Advanced Spatiomotor Rehabilitation for Navigation in Blindness & Visual Impairment

先进的失明导航空间运动康复

• 批准号: 10441467
• 负责人: Lora T. Likova
• 金额: $ 48.21万
• 依托单位: SMITH-KETTLEWELL EYE RESEARCH INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-04-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10441467
• 关键词: Auditory; Behavioral; Blindness; Brain; Brain imaging; Cognition; Cognitive; Data; Databases; Decision Making; Development; Diffusion Magnetic Resonance Imaging; Employment; Environment; Etiology; Face; Functional Magnetic Resonance Imaging; Goals; Grant; Hand; Image; Independent Living; Individual; Investigation; Knowledge; Learning; Life; Literature; Location; Locomotion; Maintenance; Manuals; Maps; Measures; Memory; Methods; Modality; Multimodal Imaging; Neuronal Plasticity; Neurosciences; Performance; Plant Roots; Population; Problem Solving; Production; Protocols documentation; Psyche structure; Psychological Transfer; Rehabilitation therapy; Research; Route; Running; Self-Help Devices; Short-Term Memory; Stimulus; Tactile; Technology Assessment; Testing; Time; Training; Translating; Travel; Vision; Visual impairment; Visually Impaired Persons; aging brain; base; blind; cognitive enhancement; cognitive function; cognitive skill; design; flexibility; haptics; imaging platform; improved; innovation; innovative technologies; interdisciplinary approach; mental representation; multidisciplinary; multimodality; neuroimaging; novel; novel strategies; operation; programs; relating to nervous system; sight restoration; skills; spatial memory; theories; tool; virtual reality system; visual motor; way finding; web-accessible

Advanced Spatiomotor Rehabilitation for Navigation in Blindness & Visual Impairment ABSTRACT We propose a radical new multidisciplinary approach to navigation training in blindness and visual impairment. Successful navigation requires the development of an accurate and flexible mental, or cognitive, map of the navigational space and of the route trajectory required to travel from the current to the target location. The Cognitive-Kinesthetic (C-K) Rehabilitation Training that we have developed in the preceding period utilizes a unique form of blind memory-guided drawing to develop cognitive mapping to a high level of proficiency. Particular reliance must be placed on such mental maps (supported only by tactile and auditory inputs), and on the ability to use them effectively for spatiomotor control, when vision with its built-in spatial functionality is lost. There is, however, a fundamental gap in the practice of Orientation and Mobility (O&M), which is the lack of a specific emphasis on enhancement of these cognitive roots of spatiomotor activity, despite their known importance for navigation in the visually impaired. We therefore propose a rigorous multidisciplinary approach to this issue, which lies at the intersection of the fields of spatiomotor rehabilitation, blindness assessment technologies, and brain function, each a focus of one Specific Aim. To train the spatial cognition abilities underlying successful navigation, the current proposal aims to translate the power of the C-K Rehabilitation Training, which we developed in the preceding grant period for the manual domain of operation, to the domain of navigation. The blind and visually impaired trainees will quickly learn how to generate precise and stable cognitive maps of haptically explored raised-line images or tactile maps, and how to use the formed cognitive maps to confidently guide both drawing ’hand navigation’ on a map-scale, and whole-body blind navigation on the macro-scale. Once translated to navigation, our preliminary data show that this efficient and enjoyable training will rapidly and sustainably enhance spatial cognition functions both for improved navigation performance and for enhancement of more general spatial cognitive skills. Beyond its practical advantages, the training will also serve as an efficient tool to drive and study training-based neuroplasticity mechanisms through a comprehensive whole-brain multimodal brain imaging platform. These neuroplastic are difficult to study properly without a rapid and effective training protocol, which has not previously been available. Taken together, the research program will overcome the relative disconnect between expanding neuroscience knowledge and approaches to practical blindness rehabilitation. The knowledge gained will in turn inform and benefit further rehabilitative developments, both in navigation proficiency and in more general cognitive function in the blind population. !

先进的空间运动康复治疗失明和视力障碍患者的导航 抽象的 我们提出了一种全新的多学科方法来进行失明和视觉导航训练 成功的导航需要发展准确而灵活的心理或认知能力。 导航空间地图以及从当前位置到目标位置所需的路线轨迹图 我们在前面开发的认知动觉（C-K）康复训练。 时期利用一种独特的盲目记忆引导绘画形式将认知图发展到高水平 必须特别依赖这种心理地图（仅由触觉和触觉支持）。 听觉输入），以及当视觉具有其能力时有效地使用它们进行空间运动控制的能力 然而，在方向和方向的实践中存在根本性的差距。 移动性（O&M），缺乏对增强这些认知根源的具体强调 空间运动活动，尽管众所周知它们对于视障者的导航很重要。 因此，我们建议对这个问题采取严格的多学科方法，该方法处于交叉点 空间运动康复、失明评估技术和大脑功能领域，每个领域都是焦点 一个具体目标是训练成功导航的空间认知能力，当前的目标是训练成功导航的空间认知能力。 该提案旨在转化我们在之前开发的 C-K 康复训练的力量 授予手动操作领域、盲人和视觉导航领域的时间。 受损的学员将很快学会如何生成精确且稳定的触觉探索认知图 凸起的线条图像或触觉地图，以及如何使用形成的认知地图来自信地引导两者 在地图尺度上绘制“手动导航”，在宏观尺度上绘制全身盲导航。 转化为导航，我们的初步数据表明，这种高效、愉快的培训将快速且有效地进行。 可持续地增强空间认知功能，以提高导航性能和 增强更一般的空间认知技能。 除了其实际优势外，培训还将成为驾驶和学习的有效工具 通过全面的全脑多模态脑成像进行基于训练的神经可塑性机制 如果没有快速有效的培训方案，这些神经塑料很难正确研究， 综合起来，该研究计划将克服相对的困难。 扩大神经科学知识与实际失明康复方法之间的脱节。 所获得的知识反过来将为导航领域的进一步康复发展提供信息并有益于其发展 盲人群体的熟练程度和更一般的认知功能。 ！