VIDEOTAPE FOR RECRUITMENT TO ONCOLOGY CLINICAL TRIALS

肿瘤学临床试验招募视频

• 批准号: 2104244
• 负责人: NANCY E AVIS
• 金额: $ 8.03万
• 依托单位: NEW ENGLAND RESEARCH INSTITUTES, INC.
• 依托单位国家: 美国
• 财政年份: 1994
• 资助国家: 美国
• 起止时间: 1994-09-30 至 1995-08-14
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/2104244
• 关键词: education evaluation /planning; health science research; human subject; neoplasm /cancer education; videotape /videodisc; volunteer

Patient accrual to clinical trials is a difficult problem. It has been estimated that total accrual to NCI-supported cancer treatment trials in adults represents a fraction (<10%) of the number of patients potentially available. It has been further estimated that Cooperative Group adjuvant trials accrue 1% to 1.5% of potentially available patients. Three major NCI supported studies had average rates that were 32%, 113%, and 119% slower than planned projection rates. The purpose of this SBlR is to develop and evaluate a videotape for recruiting patients to cancer clinical trials. The Specific Aims of the videotape are: (1) To increase recruitment of patients to cancer clinical trials; (2) To increase patient's understanding of and satisfaction with their participation in clinical trials; and (3) To provide a cost-effective, standardized recruitment strategy for clinical trials. These aims will be accomplished through the development of a videotape. This videotape will serve as an educational tool to describe clinical trials and to address patient's fears and concerns regarding participation. During Phase I of the proposed SBlR we will determine the content needs of the videotape and the most effective presentation method. During Phase II, the videotape will be produced and evaluated. The end product of this SBIR will be a videotape that can be used for recruitment to clinical trials. While the proposed videotape will be developed and tested in the context of breast cancer clinical trials, the method developed will be transferable to other clinical trials.

临床试验的患者应计是一个难题。它一直 估计 NCI 支持的癌症治疗试验的总应计 成人仅占潜在患者数量的一小部分（<10%） 可用的。进一步估计合作组佐剂 试验吸引了 1% 至 1.5% 的潜在患者。三大 NCI 支持的研究的平均成功率分别为 32%、113% 和 119% 比计划的预测速度慢。该 SBlR 的目的是 开发并评估招募癌症患者的录像带 临床试验。录像带的具体目的是： (1) 增加 招募患者参加癌症临床试验； (2) 增加 患者对其参与的理解和满意度 临床试验； (3) 提供具有成本效益的、标准化的 临床试验的招募策略。这些目标将会实现 通过录像带的开发。该录像带将作为 描述临床试验并解决患者问题的教育工具 对参与的恐惧和担忧。在拟议的第一阶段 SBlR 我们将确定录像带的内容需求和最 有效的呈现方法。在第二阶段，录像带将被 制作并评价。该 SBIR 的最终产品将是一盘录像带 可用于招募临床试验。虽然提议的 录像带将在乳腺癌背景下开发和测试 临床试验，开发的方法将可转移到其他 临床试验。