Cancer Imaging

癌症影像

• 批准号: 10411094
• 负责人: Jason Thanh Lee
• 金额: $ 9.19万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-06-04 至 2027-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10411094
• 关键词: Accounting; Animal Disease Models; Biological Process; Bioluminescence; Budgets; Cancer Biology; Cancer Center Support Grant; Consult; Cyclotrons; Data Analyses; Detection; Diagnostic; Discipline of Nuclear Medicine; Disease Progression; Doctor of Philosophy; Educational workshop; Ensure; Faculty; Fluorescence; Fostering; Funding; Goals; Hematologic Neoplasms; Image; Imaging Device; Imaging technology; Immunology; Individual; Institutes; Knowledge; Laboratories; Magnetic Resonance Imaging; Magnetism; Malignant Neoplasms; Medical; Medical Imaging; Molecular Biology; Monitor; Oncology; Physics; Play; Positron-Emission Tomography; Publications; Radiobiology; Radiochemistry; Research; Research Personnel; Resource Sharing; Role; Scientist; Screening for cancer; Services; Site; Technology; Therapeutic; Time; Tracer; Training; Translational Research; Work; Workplace; X-Ray Computed Tomography; animal facility; animal imaging; anticancer research; assay development; cancer imaging; cancer immunotherapy; cancer stem cell; design; drug development; experience; experimental study; imaging modality; imaging scientist; improved; in vivo; in vivo imaging; instrument; member; molecular imaging; novel diagnostics; novel therapeutic intervention; optical imaging; particle; pre-clinical research; preclinical imaging; programs; theranostics; ultrasound

PROJECT SUMMARY The Cancer Imaging Shared Resource (CI-SR) provides advanced preclinical imaging technologies and services for studying cancer biology, early cancer detection, monitoring disease progression, and developing novel diagnostic and theranostic agents. All major small animal imaging modalities are available, including positron emission tomography (PET), magnetic resonance imaging (MRI), x-ray computed tomography (CT), ultrasound and photoacoustics, magnetic particle imaging (MPI), and optical imaging (e.g., bioluminescence, fluorescence, Cerenkov). Since the last review, the CI-SR has acquired new and upgraded imaging instruments, including the first-of-its-kind MPI scanner. In 2020, 54% of users were SCI investigators accounting for approximately 55% of total usage. Members of the Cancer Imaging, Cancer Biology and Cancer Stem Cells, Cancer Therapeutics, Radiation Biology, Cancer Immunotherapy, and Hematologic Malignancies programs regularly use the CI-SR, with the heaviest use coming from the Cancer Imaging, Cancer Biology and Cancer Stem Cells, and Cancer Therapeutics programs. The CI-SR contributed to over 55 cancer-focused publications (15 high-impact). The annual budget of the CI-SR is $1,021,174, yet the CCSG request is $106,372. Accordingly, the CI-SR leverages extensive institutional support and seeks 10% from CCSG funds. The CI-SR is focused on two major scientific aims: (1) to provide access to state-of-the-art and first-of-its-kind in vivo imaging technologies and services pertinent to cancer research and (2) to educate, train, and consult with SCI members in basic and advanced imaging methods and data analysis through training courses, seminars, and workshops.

项目概要 癌症成像共享资源 (CI-SR) 提供先进的临床前成像技术和服务 用于研究癌症生物学、早期癌症检测、监测疾病进展和开发新药物 诊断和治疗诊断剂。所有主要的小动物成像模式均可用，包括正电子 发射断层扫描 (PET)、磁共振成像 (MRI)、X 射线计算机断层扫描 (CT)、超声波 和光声学、磁粒子成像 (MPI) 和光学成像（例如生物发光、荧光、 切伦科夫）。自上次审查以来，CI-SR 已采购了新的和升级的成像仪器，包括 首创的 MPI 扫描仪。 2020 年，54% 的用户是 SCI 研究者，约占 55% 总使用量。癌症影像学、癌症生物学和癌症干细胞、癌症治疗学的成员， 放射生物学、癌症免疫治疗和血液恶性肿瘤项目定期使用 CI-SR、 使用最多的是癌症成像、癌症生物学和癌症干细胞以及癌症 治疗计划。 CI-SR 发表了超过 55 篇以癌症为重点的出版物（其中 15 篇具有高影响力）。这 CI-SR 的年度预算为 1,021,174 美元，而 CCSG 的请求为 106,372 美元。因此，CI-SR 利用 广泛的机构支持，并寻求 CCSG 资金的 10%。 CI-SR 重点关注两个主要科学领域 目标：(1) 提供最先进、首创的体内成像技术和服务 与癌症研究相关；(2) 向 SCI 成员提供基础和高级方面的教育、培训和咨询 通过培训课程、研讨会和讲习班进行成像方法和数据分析。