Washington Entrepreneurial Research Evaluation and Commercialization Hub

华盛顿创业研究评估和商业化中心

• 批准号: 10475213
• 负责人: RODNEY J.Y. HO
• 金额: $ 99.45万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-23 至 2024-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10475213
• 关键词: Acquired Immunodeficiency Syndrome; Biological Sciences; Biomedical Research; Biotechnology; Businesses; Child; Cities; Climacteric; Collaborations; Communities; Databases; Development; Drug Interactions; Environment; Evaluation Research; Expenditure; Fostering; Foundations; Fred Hutchinson Cancer Research Center; Fruit; Funding; Gardasil; Generations; Genetic; Genetic Engineering; Goals; Governing Board; Health; Health Alliance; Health Sciences; Hepatitis B Vaccines; Hepatitis B Virus; Human Papillomavirus; Individual; Industry; Infectious Diseases Research; Infrastructure; Institutes; Institution; Insulin; Intellectual Property; International; Investments; Lead; Leadership; Legal; Legal patent; Licensing; Market Research; Marketing; Medical Device; Mentors; Mentorship; Outcome; Pacific Northwest; Pathway interactions; Persons; Pharmacologic Substance; Process; Protein Engineering; Public Health; Recombinant Proteins; Recombinants; Recording of previous events; Research; Research Institute; Research Personnel; Research Support; Resources; Schools; Scientist; Services; Somatotropin; Somatropin; Structure; System; Talents; Technology; Technology Transfer; Therapeutic; Training; Translational Research; Translations; United States; United States National Institutes of Health; Universities; Vaccines; Washington; Work; Yeasts; base; burden of illness; clinical development; commercialization; design; disability; global health; health economics; health organization; improved; innovation; next generation; polypeptide; product development; professor; programs; success; translational health science

The University of Washington and the entrepreneurial community seeks to partner with the National Institutes of Health to become a Research Evaluation and Commercialization Hub (REACH) to accelerate academic biomedical discoveries into products helping ease the highest U.S. burden of disease and disability. The UW is a powerhouse in health sciences, technology, and innovation in a city known for seeking solutions to the most pressing health problems around the world. The University’s long-standing relationship with the entrepreneurial business community has helped in the formation of Boeing, Microsoft, Amazon, Immunex, Zymogenetics, Teblos, the Drug Interaction Database, and Seattle Genetics. It’s also led to well-recognized recombinant therapeutic and vaccine products such as growth hormone, insulin, RecombiVax HB®, and Gardasil®. Many of our graduates work at major health organizations in the city, including The Gates Foundation, Path, Fred Hutchinson Cancer Research Center, the Infectious Disease Research Institute. The University’s Foster School of Business gathers business leaders to judge and mentor solutions to health problems, and major business leaders are part of the governing board of these organizations and the networking hub The Washington Global Health Alliance and The Innovation Hub of Life Sciences Washington. In this rich spirt of collaboration, a hub to accelerate promising biomedical discoveries would fit right in. A hub is needed to further energize the spirit of discovery and collaboration and overcome barriers in getting products to the public. A hub will leverage existing resources for translational research and support the journey to fruition to innovative products that change lives. With institutional co-funding commitments, strong support of community leaders, and proven leadership in entrepreneurial startups, the four Aims of this proposal are to (1) Develop an integrated infrastructure and implementation system; (2) Identify the most promising technologies, and increase their availability using milestone-driven gap funding and mentoring (in business, marketing, and networking) for market-driven proof-of-product concept and product definition; (3) Fuel the formation of new biotechnology, pharmaceutical, and medical device companies, and assist in pathways to a self-sustaining structure; (4) Train the next generation of biomedical entrepreneurs to lead these ventures. With NIH support, this hub will accelerate the creation of small businesses using biomedical discoveries to launch products that impact health outcomes. An investment in the Pacific Northwest will amplify the returns on this funding due to the critical mass of investigators, and the will of our institutions to make this happen.

华盛顿大学和创业界寻求与国家研究院合作 健康部将成为研究评估和商业化中心（REACH）以加速学术发展 产品的生物医学发现有助于减轻美国最严重的疾病和残疾负担。 威斯康星大学是健康科学、技术和创新领域的强国，位于一座以寻求解决方案而闻名的城市 解决世界各地最紧迫的健康问题。 大学与创业商业界的长期关系有助于 成立了波音、微软、亚马逊、Immunex、Zymo Genetics、Teblos、药物相互作用数据库，以及 西雅图遗传学公司还推出了广受认可的重组治疗和疫苗产品，例如生长剂。 激素、胰岛素、RecombiVax HB® 和 Gardasil®。 我们的许多毕业生在该市的主要卫生组织工作，包括盖茨基金会、Path、 弗雷德·哈钦森癌症研究中心、福斯特大学传染病研究所。 商学院聚集商界领袖来判断和指导健康问题和主要问题的解决方案 商业领袖是这些组织和网络中心的理事会的一部分 华盛顿全球健康联盟和华盛顿生命科学创新中心。 本着这种丰富的合作精神，加速有前途的生物医学发现的中心将非常适合。 需要进一步激发发现和协作精神并克服获取产品的障碍 中心将利用现有资源进行转化研究并支持这一旅程。 在机构的共同资助承诺和强有力的支持下，我们成功实现了改变生活的创新产品。 社区领袖，以及在创业型初创公司中经过验证的领导力，该提案的四个目标是（1） 开发集成的基础设施和实施系统；（2）确定最有前途的技术， 并利用里程碑驱动的缺口资金和指导（在商业、营销和 （三）促进新动能的形成 生物技术、制药和医疗器械公司，并协助实现自我维持的途径 结构；（4）培训下一代生物医学企业家来领导这些企业。 在 NIH 的支持下，该中心将利用生物医学发现加速小型企业的创建 推出影响健康结果的产品在太平洋西北地区的投资将增加回报。 这笔资金是由于大量的调查人员以及我们的机构实现这一目标的意愿。

项目成果

Data-driven design of a multiplexed, peptide-sensitized transistor to detect breath VOC markers of COVID-19.

数据驱动的多路复用肽敏化晶体管设计，用于检测 COVID-19 的呼吸 VOC 标记物。

• 发表时间: 2023-06-01
• 影响因子: 12.6
• 作者: Nakano;Fong, Hanson;Shukla, Shalabh;Lee, Richard V;Cai, Le;Godin, Dennis;Hennig, Tatum;Rath, Siddharth;Novosselov, Igor;Dogan, Sami;Sarikaya, Mehmet;MacKenzie, J Devin
• 通讯作者: MacKenzie, J Devin