Integrated Training in Engineering and Diabetes

工程和糖尿病综合培训

• 批准号: 10457263
• 负责人: Jamey D. Young
• 金额: $ 34.77万
• 依托单位: VANDERBILT UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-08-01 至 2024-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10457263
• 关键词: Diabetes Mellitus; Engineering; Training

PROJECT SUMMARY/ABSTRACT Diabetes is a complex disease with multiple risk factors/causes, and a broad spectrum of complications. The rational development of novel clinical treatments for diabetes will require interdisciplinary approaches to integrate multiple data sources, build predictive models, and develop new technologies that will together reveal the multifactorial underpinnings of the disease. Such approaches are well-developed in engineering, but they have not been widely applied to diabetes, in part because of a lack of people skilled in both engineering and biomedical research. To develop such an interdisciplinary workforce, we propose to continue a novel Integrated Training in Engineering and Diabetes (ITED) program to attract both predoctoral students and postdoctoral fellows with engineering and quantitative physical science backgrounds to work on research problems at the interface of engineering and diabetes. Vanderbilt University is an ideal location for this program because of the close integration and proximity of the Schools of Engineering and Medicine, the outstanding environment for diabetes research, and the long-standing tradition of collegiality and collaboration across the Vanderbilt campus. The overall goal of the program is to provide talented individuals from engineering backgrounds with state-of-the-art training in diabetes research, which will give them a broad perspective of both basic biomedical research and associated clinical challenges. Forty-one faculty preceptors, equally distributed between those with an engineering background and a diabetes research focus, will work together to offer a wide variety of research opportunities in engineering and diabetes research. Our program includes: a) a novel dual mentor plan where each trainee performs interdisciplinary research in two labs, b) an efficient didactic program that provides trainees with the necessary knowledge base in a compact time-frame that promotes timely completion of their degree, and c) interactions with other trainees, faculty, and visiting scientists. Two experienced mentors, one from engineering and one from a diabetes research background, will supervise each trainee. This interdisciplinary approach requires the trainees to spend significant time in each of the mentors’ labs. A broad educational program for predoctoral trainees will leverage existing courses in the Schools of Engineering and Medicine, supplemented by research seminars, a monthly Data Club, and an annual ITED Retreat. Postdoctoral trainees with engineering degrees will be specifically recruited to this program, and will participate in all ITED activities. We do not expect the postdoctoral trainees to have a background in diabetes research, so they will achieve competency through didactic instruction. Support for 4 predoctoral trainees and 2 postdoctoral trainees is requested based on the research resources of the faculty preceptors. A Steering Committee that represents the breadth of participating investigators will select trainees based on their academic and research performance, and their promise as independent investigators. The program will provide RCR training and actively seek to support disabled individuals and those from minority groups.

项目概要/摘要 糖尿病是一种复杂的疾病，具有多种危险因素/原因以及广泛的并发症。 合理开发糖尿病新的临床治疗方法需要跨学科方法的整合 多个数据源，建立预测模型，并开发新技术，共同揭示 这种疾病的多因素基础在工程学上已经很成熟，但它们仍然存在缺陷。 尚未广泛应用于糖尿病，部分原因是缺乏工程和生物医学方面的技术人员 为了培养这样一支跨学科的劳动力队伍，我们建议继续开展新型综合培训。 工程与糖尿病（ITED）项目吸引博士前学生和博士后研究员 工程和定量物理科学背景，致力于解决以下领域的研究问题 范德比尔特大学是该项目的理想地点，因为距离很近。 工程学院和医学院的整合和邻近，为糖尿病提供了良好的环境 研究，以及整个范德比尔特校园长期以来的合作与合作传统。 该计划的总体目标是为具有工程背景的人才提供最先进的技术 糖尿病研究培训，这将为他们提供基础生物医学研究和 四十一位教师导师，平均分配给具有相关临床挑战的人。 工程背景和糖尿病研究重点，将共同提供广泛的研究 我们的计划包括：a) 一项新颖的双导师计划，其中 每个学员在两个实验室进行跨学科研究，b) 一个有效的教学计划，提供 受训者在紧凑的时间范围内具备必要的知识基础，从而促进及时完成他们的课程 c) 与其他学员、教师和访问科学家的互动，其中两位经验丰富的导师。 来自工程学和一位来自糖尿病研究背景的人将监督每位学员。 跨学科方法要求学员在每个导师的实验室中花费大量时间。 博士前培训生的教育计划将利用工程学院和 医学，辅以研究研讨会、每月一次的数据俱乐部和每年一次的 ITED 博士后静修。 具有工程学位的学员将被专门招募到该项目，并将参加所有ITED 我们不期望博士后学员有糖尿病研究背景，所以他们会。 通过教学指导获得能力。支持 4 名博士前实习生和 2 名博士后实习生。 根据代表教师导师的研究资源提出要求。 参与研究人员的广度将根据他们的学术和研究表现来选择受训者， 以及他们作为独立调查员的承诺，该计划将提供 RCR 培训并积极寻求 支持残疾人和少数群体。