CSHL 2015 Wiring the Brain

CSHL 2015 连接大脑

• 批准号: 8836783
• 负责人: DAVID J. STEWART
• 金额: $ 2万
• 依托单位: COLD SPRING HARBOR LABORATORY
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-09-30 至 2015-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8836783
• 关键词: Affect; Archives; Autistic Disorder; Books; Brain; Clinical; Cognitive; Cognitive Science; Collaborations; Communities; Complex; Data; Defect; Development; Discipline; Ensure; Environment; Faculty; Fostering; Functional disorder; Genes; Genetic; Genetic Variation; Goals; Human; International; Invertebrates; Ireland; Laboratories; Lead; Length of Stay; Mediating; Memory; Mental disorders; Methodology; Mind; Modeling; Molecular; Mutation; Neurodevelopmental Disorder; Neuroglia; Neurons; Neurosciences; New York; Oral; Participant; Pattern; Postdoctoral Fellow; Process; Program Development; Psyche structure; Psychology; Psychopathology; Published Comment; Reagent; Research; Research Personnel; Rodent; Sales; Schedule; Schizophrenia; Science; Scientist; Series; Societies; Structure; Synapses; System; Technology; Thinking; Woman; Work; abstracting; base; data exchange; developmental neurobiology; experience; graduate student; heuristics; improved; innovation; interest; laboratory facility; meetings; nervous system disorder; neural circuit; neurodevelopment; neurophysiology; planetary Atmosphere; posters; psychogenetics; public health relevance; symposium; unpublished works

 DESCRIPTION (provided by applicant): Cold Spring Harbor Laboratory Conference on Wiring the Brain March 24-28, 2015 Abstract The Wiring the Brain meeting will take place March 24 -28, 2015 at Cold Spring Harbor Laboratory, New York. The main goal of this meeting is to bring together researchers from diverse fields to explore how brain connectivity is established, how genetic variation can affect these processes, how circuit and network function are affected by defects in neural development and how this can lead to psychiatric and neurological disease. The goal is to stimulate cross-talk between scientists approaching questions of brain connectivity from traditionally separate disciplines. The main themes of the meeting are: How is the connectivity of the brain established? How can we probe, visualize and model brain connectivity? How does the brain's circuitry mediate its functions? How do the functions of brain circuits generate mental experience? What happens when the wiring of the brain is disrupted? A particular focus of the meeting will be on mammalian systems (from rodents to human) and on trying to understand the genetic, neurodevelopmental and neurophysiological bases of psychiatric and neurological disorders. This distinguishes from the "Neural Circuit" meeting at CSHL, which include substantial studies in invertebrates with more focus on cellular and molecular mechanisms. Our hope is to help develop a heuristic framework to explain how mutations in genes affecting neural development alter brain connectivity, affect brain functions and ultimately lead to psychopathology. The meeting will cover a broad spectrum of topics ranging from detailed analysis and perturbation of specific circuits to whole brain connectivity to clinical implications at the organismal level. Session themes include: Genetically programmed development; Activity-dependent development; Genetics of neurodevelopmental disorders; Modeling neurodevelopmental disorders; Connectivity - from synapses to systems; Circuits - function and dysfunction; Wiring the human brain; and Cognitive development - the emergence of the mind. Each session will be chaired by a leading scientist in the field. Oral presentations will be given by a group of distinguished invited speakers as well as speakers selected from submitted abstracts. Selected speakers will include graduate students, postdoctoral fellows and junior faculty aiming for maximal inclusion of young investigators. Of special importance are the two poster sessions, where many participants can present their work in an atmosphere conducive to informal discussion. The meeting will be of moderate size and we expect about 250 people to attend, the vast majority of whom will be presenting a poster or talk.

 描述（适用提供）：2015年3月24日至28日，摘要大脑会议的冷泉港实验室会议摘要大脑会议将于2015年3月24日至28日在纽约冷春港实验室举行。这次会议的主要目标是将来自潜水员领域的研究人员汇集在一起​​，以探索大脑连通性的建立，遗传变异如何影响这些过程，电路和网络功能如何受神经发育缺陷的影响以及这如何导致精神病和神经系统疾病。目的是刺激科学家之间的跨谈话，该科学家与传统分开的学科接近大脑连通性问题。会议的主要主题是：大脑的连通性如何建立？我们如何探测，可视化和建模大脑连接性？大脑电路如何介导其功能？大脑电路的功能如何产生心理体验？当禁用大脑接线时会发生什么？会议的一个特殊重点将是哺乳动物系统（从啮齿动物到人），并试图了解精神病和神经系统疾病的遗传，神经发育和神经生理基础。这与CSHL上的“神经回路”会议区分开来，其中包括对无脊椎动物的实质研究，更关注细胞和分子机制。我们的希望是帮助开发一个启发式框架，以解释影响神经发育的基因突变如何改变大脑连通性，影响大脑功能并最终导致心理病理学。这次会议将涵盖广泛的主题，从详细分析和特定电路的扰动到整个大脑连接性到有机水平的临床意义。会话主题包括：基因编程的开发；活动依赖性发展；神经发育障碍的遗传学；建模神经发育障碍；连接 - 从突触到系统；电路 - 功能和功能障碍；接线人脑；和认知发展 - 思想的出现。每个会议将由该领域的主要科学家主持。口头演示将由一组杰出的邀请发言人以及从提交摘要中选择的演讲者进行。选定的演讲者将包括研究生，博士后研究员和初级教职员工，以最大程度地纳入年轻调查员。这两个海报会议特别重要，许多参与者可以在氛围中介绍他们的作品以进行非正式讨论。这次会议的规模将是中等的，我们希望大约250人参加，其中绝大多数将介绍海报或谈话。