Estimating acute impacts of unconventional oil and gas development on cause-specific hospitalization via satellite-based exposure assessment

通过基于卫星的暴露评估评估非常规石油和天然气开发对特定原因住院治疗的严重影响

• 批准号: 10507465
• 负责人: Longxiang Li
• 金额: $ 10.21万
• 依托单位: HARVARD SCHOOL OF PUBLIC HEALTH
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-01 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10507465
• 关键词: Acute; Air Pollutants; Award; Chronic; Columbidae; Communities; Computer software; Crude Extracts; Data; Data Analyses; Decentralization; Development; Environment; Environmental Health; Exposure to; Funding; Gases; Generations; Health; Health Status; Hospitalization; Image; Image Analysis; Imagery; Investigation; Measures; Mediating; Mediator of activation protein; Medicare; Methods; Modeling; Monitor; Natural Gas; Observational Study; Oils; Outcome; Participant; Petroleum; Phase; Procedures; Process; Production; Proxy; Records; Refuse Disposal; Research Personnel; Resolution; Risk; Rural; Sentinel; Site; Source; TimeLine; Training; Transportation; base; beneficiary; career; cohort; epidemiology study; exposure pathway; high resolution imaging; improved; novel; open source; pollutant; predictive modeling; prevent; remote sensing; rural area; skills; spatiotemporal; temporal measurement

Project summary Onshore expansion of Unconventional oil and gas development (UOGD) is considered an emerging environmental health issue due to its disproportional proliferation in rural U.S communities and the potential health impacts on 23 million nearby residents. However, two critical gaps in exposure assessment have restricted previous studies from achieving rigorous and actionable evidence regarding the acute health effects of UOGD construction stages. First, current exposure assessments were too coarse to accurately capture the short-term variability in exposure. Due to a lack of detailed construction records, investigators had to impute construction timelines for most wells based on questionable assumptions, which likely introduce misclassification. Second, none of prior large-scale observational studies has quantified exposure to specific UOGD-sourced pollutant. Investigators instead have developed various surrogates, which proxy residential exposure with functions of auxiliary factors (e.g., distance to UOGD wells). These exposure surrogates do not account for the different transports and fates of UOGD-sourced pollutants in ambient environment, thus cannot indicate specific exposure pathway(s). Furthermore, causal inference, which provide a rigorous adjustment for confounding, have not been widely used in estimating UOGD’s health effects. The objective of this proposal is to investigate the acute health effects of UOGD constructions based on improved satellite-based exposure assessment. In the K99 phase, I will take advantage of high-resolution images obtained by multiple recently launched satellites, including Sentinel-1s, Sentinel-2s, and Dove satellites to automatically detect the daily construction stage of UOGD wells (Aim 1). Multiple state-of-art causal inferential methods will be used to estimate the acute effects of each UOGD construction stage on the risk of cause-specific hospitalization in Medicare beneficiaries based on the new exposure assessment (Aim 2).In the R00 phase, I will develop and validate new exposure metrics based on the daily concentrations of air pollutants near UOGD wells, which are observed by Sentinel 5P (Aim3). Finally, I will explore the extent to which UOGD-related air pollutants mediate any effect of UOGD construction stages (Aim4). The expected outcomes are 1) an open-source software to detect UOGD-related activities from remote sensing images; 2) exposure metrics for UOGD-related air pollutants; 3) acute causal health effects of UOGD construction. The exposure data will be made public available to advance the field.

项目概要 非常规石油和天然气开发（UOGD）的陆上扩张被认为是一种新兴的 由于其在美国农村社区的不成比例扩散和潜在的环境健康问题 对 2300 万附近居民的健康影响 然而，暴露评估存在两个关键缺陷。 限制了之前的研究获得关于急性健康影响的严格且可操作的证据 首先，当前的暴露评估过于粗略，无法准确捕捉到。 由于缺乏详细的施工记录，研究人员不得不估算暴露的短期变化。 大多数油井的施工时间表基于有问题的假设，这可能会导致 其次，之前的大规模观察研究都没有量化特定的暴露程度。 相反，研究人员开发了各种替代物，用于替代住宅。 具有辅助因素功能的暴露（例如，与 UOGD 井的距离） 这些暴露替代项不具有影响。 解释 UOGD 来源的污染物在周围环境中的不同迁移和归宿，因此无法 表明具体的暴露途径此外，因果推断为以下提供了严格的调整。 混杂因素尚未广泛用于估计 UOGD 的健康影响 该提案的目的是。 基于改进的卫星曝光研究 UOGD 结构对健康的急性影响 在K99阶段，我将利用最近获得的多个高分辨率图像。 发射卫星，包括Sentinel-1、Sentinel-2、Dove卫星，自动检测日常 UOGD 井的施工阶段（目标 1）将使用多种最先进的因果推理方法。 评估每个 UOGD 建设阶段对特定原因住院风险的急性影响 医疗保险受益人基于新的暴露评估（目标 2）。在 R00 阶段，我将制定和 根据 UOGD 井附近空气污染物的每日浓度验证新的暴露指标，这些指标是 最后，我将探讨与 UOGD 相关的空气污染物的介导程度。 UOGD 构建阶段（目标 4）的任何影响 预期结果是 1) 一个开源软件 从遥感图像中检测 UOGD 相关活动；2) UOGD 相关空气的暴露指标 污染物；3）UOGD 施工对健康造成的急性影响 暴露数据将予以公开。 可用于推进该领域。