CONTAINMENT FACILITIES FOR ANIMAL HOUSING AND RESEARCH

动物饲养和研究的收容设施

• 批准号: 3059320
• 负责人: MICHAEL DINGERSON
• 金额: $ 7.98万
• 依托单位: UNIVERSITY OF MISSISSIPPI
• 依托单位国家: 美国
• 财政年份: 1992
• 资助国家: 美国
• 起止时间: 1992-09-30 至 1994-03-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/3059320
• 关键词: animal care; biomedical facility; building /facility design /renovation

The University of Mississippi's Animal Resource Program has undergone a major reorganization and redefinition of priorities. Several factors have contributed to these changes, but the two primary influences are a) the movement toward administrative centralization; and b) a refining and reorientation of the University's biomedical research programs, with a major focus on Drug Discovery. The School of Pharmacy's program in Drug Discovery and Development has grown dramatically, with increasing focus on discovery of new anti-infective agents. This program has succeeded in attracting major federal funding initiatives, the capstone of which is the National Center for the Technological Development of Natural Products. This Center is slated for completion in 1995, and will include the University's new state-of-the-art laboratory animal facilities. These facilities, along with a complete program staff with appropriate support and monitoring of the University's animal usage, have been one of our long- range goals for the Animal Resource Program. In the interim, in preparation for the transition to that facility and staffing arrangement, the Animal Resource Program has identified essential short term goals to upgrade existing facilities, to provide humane, professional, and safe conditions for animal housing/usage, and for appropriate support for current growth of research efforts. Specifically it is proposed to upgrade and expand the capability for our researchers to work with animal models of infectious disease. Toward the end, this application requests funding for equipping two of our existing animal rooms with: a) three animal isolator housing systems; b) a Class II biohazard containment hood for research procedures in rodents; and c) two autoclaves for decontamination of bedding, caging, and other housing materials, and for sterilization/decontamination of animal procedure room supplies and instruments, respectively. In this interim period (1992-1995), it is critical that this institution maintain and extend its commitment to the provision of suitable facilities in support of our animal research programs in biomedical science.

密西西比大学的动物资源计划已经进行了 重点重组和重新定义优先级。 有几个因素 为这些变化做出了贡献，但两个主要影响是a） 行政集中化的运动； b）精炼和 重新定位大学的生物医学研究计划， 对药物发现的主要关注。 药学院的药物计划 发现与发展急剧增长，越来越关注 发现新的抗感染剂。 这个程序已经成功 吸引了主要的联邦资金计划，其顶峰是 国家天然产品技术发展中心。 该中心计划于1995年完成，并将包括 大学新的最先进的实验室动物设施。 这些 设施，以及完整的计划人员并提供适当的支持 并监视大学的动物使用情况，一直是我们长期的 动物资源计划的范围目标。 在过渡期间，为过渡到该设施的准备 人员配备安排，动物资源计划已经确定了必不可少的 短期目标以升级现有设施，提供人道， 专业且安全的动物住房/使用条件，用于 适当支持研究工作的当前增长。 特别是提议升级和扩展我们的能力 研究人员使用传染病动物模型。走向 最后，本申请要求资金为我们现有的两个 具有以下方式的动物室：）三个动物隔离器壳体系统； b）II类 生物危害遏制引擎盖用于啮齿动物的研究程序；和c）两个 用于覆盖床上用品，笼子和其他住房的高压灭绝 材料，用于灭菌/动物程序室的净化 供应和工具。 在这个临时时期（1992-1995），这个机构至关重要 维护并扩展其对提供合适设施的承诺 支持我们生物医学科学领域的动物研究计划。