Core F: Biostatistics and Bioinformatics

核心F：生物统计学和生物信息学

• 批准号: 10457631
• 负责人: Robert H Lyles
• 金额: $ 64.25万
• 依托单位: EMORY UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-30 至 2027-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10457631
• 关键词: Acquired Immunodeficiency Syndrome; Advocate; Applications Grants; Area; Award; Behavioral; Bioinformatics; Biometry; Case Report Form; Clinical; Clinical Research; Collaborations; Consultations; Data; Data Analytics; Development; Doctor of Philosophy; Ensure; Epidemic; Faculty; Fostering; Funding; Future; Goals; Grant; HIV; Infectious Diseases Research; Leadership; Link; Mentorship; Methodology; Mission; Modernization; Participant; Positioning Attribute; Publications; Registries; Research; Research Design; Research Methodology; Research Personnel; Role; Science; Seeds; Services; Statistical Methods; System; Talents; Time; Training; Universities; base; career development; database design; design; epidemiology study; innovation; member; next generation; programs; ranpirnase; recruit; social; sound; success; synergism; working group

PROJECT SUMMARY/ABSTRACT The Biostatistics and Bioinformatics (Bios) Core (Core F) provides CFAR Members with access to a highly qualified team of faculty and staff (core members) who are expert key players in team-based science. The goals for populating and deploying this team are to respond to the traditional biostatistical and bioinformatic service needs of CFAR Members, while maintaining capacity for innovation in terms of developing and employing cutting edge methodology toward statistical design and analytic challenges that arise in modern clinical, basic, translational, and social and behavioral epidemiologic research. The Bios Core enhances the impact and rigor of HIV-related research conducted by CFAR Members through collaboration and consultation, as well as through training and mentorship activities that emphasize the career development of new investigators. An innovative Bios Core Liaison system, implemented in 2016, has matured over the current funding period to facilitate the linking of targeted Bios Core faculty members with all science Cores and Scientific Working Group members. The Core offers a complete suite of services that provide support for proposal development, study design, data analytic plans, case report form and database design, and the publication of scientific research. In the next project period, the Bios Core will continue to prioritize emerging HIV researchers through its collaborations with the Developmental Core's pilot grant programs and with the Clinical Research Core to support proposal development and effective use of registry-based data. At the same time, we will foster and strengthen long-term collaborations with established CFAR Members to promote innovative and impactful team science. The Bios Core will focus its activities on the following Specific Aims: Aim 1: Deliver high quality collaborative support to CFAR Members, with particular emphasis on supporting and enhancing the proposals of early-stage HIV investigators; Aim 2: Leverage Core members' specialized expertise in support of the Emory CFAR's overall mission, to develop long-term and self-sustaining scientific collaborations in transdisciplinary research; Aim 3: Enhance both inter- and intra-CFAR synergy through engagement activities designed to promote and disseminate innovative and impactful HIV-related research methods and practice; Aim 4: Promote the next generation of Bios faculty to Core leadership positions and engage talented trainees to ensure the Core's continued long-term success in enhancing CFAR Members' research through sound and cutting edge biostatistical and bioinformatics methodology.

项目概要/摘要 生物统计学和生物信息学 (Bios) 核心（核心 F）为 CFAR 会员提供了获得高度认可的机会。 合格的教职员工团队（核心成员），他们是团队科学领域的专家关键人物。这 组建和部署该团队的目标是响应传统的生物统计和生物信息学 CFAR 会员的服务需求，同时保持在开发和应用方面的创新能力 采用最先进的方法来应对现代社会中出现的统计设计和分析挑战 临床、基础、转化以及社会和行为流行病学研究。 Bios 核心增强了 CFAR 成员通过合作和协商进行的艾滋病毒相关研究的影响和严谨性， 以及通过强调新员工职业发展的培训和指导活动 调查人员。 2016 年实施的创新 Bios Core Liaison 系统，目前已经成熟 资助期，以促进目标 Bios 核心教职人员与所有科学核心和 科学工作组成员。核心提供了一整套服务，为 提案制定、研究设计、数据分析计划、病例报告表和数据库设计，以及 发表科学研究成果。在下一个项目期间，Bios Core 将继续优先考虑新兴技术 艾滋病毒研究人员通过与发展核心的试点资助计划和 临床研究核心支持提案的制定和基于注册的数据的有效使用。同时 届时，我们将培养和加强与已建立的 CFAR 会员的长期合作，以促进 创新且有影响力的团队科学。 Bios 核心的活动将集中于以下具体目标： 目标 1：为 CFAR 成员提供高质量的协作支持，特别强调支持 并加强早期艾滋病毒研究人员的建议； 目标 2：利用核心成员的专业知识支持埃默里 CFAR 的总体使命， 在跨学科研究中发展长期且自我维持的科学合作； 目标 3：通过旨在促进和增强 CFAR 之间和内部的协同作用 传播创新且有影响力的艾滋病毒相关研究方法和实践； 目标 4：促进下一代 Bios 教师担任核心领导职位并吸引有才华的学员 确保核心通过健全和可靠的方法在加强 CFAR 成员的研究方面持续取得长期成功 最先进的生物统计学和生物信息学方法。