EFFECTS OF MATERNAL PHENYLKETONURIA ON PREGNANCY OUTCOME

母亲苯丙酮尿症对妊娠结局的影响

• 批准号: 2314916
• 负责人: Harvey L. Levy
• 金额: $ 41.78万
• 依托单位: BOSTON CHILDREN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 1992
• 资助国家: 美国
• 起止时间: 1992-05-01 至 1996-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2314916
• 关键词: EFFECTS; MATERNAL; PHENYLKETONURIA; PREGNANCY; OUTCOME

The primary purpose of this project is to determine the best method of managing women during pregnancy who have hyperphenylalaninemia (HPA) including: classical phenylketonuria (PKU) - blood phenylalanine concentrations of more than 20 mg/dl while on a normal diet; variant PKU - 10-20 mg/dl; or benign HPA - 4-10 mg/dl. Fetal morbidity, with subsequent problems in growth and development, associated with maternal PKU will be assessed in relation to maternal phenylalanine levels.

该项目的主要目的是确定 在怀孕期间患有苯基丙氨酸血症（HPA）的妇女 包括：经典苯酮尿症（PKU） - 血苯丙氨酸 在正常饮食中，浓度超过20 mg/dl；变体PKU- 10-20 mg/dl;或良性HPA -4-10 mg/dl。 胎儿发病率 随后在增长和发展方面的问题，与母亲有关 PKU将根据母体苯丙氨酸水平进行评估。