UNC Geriatric Oncology Training Grant (UNC-GO)

北卡罗来纳大学老年肿瘤学培训补助金（UNC-GO）

基本信息

批准号：
10541849
负责人：
JAN BUSBY-WHITEHEAD
金额：
$ 13万
依托单位：
UNIV OF NORTH CAROLINA CHAPEL HILL
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-01-01 至 2023-12-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10541849
关键词：
Elderly Grant Oncology Training

项目摘要

ABSTRACT Cancer is a disease of aging, with incidence and mortality rates rising dramatically with increasing age. In the U.S., the average age at a cancer diagnosis is 66 years; of the 1,688,780 new cancer cases in 2017, more than 53% are adults age 65 years and older. Sixty-two percent of current survivors are age >65, and will rise to 73% by 2040. These numbers, coupled with aging trends of the U.S. population, portend large and growing cohorts of older cancer patients and survivors in the years to come. Cancer treatment in the older population is challenging and complicated by factors related to co-morbidity, functional status, polypharmacy, social support, nutritional status, and other geriatric relevant domains. Our ability to provide personalized and appropriate cancer care to our rapidly expanding older population is challenged by a shortage of geriatricians to team with oncologists, inadequate geriatrics training of oncologists, and cancer clinical trials that have focused largely on younger patients and have generated little data on elders who are more likely to have multiple comorbidities and varying goals of care. The UNC Geriatric Oncology Training Grant (UNC-GO) is a T32 training application from the University of North Carolina at Chapel Hill (UNC) specifically focused on training physicians in clinical/translational or health services research at the interface of geriatrics and oncology. Co-directed by renowned leaders in oncology (Hyman B. Muss, MD) and geriatrics (Jan Busby-Whitehead, MD), UNC-GO will provide two years of training (one new trainee per year) in geriatric oncology research for residents and fellows training in Geriatrics or Medical, Surgical, Gynecologic, Radiation, or Urologic Oncology. UNC-GO trainees will benefit from access to resources and expertise available through the UNC Lineberger Comprehensive Cancer Center (UNC-LCCC), which received an “exceptional” score of 11 during its most recent review, as well as the UNC-LCCC Geriatric Oncology Program (co-directed by Drs. Muss and Busby-Whitehead) and the UNC Center on Aging and Health (director by Dr. Busby-Whitehead). UNC-GO primary preceptors are UNC-LCCC members and have on average $1.1 million in annual research funding. Upon the trainee’s admission to the program, the UNC-GO Co-Directors and Steering Committee work with the trainee to form a mentorship team that includes a clinician/scientist with Geriatrics expertise. The central component of UNC-GO training is the mentored research experience. Trainees will choose between two research tracks that represent the best research areas that UNC has to offer: clinical/translational and health services research. Under the guidance of the mentoring team, trainees design and conduct one or more independent projects. Trainees address aspects of research ranging from developing the research question and design, to the protocol, methods, instruments, data collection/compilation, data management, analysis, and reporting. Involvement of collaborating experts is expected. Trainees are expected to present their research findings at local, regional, and national scientific meetings, and to have a minimum of one first-author manuscript submitted per year.

抽象的癌症是一种衰老性疾病，其发病率和死亡率随着年龄的增长而急剧上升。美国 2017 年新增癌症病例 1,688,780 例，平均诊断年龄为 66 岁； 53% 是 65 岁及以上的成年人，目前幸存者中的 62% 年龄 >65 岁，并将上升至 73%。到 2040 年。这些数字，加上美国人口的老龄化趋势，预示着人口规模庞大且不断增长未来几年老年癌症患者和幸存者的癌症治疗是。与合并症、功能状态、多药治疗、社会支持相关的因素具有挑战性和复杂性，营养状况以及其他老年相关领域我们提供个性化和适当癌症的能力。对我们快速增长的老年人口的护理面临着缺乏老年科医生的挑战肿瘤科医生的老年病学培训不足，以及癌症临床试验主要集中在年轻患者的数据很少，关于老年人的数据很少，老年人更有可能患有多种合并症，北卡罗来纳大学老年肿瘤学培训补助金 (UNC-GO) 是一项 T32 培训申请。北卡罗来纳大学教堂山分校 (UNC) 特别注重培训医生老年病学和肿瘤学交叉领域的临床/转化或健康服务研究。肿瘤学（Hyman B. Muss，医学博士）和老年医学（Jan Busby-Whitehead，医学博士）领域的知名领导者，UNC-GO 将为住院医师和研究员提供两年的老年肿瘤学研究培训（每年一名新学员）老年病学或内科、外科、妇科、放射或泌尿肿瘤学培训。受益于通过北卡罗来纳大学莱恩伯格综合癌症中心获得的资源和专业知识中心 (UNC-LCCC)，在最近的审查中获得了 11 分的“优异”分数，以及 UNC-LCCC 老年肿瘤学项目（由 Muss 博士和 Busby-Whitehead 博士共同指导）和 UNC 中心 UNC-GO 的主要导师是 UNC-LCCC 成员。受训者加入该项目后，平均每年获得 110 万美元的研究经费。 UNC-GO 联合主任和指导委员会与学员合作，组建了一个导师团队，其中包括具有老年病学专业知识的临床医生/科学家。 UNC-GO 培训的核心部分是指导研究。学员将在代表北卡罗来纳大学最佳研究领域的两个研究方向之间进行选择。必须提供：临床/转化和健康服务研究在指导团队的指导下，受训者设计并开展一个或多个独立项目。受训者涉及研究范围的各个方面。从制定研究问题和设计，到协议、方法、仪器、数据收集/编译、数据管理、分析和报告是合作专家的参与。预计学员将在地方、区域和国家科学界展示他们的研究成果。会议，并每年至少提交一份第一作者手稿。

项目成果

期刊论文数量（5）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Supportive Care and Symptom Management for Patients With Immunoglobulin Light Chain (AL) Amyloidosis.

免疫球蛋白轻链 (AL) 淀粉样变性患者的支持护理和症状管理。

DOI：
发表时间：
2022
期刊：
影响因子：
0
作者：
Jensen, Christopher E;Byku, Mirnela;Hladik, Gerald A;Jain, Koyal;Traub, Rebecca E;Tuchman, Sascha A
通讯作者：
Tuchman, Sascha A

Risk factors for atypical hyperplasia and endometrial cancer in the infertility population: a case-control study.

不孕人群中不典型增生和子宫内膜癌的危险因素：病例对照研究。