信息的策略 适合不同人群。