Research Examining Factors Associated with the Opioid Crisis among Underserved African Americans (REFOCUS)

研究审查与服务不足的非裔美国人中阿片类药物危机相关的因素（REFOCUS）

基本信息

批准号：
10434906
负责人：
Danelle J Stevens-Watkins
金额：
$ 63.51万
依托单位：
UNIVERSITY OF KENTUCKY
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-09-30 至 2025-07-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10434906
关键词：
Address Adult African American African American population Age Area Attention Buprenorphine Cessation of life Characteristics Child Rearing Communities Complex Comprehension Criminal Justice Data Data Sources Dimensions Discrimination Dose Drug usage Employment Epidemic Ethnic Origin Evolution Female Future Gender Generations Goals Healthcare Systems Heroin Intervention Interview Kentucky Libraries Link Longevity Mediating Mental Health Methadone Methods Morbidity - disease rate National Institute of Drug Abuse Outcome Overdose Pain Participant Patients Pattern Pharmacotherapy Policies Population Public Health Race Reporting Research Research Personnel Research Project Grants Risk Sampling Stress Structure Surveys Techniques Testing Treatment outcome Underrepresented Populations Underserved Population base cohort design distrust drug testing evidence base experience health care availability health communication illicit drug use improved insight low socioeconomic status male marginalized population men misuse of prescription only drugs mortality risk older women opioid epidemic opioid overdose opioid use opioid user physical conditioning pill prescription opioid prescription opioid misuse recruit response social synthetic opioid theories treatment services trend young woman

项目摘要

ABSTRACT Opioid-related overdose rates among African Americans have increased exponentially. Given African American opioid users have the lowest treatment completion rates when compared to other races/ethnicities there is increased risk for mortality and morbidity. As a result, there is a dire need to better understand this fatal epidemic among this historically underserved group. Using the theory of Subcultural Evolution and Drug Use which suggests cultural and generational influences are linked to drug use patterns and risks among African Americans, the Research Examining Factors Associated with the Opioid Crisis among Underserved African Americans (REFOCUS) project will employ a within-racial group, mixed-methods design among African American adults in the community. The overall objective is to better understand the complex structural, social, and cultural factors that differentially influence NMPOU, other nonmedical prescription drug use and treatment service use among African Americans. Ultimately, our goal is to gather data that will inform culturally-tailored interventions to reduce NMPOU and better facilitate initiation and completion of treatment. The REFOCUS project has three aims: 1) To understand cultural and generational characteristics associated with NMPOU, other NMPDU, illicit drug use and treatment service use. We will conduct in-depth interviews with approximately 40 African American nonmedical prescription opioid users stratified by gender and age to understand NMPOU across the lifespan within the context of lived experience. Using thematic analysis, data will be gathered to culturally-tailor the survey. 2) To assess structural, social and cultural patterns of NMPOU, other NMPDU, illicit drug use and treatment service use among 800 (400 = male and 400 = female) African American NMPO users. We will conduct cross-sectional face-to-face culturally-informed surveys (modified by information obtained in Aim 1) and drug testing using targeted recruitment and stratified sampling by age and gender. 3) To pretest messaging generated from initial findings that will inform targeted interventions specific to African American nonmedical prescription opioid users. We will conduct in-depth, semi-structured interviews and using health communication techniques, we will develop a library of cultural, gender, and generational specific messages related to decreasing NMPOU and increasing treatment engagement and retention. We will test these messages that will be constructed from Aim 1 and Aim 2 data with approximately 40 African American nonmedical prescription opioid users stratified by gender and age. This pretesting task will prepare us to conduct a fully powered RCT as the next step in our research. This underrepresented new investigator led project directly aligns with the PAR and NIDA’s priority focus area of “addressing real-world complexities”. As this high-impact project focuses on a marginalized group underrepresented in opioid use research and it has the potential to yield insights on ways to culturally-tailor future interventions for African Americans.

抽象的鉴于非洲人，非裔美国人中与阿片类药物相关的过量用药率呈指数增长。与其他种族/民族相比，美国阿片类药物使用者的治疗完成率最低因此，迫切需要更好地了解这一点。利用亚文化进化和毒品理论，在这个历史上服务不足的群体中发生了致命的流行病。使用表明文化和代际影响与吸毒模式和风险有关非裔美国人，研究检查与服务不足的阿片类药物危机相关的因素非裔美国人 (REFOCUS) 项目将在非裔美国人中采用种族内混合方法设计社区中的美国成年人的总体目标是更好地理解复杂的结构、社会、对 NMPOU、其他非医疗处方药的使用和治疗产生不同影响的文化因素最终，我们的目标是收集数据，为文化定制提供信息。减少 NMPOU 并更好地促进治疗的开始和完成的干预措施。项目有三个目标：1）了解与相关的文化和代际特征 NMPOU、其他 NMPDU、非法药物使用和治疗服务使用情况我们将进行深入访谈。约 40 名非洲裔美国人非医疗处方阿片类药物使用者按性别和年龄分层， NMPOU 在生活经验的背景下跨生命周期使用主题分析和数据。将收集起来进行文化定制调查 2) 评估结构、社会和文化模式。 NMPOU、其他 NMPDU、800 人中的非法药物使用和治疗服务使用（400 名 = 男性，400 名 = 女性）非裔美国 NMPO 用户将进行跨部门面对面的文化了解。调查（根据目标 1 中获得的信息进行修改）和使用有针对性的招募和分层进行药物测试 3) 按年龄和性别进行抽样，预先测试根据初步调查结果生成的信息。我们将针对非洲裔美国非医疗处方阿片类药物使用者采取有针对性的干预措施。进行深入的半结构化访谈并使用健康沟通技术，我们将制定与减少 NMPOU 和增加相关的文化、性别和代际特定信息的图书馆我们将测试根据目标 1 和目标构建的这些消息。 2 份数据，涉及大约 40 名非医疗处方阿片类药物使用者，按性别和年龄分层这项预测试任务将为我们下一步研究进行全面的随机对照试验做好准备。这个代表性不足的新研究者主导的项目与 PAR 和 NIDA 的优先重点直接一致 “解决现实世界的复杂性”领域，因为这个具有高影响力的项目重点关注边缘化群体。在阿片类药物使用研究中代表性不足，它有可能产生关于文化定制方法的见解未来对非裔美国人的干预措施。