P20 Exploratory Center for Precision Health in Diverse Populations

P20多元化人群精准健康探索中心

• 批准号: 10415902
• 负责人: Abraham Aizer Brody
• 金额: $ 1.72万
• 依托单位: NEW YORK UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-08-08 至 2024-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10415902
• 关键词: Accountability; Adult; Affect; Age; Area; Behavioral; Biological; Biological Markers; Biology; Communities; Complex; Data Element; Development; Discipline of Nursing; Drug usage; Educational workshop; Ensure; Environmental Risk Factor; Ethnic Origin; Evaluation; Fellowship; Fostering; Functional disorder; Funding; Geriatric Nursing; Grant Review; HIV; Healthcare; Individual; Institutes; Journals; Learning; Measurement; Mentorship; Metabolic syndrome; Methodology; Methods; NCI Scholars Program; National Institute of Drug Abuse; Needs Assessment; Nurses; Nursing Research; Outcome; Patients; Population Heterogeneity; Postdoctoral Fellow; Precision Health; Process; Race; Research; Research Personnel; Resources; Science; Scientist; Series; Stream; Structure; Symptoms; Technology; Textiles; United States National Institutes of Health; Visit; Writing; base; career; clinical practice; college; design; ethical legal social implication; evidence base; experience; faculty support; member; multimodality; multiple chronic conditions; peer; peer coaching; programs; ranpirnase; research and development; research study; sex; skills; visiting scholar

PROJECT SUMMARY The Enrichment Program of the P20 Exploratory Center for Precision Health in Diverse Populations focuses on developing nurse scientists in Metabolic Syndrome (MetS) and its resulting multiple chronic conditions (MCC). The Enrichment Program seeks to foster the development early career nurse scientists into successful, NIH-funded, independent investigators. The overarching aims of the Enrichment Program are to support nurse scientists in learning how to (1) Understand and evaluate how the underlying biology and pathophysiology of MetS and its resulting MCC leads to differential symptom and biomarker expression. (2) Analyze the impact of race, ethnicity, age, and sex on biological, behavioral, and environmental factors leading to MetS and its resulting MCC, and how these factors influence the methods needed to effectively perform nursing research in diverse populations. (3) Take MetS and its resulting MCC bench research (T1/T2) to the bedside (T3) and integrate it into everyday clinical practice (T4). (4) Develop effective and efficient collaborative interdisciplinary teams to carry out research in MetS and its resulting MCC. (5) Understand and effectively use core data elements in the design and implementation of research studies in MetS and its resulting MCC. (6) Evaluate the ethical, legal and social implications of performing science on MetS and its resulting MCC in diverse populations, including the use of biomarkers. The center will achieve these aims by leveraging the extensive resources available at the NYU Rory Meyers College of Nursing (NYU Meyers) and the greater NYU scientific community as well as by developing new programs. Existing resources at NYU Meyers include internal grant reviews, speaker series, the NIDA-funded P30 Center in Drug Use and HIV Research, the Hartford Institute for Geriatric Nursing, and the NSF-funded X-lab, which brings technology solutions to healthcare. New programs developed specifically to provide individual, group, and peer mentoring. Programs in these areas will include a Science in Progress monthly seminar, a journal club, and a writing accountability and peer mentoring group. We will also expand mentorship and capacity in our post-doctoral fellowships and visiting scholar programs in the area of MetS and its resulting MCC. The Enrichment Program will develop and implement targeted seminars and day-long methodologic and scientific programs, targeted to areas of need as identified through an annual needs assessment. The Enrichment Program activities will be highly sustainable, as they will be woven into the fabric of NYU Meyers and fit into existing resources, structures, and funding streams. By the end of the five year P20 period, the new programs will be self-sustained by the faculty and by support from the Dean of NYU Meyers. The Enrichment Program will be evaluated by an experienced external scientist, who will perform an annual review based on process and outcome measurements. The evaluation will be reviewed by the Enrichment Program Director and the Administrative Core to ensure that the program maximizes the development of early-career nurse scientists in research on MetS and its resulting MCC in diverse populations.

项目概要 P20多元化人群精准健康探索中心拓展计划重点关注 关于培养代谢综合征（MetS）及其导致的多种慢性病的护士科学家 （中冶集团）。丰富计划旨在促进早期职业护士科学家的发展，使其成为成功的、 NIH 资助的独立研究人员。丰富计划的总体目标是支持护士 科学家们学习如何（1）理解和评估潜在的生物学和病理生理学 MetS 及其产生的 MCC 会导致不同的症状和生物标志物表达。 (2) 影响分析 种族、民族、年龄和性别对导致 MetS 及其影响的生物、行为和环境因素的影响 由此产生的 MCC，以及这些因素如何影响有效开展护理研究所需的方法 不同的人群。 (3) 将 MetS 及其产生的 MCC 基准研究 (T1/T2) 带到临床 (T3) 并 将其融入日常临床实践（T4）。 (4) 发展有效、高效的跨学科协作 团队对 MetS 及其产生的 MCC 进行研究。 (5)了解并有效利用核心数据 MetS 及其由此产生的 MCC 的研究设计和实施的要素。 (6) 评估 对 MetS 进行科学研究的伦理、法律和社会影响及其在不同领域产生的 MCC 人群，包括生物标志物的使用。该中心将通过利用广泛的资源来实现这些目标 纽约大学罗里·迈耶斯护理学院 (NYU Meyers) 和更大的纽约大学科学学院提供的资源 社区以及开发新项目。纽约大学迈耶斯分校的现有资源包括内部拨款 评论、演讲系列、NIDA 资助的 P30 药物使用和艾滋病毒研究中心、哈特福德研究所 老年护理，以及 NSF 资助的 X 实验室，该实验室为医疗保健提供技术解决方案。新节目 专门为提供个人、团体和同伴指导而开发。这些领域的计划将包括 《科学进展》每月研讨会、期刊俱乐部以及写作责任和同行指导小组。 我们还将扩大博士后奖学金和访问学者项目的指导和能力 MetS 区域及其产生的 MCC。丰富计划将制定并实施有针对性的 研讨会和为期一天的方法和科学计划，针对通过确定的需要领域 年度需求评估。丰富计划活动将具有高度可持续性，因为它们将 融入纽约大学迈耶斯大学的结构，并融入现有的资源、结构和资金流。由 五年 P20 期结束后，新项目将由教员和学校的支持自行维持 纽约大学迈耶斯分校院长。丰富计划将由一位经验丰富的外部科学家进行评估，他将 根据过程和结果测量进行年度审查。评估结果将由 丰富项目主任和行政核心，以确保该项目最大化 早期职业护士科学家在 MetS 及其在不同人群中产生的 MCC 研究中的发展。